{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T15:54:06Z","timestamp":1785426846032,"version":"3.56.0"},"reference-count":17,"publisher":"American Society for Microbiology","issue":"5","license":[{"start":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T00:00:00Z","timestamp":1756771200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T00:00:00Z","timestamp":1756771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["ASM Case Rep"],"published-print":{"date-parts":[[2025,9,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:sec>\n                      <jats:title>Background<\/jats:title>\n                      <jats:p>\n                        Gastrointestinal tuberculosis (GI TB) is an extrapulmonary manifestation of infection with the bacterium\n                        <jats:italic toggle=\"yes\">Mycobacterium tuberculosis<\/jats:italic>\n                        . While GI TB was once considered a rare entity, it has increasing prevalence with the use of immunosuppressive treatments. Diagnosis can be challenging as GI TB can be misdiagnosed as other primary etiologies.\n                      <\/jats:p>\n                    <\/jats:sec>\n                    <jats:sec>\n                      <jats:title>Case Summary<\/jats:title>\n                      <jats:p>Here, we present a case of GI TB in which the patient was immunocompetent and presented with nonspecific symptoms, and an interferon-gamma release assay, which was positive. Subsequent biopsies were performed of the ascending colon, all showing positivity on acid-fast bacilli (AFB, Ziehl-Neelsen) and Fite stains, along with non-caseating granulomas on histopathologic review.<\/jats:p>\n                    <\/jats:sec>\n                    <jats:sec>\n                      <jats:title>Conclusion<\/jats:title>\n                      <jats:p>In the presented case, the patient is immunocompetent. GI TB was diagnosed after histopathologic examination of colonic biopsies. This highlights the importance of having a high index of suspicion for unusual presentations of tuberculosis, especially in patients who come from endemic areas or who might have been exposed recently.<\/jats:p>\n                    <\/jats:sec>\n                  <\/jats:sec>","DOI":"10.1128\/asmcr.00105-24","type":"journal-article","created":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T09:02:40Z","timestamp":1751533360000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["Histopathologic and molecular diagnosis of gastrointestinal tuberculosis in an immunocompetent patient: case report"],"prefix":"10.1128","volume":"1","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-0972-4993","authenticated-orcid":true,"given":"Sashank","family":"Cherukuri","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05wyq9e07","id-type":"ROR","asserted-by":"publisher"}],"name":"Stony Brook University Hospital","place":["Stony Brook, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4188-1823","authenticated-orcid":true,"given":"Emily B.","family":"Huang","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05wyq9e07","id-type":"ROR","asserted-by":"publisher"}],"name":"Stony Brook University Hospital","place":["Stony Brook, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2979-7522","authenticated-orcid":true,"given":"Arthur H.","family":"Totten","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05wyq9e07","id-type":"ROR","asserted-by":"publisher"}],"name":"Stony Brook University Hospital","place":["Stony Brook, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Steinberg","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05wyq9e07","id-type":"ROR","asserted-by":"publisher"}],"name":"Stony Brook University Hospital","place":["Stony Brook, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunjida","family":"Ahmed","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05wyq9e07","id-type":"ROR","asserted-by":"publisher"}],"name":"Stony Brook University Hospital","place":["Stony Brook, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00151-8"},{"key":"e_1_3_3_3_2","first-page":"1761","article-title":"Extrapulmonary tuberculosis: an overview","volume":"72","author":"Golden MP","year":"2005","unstructured":"Golden MP, Vikram HR. 2005. Extrapulmonary tuberculosis: an overview. Am Fam Physician 72:1761\u20131768.","journal-title":"Am Fam Physician"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2021.02.004"},{"key":"e_1_3_3_5_2","volume-title":"Abdominal tuberculosis","author":"Tobin EH","year":"2025","unstructured":"Tobin EH, Khatri AM. 2025. Abdominal tuberculosis. StatPearls."},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-023-02887-0"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jctube.2018.04.003"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2022.994745"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.4103\/sjg.sjg_148_21"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.imj.2023.04.007"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.00065"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/microbiolspec.TNMI7-0014-2016"},{"key":"e_1_3_3_13_2","doi-asserted-by":"crossref","DOI":"10.1007\/978-981-16-9053-2","volume-title":"Tuberculosis of the gastrointestinal system","author":"Sharma M","year":"2022","unstructured":"Sharma M, Sharma K. 2022. Microbiological diagnosis of gastrointestinal tuberculosis. In Sharma V (ed), Tuberculosis of the gastrointestinal system, 1st ed. Springer, Singapore.","edition":"1"},{"key":"e_1_3_3_14_2","volume-title":"Tuberculosis of the gastrointestinal system","author":"Kedia S","year":"2022","unstructured":"Kedia S, Vineet A. 2022. Intestinal tuberculosis: an overview. In Sharma V (ed), Tuberculosis of the gastrointestinal system, 1st ed. Springer, Singapore.","edition":"1"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-62824-z"},{"key":"e_1_3_3_16_2","volume-title":"Tuberculosis of the gastrointestinal system","author":"Nath P","year":"2022","unstructured":"Nath P. 2022. Epidemiology of gastrointestinal tuberculosis. In Sharma V (ed), Tuberculosis of the gastrointestinal system, 1st ed. Springer, Singapore.","edition":"1"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijso.2022.100457"},{"key":"e_1_3_3_18_2","doi-asserted-by":"crossref","DOI":"10.1002\/9781118894903","volume-title":"Pathology of liver diseases","author":"Kanel G","year":"2017","unstructured":"Kanel G. 2017. Chapter 5. Non-viral infectious diseases. In Pathology of liver diseases, 1st ed. John Wiley & Sons, Incorporated.","edition":"1"}],"container-title":["ASM Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/asmcr.00105-24","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/asmcr.00105-24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T17:29:59Z","timestamp":1757438999000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/asmcr.00105-24"}},"subtitle":[],"editor":[{"given":"Carey-Ann D.","family":"Burnham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2025,9,2]]},"references-count":17,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,9,2]]}},"alternative-id":["10.1128\/asmcr.00105-24"],"URL":"https:\/\/doi.org\/10.1128\/asmcr.00105-24","relation":{},"ISSN":["2996-2684"],"issn-type":[{"value":"2996-2684","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,2]]},"assertion":[{"value":"2024-11-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00105-24"}}