{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T13:29:05Z","timestamp":1777555745019,"version":"3.51.4"},"reference-count":11,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2003,3,1]],"date-time":"2003-03-01T00:00:00Z","timestamp":1046476800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Vaccine Immunol"],"published-print":{"date-parts":[[2003,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>Mixed connective tissue disease is an overlap syndrome characterized by features of different systemic autoimmune diseases and a high titer of U1-snRNP antibodies. We examine here the autoantibodies to nucleoporin p62 in a severe case of mixed connective tissue disease in a young male patient. Thus far, p62 antibodies have mainly been described in cases of primary biliary cirrhosis. We speculate that the presence of p62 antibodies is an indication of a poor prognosis in connective tissue disorders.<\/jats:p>","DOI":"10.1128\/cdli.10.2.329-331.2003","type":"journal-article","created":{"date-parts":[[2003,3,7]],"date-time":"2003-03-07T20:51:51Z","timestamp":1047070311000},"page":"329-331","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":4,"title":["Nucleoporin p62 Antibodies in a Case of Mixed Connective Tissue Disease"],"prefix":"10.1128","volume":"10","author":[{"given":"Doris M.","family":"Kraemer","sequence":"first","affiliation":[{"name":"Medizinische Poliklinik, University of Wurzburg, 97070 Wurzburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael R.","family":"Kraus","sequence":"additional","affiliation":[{"name":"Medizinische Poliklinik, University of Wurzburg, 97070 Wurzburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Kneitz","sequence":"additional","affiliation":[{"name":"Medizinische Poliklinik, University of Wurzburg, 97070 Wurzburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Peter","family":"Tony","sequence":"additional","affiliation":[{"name":"Medizinische Poliklinik, University of Wurzburg, 97070 Wurzburg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","first-page":"17","volume":"55","year":"1991","unstructured":"Carmo-Fonseca, M., H. 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