{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T16:42:24Z","timestamp":1792082544406,"version":"4.4.0"},"reference-count":30,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T00:00:00Z","timestamp":1741046400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T00:00:00Z","timestamp":1741046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["ASM Case Rep"],"published-print":{"date-parts":[[2025,3,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:sec>\n            <jats:title\/>\n            <jats:sec>\n              <jats:title>\n                <jats:bold>Background<\/jats:bold>\n              <\/jats:title>\n              <jats:p>Japanese encephalitis virus (JEV) is a mosquito-borne pathogen responsible for Japanese encephalitis (JE) clinical cases in Asia and the Western Pacific. Non-JE-vaccinated patients can develop potentially life-threatening neurologic forms.<\/jats:p>\n            <\/jats:sec>\n            <jats:sec>\n              <jats:title>\n                <jats:bold>Case Summary<\/jats:bold>\n              <\/jats:title>\n              <jats:p>Here, we present two severe, non-fatal JEV cases in returning travelers from Cambodia (Case 1) and Cambodia and Vietnam (Case 2), imported to France in 2023\u20132024. Neither patient was vaccinated, and both presented neurologic symptoms requiring hospitalization. Cases were confirmed by RT-qPCR, IgM, and IgG rise and seroneutralization. Interestingly, this is the second report to describe the detection of the JEV genome in urine by RT-qPCR.<\/jats:p>\n            <\/jats:sec>\n            <jats:sec>\n              <jats:title>\n                <jats:bold>Conclusion<\/jats:bold>\n              <\/jats:title>\n              <jats:p>This study highlights the critical importance of JE vaccination and the implementation of other personal protective measures to avoid mosquito bites when traveling to a JEV-endemic region.<\/jats:p>\n            <\/jats:sec>\n          <\/jats:sec>","DOI":"10.1128\/asmcr.00054-24","type":"journal-article","created":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T08:59:56Z","timestamp":1736240396000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":2,"title":["Report of two severe cases of Japanese encephalitis virus in travelers returning to France, 2023-2024: clinical, diagnostic, and public health implications"],"prefix":"10.1128","volume":"1","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4979-6794","authenticated-orcid":true,"given":"Nazli","family":"Ayhan","sequence":"first","affiliation":[{"name":"National Reference Center for Arboviruses, Inserm-IRBA","place":["Marseille, France"]},{"name":"Unit\u00e9 des Virus \u00c9mergents (UVE: Aix-Marseille Univ, Universit\u00e0 di Corsica, IRD 190, Inserm 1207, IRBA)","place":["Marseille, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7921-9221","authenticated-orcid":false,"given":"Laura","family":"Pezzi","sequence":"additional","affiliation":[{"name":"National Reference Center for Arboviruses, Inserm-IRBA","place":["Marseille, France"]},{"name":"Unit\u00e9 des Virus \u00c9mergents (UVE: Aix-Marseille Univ, Universit\u00e0 di Corsica, IRD 190, Inserm 1207, IRBA)","place":["Marseille, 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