{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T00:13:17Z","timestamp":1789776797840,"version":"4.0.1"},"reference-count":25,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:00:00Z","timestamp":1762214400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:00:00Z","timestamp":1762214400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["ASM Case Rep"],"published-print":{"date-parts":[[2025,11,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:sec>\n                      <jats:title>Background<\/jats:title>\n                      <jats:p>\n                        <jats:italic toggle=\"yes\">Stenotrophomonas maltophilia<\/jats:italic>\n                        is a rising opportunistic organism among hospitalized patients, leading to outbreak infections. It is known to be a nosocomial pathogen resistant to multiple antibiotics and may be transmitted via contaminated hospital equipment. Its infection can lead to cardiac complications, although very rare.\n                      <\/jats:p>\n                    <\/jats:sec>\n                    <jats:sec>\n                      <jats:title>Case Summary<\/jats:title>\n                      <jats:p>\n                        We present a case of a 63-year-old patient who presented with insidious symptoms of fever, chills, and chest discomfort and was admitted for the management of prosthetic valve infective endocarditis caused by\n                        <jats:italic toggle=\"yes\">S. maltophilia<\/jats:italic>\n                        evident by positive blood cultures and visualized vegetations on the mitral valve by echocardiography. The hospital stay was complicated by two embolic strokes. The patient underwent successful surgical replacement of the prosthetic mitral valve. However, given the patient\u2019s significant disability and morbidity, he required assistance in performing the activities of daily living in addition to placement of a gastrostomy tube due to the high risk of aspiration.\n                      <\/jats:p>\n                    <\/jats:sec>\n                    <jats:sec>\n                      <jats:title>Conclusion<\/jats:title>\n                      <jats:p>\n                        <jats:italic toggle=\"yes\">S. maltophilia<\/jats:italic>\n                        infective endocarditis is a rare but serious infection that warrants immediate attention with prompt initiation of intravenous antibiotics. In addition, and when indicated, surgical intervention can lead to successful management and minimize the risk of complications, morbidity, and mortality.\n                      <\/jats:p>\n                    <\/jats:sec>\n                  <\/jats:sec>","DOI":"10.1128\/asmcr.00005-25","type":"journal-article","created":{"date-parts":[[2025,7,9]],"date-time":"2025-07-09T13:00:51Z","timestamp":1752066051000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":3,"title":["<i>Stenotrophomonas maltophilia<\/i>\n                    infective endocarditis complicated by two embolic strokes: a rare case report and treatment approach"],"prefix":"10.1128","volume":"1","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5844-7153","authenticated-orcid":true,"given":"Khaled","family":"Qadabashi","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00wmm6v75","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Internal Medicine, American University of Beirut Medical Center","place":["Beirut, Lebanon"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6552-9293","authenticated-orcid":false,"given":"Hadi","family":"Itani","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Northwell Health, Staten Island University Hospital","place":["New York, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moied","family":"Al Sakan","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00wmm6v75","id-type":"ROR","asserted-by":"publisher"}],"name":"Division of Cardiology, Department of Internal Medicine, American University of Beirut Medical Center","place":["Beirut, Lebanon"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike","family":"Ghabally","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03mzvxz96","id-type":"ROR","asserted-by":"publisher"}],"name":"Division of Cardiology, Department of Internal Medicine, Aleppo University Hospital","place":["Aleppo, Syria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George F.","family":"Araj","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00wmm6v75","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Pathology and Laboratory Medicine, American University of Beirut Medical Center","place":["Beirut, Lebanon"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.11.1.57"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(09)70083-0"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/14787210.2020.1730178"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1067\/mhl.2000.108362"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/0036554021000026977"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-37920"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-008-0994-5"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-2-174"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s100960050081"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.49.3701"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihj.2016.07.005"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.medmal.2018.09.004"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1080\/00015458.2008.11680216"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2004.09.002"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/000331970205300107"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics10101226"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciae403"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2014.55.4.987"},{"key":"e_1_3_3_20_2","volume-title":"EUCAST guidance document on Stenotrophomonas maltophilia. Version 2, November 2024","author":"EUCAST","year":"2024","unstructured":"EUCAST. 2024. EUCAST guidance document on Stenotrophomonas maltophilia. Version 2, November 2024. European Committee on Antimicrobial Susceptibility Testing."},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.2174\/1872208316666220512121205"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11121788"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00559-20"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.38613"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00618-22"},{"key":"e_1_3_3_26_2","volume-title":"CLSI supplement M100Performance standards for antimicrobial susceptibility testing","author":"Clinical and Laboratory Standards Institute (CLSI)","year":"2024","unstructured":"Clinical and Laboratory Standards Institute (CLSI). 2024. CLSI supplement M100. 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