{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:19:40Z","timestamp":1785428380366,"version":"3.56.0"},"reference-count":17,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["ASM Case Rep"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:sec>\n                      <jats:title>Background<\/jats:title>\n                      <jats:p>\n                        Invasive fusariosis is rarely reported post-chimeric antigen receptor T-cell (CAR-T) therapy. We herein present a case of cutaneous invasive\n                        <jats:italic toggle=\"yes\">Fusarium<\/jats:italic>\n                        infection and provide a compilation of similar cases documented in the existing literature.\n                      <\/jats:p>\n                    <\/jats:sec>\n                    <jats:sec>\n                      <jats:title>Case Summary<\/jats:title>\n                      <jats:p>\n                        A 61-year-old woman with relapsed refractory diffuse large B-cell lymphoma and secondary hemophagocytic lymphohistiocytosis received CD19-CAR-T therapy. She developed grade 1 cytokine release syndrome (CRS) and grade 3 immune effector cell-associated neurotoxicity syndrome (ICANS), requiring dexamethasone and anakinra. Twenty-five days after CAR-T, she developed bilateral proximal thigh nodular lesions. Skin biopsy revealed hyphal structures with hyphal structures, and culture revealed\n                        <jats:italic toggle=\"yes\">Fusarium<\/jats:italic>\n                        species. Treatment with liposomal amphotericin B, voriconazole, and terbinafine followed by voriconazole and terbinafine led to clinical improvement.\n                      <\/jats:p>\n                    <\/jats:sec>\n                    <jats:sec>\n                      <jats:title>Conclusion<\/jats:title>\n                      <jats:p>\n                        Though rare, healthcare providers should maintain an index of suspicion for\n                        <jats:italic toggle=\"yes\">Fusarium<\/jats:italic>\n                        infections in recipients of cellular therapies with risk factors.\n                      <\/jats:p>\n                    <\/jats:sec>\n                  <\/jats:sec>","DOI":"10.1128\/asmcr.00117-24","type":"journal-article","created":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T09:00:14Z","timestamp":1746694814000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["Invasive fusariosis after CD19 chimeric antigen receptor T-cell therapy"],"prefix":"10.1128","volume":"1","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7110-8885","authenticated-orcid":true,"given":"Rita","family":"Wilson Dib","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0457zbj98","id-type":"ROR","asserted-by":"publisher"}],"name":"Infectious Diseases Section, Department of Medicine, The University of Oklahoma Health Sciences Center","place":["Oklahoma City, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annoir","family":"Shayya","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/00hqkan37","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Hematology & Medical Oncology, Lebanese American University-Rizk Hospital","place":["Beirut, Lebanon"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily A.","family":"Siegrist","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0457zbj98","id-type":"ROR","asserted-by":"publisher"}],"name":"Infectious Diseases Section, Department of Medicine, The University of Oklahoma Health Sciences Center","place":["Oklahoma City, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Alkozah","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0457zbj98","id-type":"ROR","asserted-by":"publisher"}],"name":"Infectious Diseases Section, Department of Medicine, The University of Oklahoma Health Sciences Center","place":["Oklahoma City, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Scott","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0457zbj98","id-type":"ROR","asserted-by":"publisher"}],"name":"Infectious Diseases Section, Department of Medicine, The University of Oklahoma Health Sciences Center","place":["Oklahoma City, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Henao-Cordero","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0457zbj98","id-type":"ROR","asserted-by":"publisher"}],"name":"Infectious Diseases Section, Department of Medicine, The University of Oklahoma Health Sciences Center","place":["Oklahoma City, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cindy","family":"McCloskey","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Oklahoma University Health Sciences Center","place":["Oklahoma City, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Speckman","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Oklahoma University Health Sciences Center","place":["Oklahoma City, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey D.","family":"McBride","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0457zbj98","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Pathology, University of Oklahoma Health Sciences Center","place":["Oklahoma City, USA"]},{"id":[{"id":"https:\/\/ror.org\/0457zbj98","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Dermatology, University of Oklahoma Health Sciences Center","place":["Oklahoma City, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Holter-Chakrabarty","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0457zbj98","id-type":"ROR","asserted-by":"publisher"}],"name":"Hematology-Oncology Section, Department of Medicine, University of Oklahoma Health Sciences Center","place":["Oklahoma City, 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