{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T06:55:57Z","timestamp":1767164157303,"version":"build-2238731810"},"reference-count":0,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[1973,10,1]],"date-time":"1973-10-01T00:00:00Z","timestamp":118281600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Appl Microbiol"],"published-print":{"date-parts":[[1973,10]]},"abstract":"<jats:p>\n                    Extracts of\n                    <jats:italic>Fusarium poae<\/jats:italic>\n                    (NRRL 3287) grown either on sterile corn at 8 C or in Richards solution at room temperature were shown to have emetic activity in pigeons at nonlethal concentration under conditions of oral and intravenous administration. The causative agent was found to be T-2 toxin (3-hydroxy-4,15-diacetoxy-8-[3-methylbutyryloxy]-12,13-epoxy-\u0394\n                    <jats:sup>9<\/jats:sup>\n                    -trichothecene). Oral and intravenous mean toxic dose values for this compound were found to be 0.72 and 0.15 mg\/kg, respectively, as compared with an oral mean lethal dose of 2.75 mg\/kg. The fact that T-2 toxin causes emesis at nonlethal concentrations may explain, at least in part, the observance of vomiting as a symptom resulting from ingestion of cereal grains infected with toxic\n                    <jats:italic>Fusarium<\/jats:italic>\n                    species containing T-2 or a similar toxin.\n                  <\/jats:p>","DOI":"10.1128\/am.26.4.540-543.1973","type":"journal-article","created":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T03:30:50Z","timestamp":1607139050000},"page":"540-543","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":21,"title":["T-2 Toxin as an Emetic Factor in Moldy Corn"],"prefix":"10.1128","volume":"26","author":[{"given":"Robert A.","family":"Ellison","sequence":"first","affiliation":[{"name":"School of Pharmacy, University of Wisconsin, Madison, Wisconsin 53711"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank N.","family":"Kotsonis","sequence":"additional","affiliation":[{"name":"School of Pharmacy, University of Wisconsin, Madison, Wisconsin 53711"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","container-title":["Applied Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/am.26.4.540-543.1973","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/am.26.4.540-543.1973","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T09:10:09Z","timestamp":1645607409000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/am.26.4.540-543.1973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1973,10]]},"references-count":0,"aliases":["10.1128\/aem.26.4.540-543.1973"],"journal-issue":{"issue":"4","published-print":{"date-parts":[[1973,10]]}},"alternative-id":["10.1128\/am.26.4.540-543.1973"],"URL":"https:\/\/doi.org\/10.1128\/am.26.4.540-543.1973","relation":{},"ISSN":["0003-6919"],"issn-type":[{"value":"0003-6919","type":"print"}],"subject":[],"published":{"date-parts":[[1973,10]]},"assertion":[{"value":"1973-10-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}