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The production of IFN-\u03b3 was largely dependent on IL-12. These data establish that pathogenic leptospires can stimulate the production of type I cytokines involved in cellular immunity.<\/jats:p>","DOI":"10.1128\/cdli.10.2.332-335.2003","type":"journal-article","created":{"date-parts":[[2003,3,7]],"date-time":"2003-03-07T20:51:51Z","timestamp":1047070311000},"page":"332-335","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":18,"title":["Interleukin 12 in Part Regulates Gamma Interferon Release in Human Whole Blood Stimulated with<i>Leptospira interrogans<\/i>"],"prefix":"10.1128","volume":"10","author":[{"given":"Maaike","family":"de Fost","sequence":"first","affiliation":[{"name":"Laboratory of Experimental Internal Medicine"},{"name":"Department of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam"},{"name":"WHO\/FAO Collaborating Centre for Reference and Research on Leptospirosis, Royal Tropical Institute, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudy A.","family":"Hartskeerl","sequence":"additional","affiliation":[{"name":"Laboratory of Experimental Internal Medicine"},{"name":"Department of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam"},{"name":"WHO\/FAO Collaborating Centre for Reference and Research on Leptospirosis, Royal Tropical Institute, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martijn R.","family":"Groenendijk","sequence":"additional","affiliation":[{"name":"Laboratory of Experimental Internal Medicine"},{"name":"Department of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam"},{"name":"WHO\/FAO Collaborating Centre for Reference and Research on Leptospirosis, Royal Tropical Institute, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"van der Poll","sequence":"additional","affiliation":[{"name":"Laboratory of Experimental Internal Medicine"},{"name":"Department of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam"},{"name":"WHO\/FAO Collaborating Centre for Reference and Research on Leptospirosis, Royal Tropical Institute, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1146\/annurev.immunol.15.1.749","volume":"15","year":"1997","unstructured":"Boehm, U., T. 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