{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:23:35Z","timestamp":1792193015843,"version":"4.4.0"},"reference-count":20,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100009287","name":"NSW Health","doi-asserted-by":"publisher","award":["PRSP 6"],"award-info":[{"award-number":["PRSP 6"]}],"id":[{"id":"10.13039\/501100009287","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["ASM Case Rep"],"published-print":{"date-parts":[[2025,5,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:sec>\n            <jats:title\/>\n            <jats:sec>\n              <jats:title>Background<\/jats:title>\n              <jats:p>\n                Despite successful vaccination programs, many countries are experiencing a marked rise in pertussis cases since 2024, compounded by the emergence of macrolide-resistant\n                <jats:italic toggle=\"yes\">Bordetella pertussis<\/jats:italic>\n                (MRBP). Here, we report the clinical, laboratory, and genomic features of MRBP isolated from a child with severe pertussis.\n              <\/jats:p>\n            <\/jats:sec>\n            <jats:sec>\n              <jats:title>Case Summary<\/jats:title>\n              <jats:p>\n                An 11-week-old term infant with pertussis who required intensive care unit support remained\n                <jats:italic toggle=\"yes\">B. pertussis<\/jats:italic>\n                culture-positive despite azithromycin therapy. Pre- and post-treatment isolates demonstrated phenotypic drug resistance and carried known 23S rRNA macrolide-resistance conferring mutations.\n              <\/jats:p>\n            <\/jats:sec>\n            <jats:sec>\n              <jats:title>Conclusion<\/jats:title>\n              <jats:p>\n                The international spread of macrolide-resistant\n                <jats:italic toggle=\"yes\">B. pertussis<\/jats:italic>\n                warrants the introduction of susceptibility testing for this pathogen.\n              <\/jats:p>\n            <\/jats:sec>\n          <\/jats:sec>","DOI":"10.1128\/asmcr.00093-24","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T09:02:11Z","timestamp":1741683731000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":7,"title":["Microbiological treatment failure associated with macrolide-resistant\n            <i>Bordetella pertussis<\/i>"],"prefix":"10.1128","volume":"1","author":[{"given":"David","family":"Prabhakar","sequence":"first","affiliation":[{"name":"Microbiology and Infectious Diseases, Children's Hospital at Westmead","place":["Sydney, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Winkie","family":"Fong","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases and Microbiology-Public Health, Westmead Hospital, Western Sydney Local Health District","place":["Sydney, Australia"]},{"name":"School of Medical Sciences and Sydney Infectious Diseases Institute (Sydney ID), Faculty of Medicine and Health, The University of Sydney","place":["Sydney, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eby M.","family":"Sim","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases and Microbiology-Public Health, Westmead Hospital, Western Sydney Local Health District","place":["Sydney, Australia"]},{"name":"School of Medical Sciences and Sydney Infectious Diseases Institute (Sydney ID), Faculty of Medicine and Health, The University of Sydney","place":["Sydney, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annaleise R.","family":"Howard-Jones","sequence":"additional","affiliation":[{"name":"Microbiology and Infectious Diseases, Children's Hospital at Westmead","place":["Sydney, Australia"]},{"name":"School of Medical Sciences and Sydney Infectious Diseases Institute (Sydney ID), Faculty of Medicine and Health, The University of Sydney","place":["Sydney, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trang","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, NSW Health Pathology","place":["Sydney, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne","family":"Dempsey","sequence":"additional","affiliation":[{"name":"Microbiology and Infectious Diseases, Children's Hospital at Westmead","place":["Sydney, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4329-5198","authenticated-orcid":true,"given":"Rebecca J.","family":"Rockett","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases and Microbiology-Public Health, Westmead Hospital, Western Sydney Local Health District","place":["Sydney, Australia"]},{"name":"School of Medical Sciences and Sydney Infectious Diseases Institute (Sydney ID), Faculty of Medicine and Health, The University of Sydney","place":["Sydney, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jen","family":"Kok","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases and Microbiology-Public Health, Westmead Hospital, Western Sydney Local Health District","place":["Sydney, Australia"]},{"name":"School of Medical Sciences and Sydney Infectious Diseases Institute (Sydney ID), Faculty of Medicine and Health, The University of Sydney","place":["Sydney, Australia"]},{"name":"Center for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, NSW Health Pathology","place":["Sydney, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon C.-A.","family":"Chen","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases and Microbiology-Public Health, Westmead Hospital, Western Sydney Local Health District","place":["Sydney, Australia"]},{"name":"School of Medical Sciences and Sydney Infectious Diseases Institute (Sydney ID), Faculty of Medicine and Health, The University of Sydney","place":["Sydney, Australia"]},{"name":"Center for Infectious Diseases and Microbiology Laboratory Services, Institute of Clinical Pathology and Medical Research, NSW Health Pathology","place":["Sydney, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander C.","family":"Outhred","sequence":"additional","affiliation":[{"name":"Microbiology and Infectious Diseases, Children's Hospital at Westmead","place":["Sydney, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9261-3650","authenticated-orcid":false,"given":"Vitali","family":"Sintchenko","sequence":"additional","affiliation":[{"name":"Center for Infectious Diseases and Microbiology-Public Health, Westmead Hospital, Western Sydney Local Health District","place":["Sydney, Australia"]},{"name":"School of Medical Sciences and Sydney Infectious Diseases Institute (Sydney ID), Faculty of Medicine and Health, The University of Sydney","place":["Sydney, Australia"]},{"name":"Center for Infectious Diseases and Microbiology Laboratory Services, Institute of 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