{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T02:10:12Z","timestamp":1790475012623,"version":"4.1.0"},"reference-count":19,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2002,3,1]],"date-time":"2002-03-01T00:00:00Z","timestamp":1014940800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Vaccine Immunol"],"published-print":{"date-parts":[[2002,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>We describe two unusual cases of congenital toxoplasmosis, one occurring after preconception maternal infection with cervical adenopathies and the other occurring after maternal infection at the very end of pregnancy with maternal seronegativity at delivery. These documented cases of congenital toxoplasmosis demonstrate the value of extending the serologic monitoring period during pregnancy, according to the individual clinical context.<\/jats:p>","DOI":"10.1128\/cdli.9.2.489-490.2002","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T09:58:35Z","timestamp":1027763915000},"page":"489-490","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":4,"title":["Preconception Seroconversion and Maternal Seronegativity at Delivery Do Not Rule Out the Risk of Congenital Toxoplasmosis"],"prefix":"10.1128","volume":"9","author":[{"given":"C.","family":"Chemla","sequence":"first","affiliation":[{"name":"Divisions of Parasitology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Villena","sequence":"additional","affiliation":[{"name":"Divisions of Parasitology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Aubert","sequence":"additional","affiliation":[{"name":"Divisions of Parasitology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Hornoy","sequence":"additional","affiliation":[{"name":"Imagery"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Dupouy","sequence":"additional","affiliation":[{"name":"Pediatrics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Leroux","sequence":"additional","affiliation":[{"name":"Pediatrics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. P.","family":"Bory","sequence":"additional","affiliation":[{"name":"Gynecology, Reims Toxoplasmosis Group, Laboratoire de Parasitologie-Mycologie, Centre Hospitalier Universitaire, EA2070, IFR 53, Reims 51092, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. M.","family":"Pinon","sequence":"additional","affiliation":[{"name":"Divisions of Parasitology"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","first-page":"855","volume":"31","year":"1984","unstructured":"Couvreur, J., G. Desmonts, and D. Aron Rosa. 1984. Le pronostic oculaire de la toxoplasmose cong\u00e9nitale: le r\u00f4le du traitement. Ann. Exp. Pediatr. (Paris)31:855-858.","journal-title":"Ann. Exp. Pediatr. (Paris)"},{"key":"e_1_3_2_3_2","first-page":"1445","volume":"19","year":"1990","unstructured":"Desmonts, G., J. Couvreur, and P. Thulliez. 1990. Congenital toxoplasmosis: five cases with mother-to-child transmission of pre-pregnancy infection. Presse Med.19:1445-1449.","journal-title":"Presse Med."},{"key":"e_1_3_2_4_2","doi-asserted-by":"crossref","first-page":"383","DOI":"10.3109\/00365549609037924","volume":"28","year":"1996","unstructured":"Foudrinier, F., D. Aubert, D. Puygauthier-Toubas, C. Rouger, I. Beguinot, P. Halbout, P. Lemaire, C. Marx-Chemla, and J. M. Pinon. 1996. Detection of Toxoplasma gondii in immunodeficient subject by gene amplification: influence of therapeutics. Scand. J. Infect. Dis.28:383-386.","journal-title":"Scand. J. Infect. Dis."},{"key":"e_1_3_2_5_2","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/S0002-9378(99)70311-X","volume":"181","year":"1999","unstructured":"Foulon, W., J. M. Pinon, B. Stray-Pedersen, A. Pollak, M. Lappalainen, A. Decoster, I. Villena, P. A. Jenun, M. Hayde, and A. Naessens. 1999. Prenatal diagnosis of congenital toxoplasmosis: a multicenter evaluation of different diagnostic parameters. Am. J. Obstet. Exp. Gynecol.181:843-847.","journal-title":"Am. J. Obstet. Exp. Gynecol."},{"key":"e_1_3_2_6_2","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1002\/(SICI)1097-0223(199711)17:11<1047::AID-PD192>3.0.CO;2-Q","volume":"17","year":"1997","unstructured":"Hezard, N., C. Marx-Chemla, F. Foudrinier, I. Villena, C. Quereux, B. Leroux, D. Dupouy, M. Talmud, and J. M. Pinon. 1997. Prenatal diagnosis of congenital toxoplasmosis in 261 pregnancies. Prenat. Diagn.17:1047-1054.","journal-title":"Prenat. Diagn."},{"key":"e_1_3_2_7_2","first-page":"387.","volume":"20","year":"1991","unstructured":"Marty, P., Y. Le Fichoux, A. Deville, and H. Forrest. 1991. Toxoplasmose cong\u00e9nitale et toxoplasmose ganglionnaire maternelle pr\u00e9conceptionnelle. Presse Med.20:387.","journal-title":"Presse Med."},{"key":"e_1_3_2_8_2","first-page":"367","volume":"19","year":"1990","unstructured":"Marx-Chemla, C., D. Pugauthier-Toubas, F. Foudrinier, P. H. Dorangeon, J. Leulier, C. Quereux, B. Leroux, and J. M. Pinon. 1990. Should the immunological control of toxoplasmosis seronegative pregnant women cease at delivery? Presse Med.19:367-368.","journal-title":"Presse Med."},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.34.3.579-583.1996"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.6.2267-2271.2001"},{"key":"e_1_3_2_11_2","first-page":"223","volume":"4","year":"1986","unstructured":"Pinon, J. M., H. Thoannes, P. Pouletty, J. Poirriez, J. Damiens, and P. Pelletier. 1986. Detection of IgA specific for toxoplasmosis in serum and cerebrospinal fluid using a non-enzymatic IgA-capture assay. Diagn. Immunol.4:223-227.","journal-title":"Diagn. Immunol."},{"key":"e_1_3_2_12_2","first-page":"179","volume":"24","year":"1995","unstructured":"Pons, J. C., C. Sigrand, L. Grangeot-Keros, R. Frydman, and P. Thulliez. 1995. Congenital toxoplasmosis: mother-to-fetus transmission of pre-pregnancy infection. Presse Med.24:179-182.","journal-title":"Presse Med."},{"key":"e_1_3_2_13_2","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0022-1759(85)90306-0","volume":"76","year":"1985","unstructured":"Pouletty, P., J. Kadouche, M. Garcia-Gonzales, E. Mihaesco, G. Desmonts, P. Thulliez, H. Thoannes, and J. M. Pinon. 1985. An anti-human \u03bc chain monoclonal antibody: use for detection of IgM antibodies to Toxoplasma gondii by reverse immunosorbent assay. J. Immunol. Methods76:289-298.","journal-title":"J. Immunol. Methods"},{"key":"e_1_3_2_14_2","first-page":"140","year":"1995","unstructured":"Remington, J. S., R. McLeod, and G. Desmonts. 1995. Toxoplasmosis, p. 140-268. In J. S. Remington and J. O. Klein (ed.), Infectious diseases of the fetus and newborn infant, 4th ed. W. B. Saunders, Philadelphia, Pa.","journal-title":"Infectious diseases of the fetus and newborn infant"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.9.2893-2898.1999"},{"key":"e_1_3_2_16_2","first-page":"296","volume":"97","year":"2001","unstructured":"Romand, S., M. Wallon, J. Franck, P. Thulliez, F. Peyron, and H. Dumon. 2001. Prenatal diagnosis using polymerase chain reaction on amniotic fluid for congenital toxoplasmosis. Obstet. Gynecol.97:296-300.","journal-title":"Obstet. Gynecol."},{"key":"e_1_3_2_17_2","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1002\/(SICI)1097-0223(1998100)18:10<1079::AID-PD391>3.0.CO;2-E","volume":"18","year":"1998","unstructured":"Villena, I., C. Chemla, C. Quereux, D. Dupouy, B. Leroux, F. Foudrinier, and J. M. Pinon. Prenatal diagnosis of congenital toxoplasmosis transmitted by an immunocompetent woman infected before conception. 1998. Prenat. Diagn.18:1079-1081.","journal-title":"Prenat. Diagn."},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.11.3487-3490.1999"},{"key":"e_1_3_2_19_2","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1093\/clinids\/23.5.1055","volume":"23","year":"1996","unstructured":"Vogel, N., M. Kirisits, E. Michael, H. Bach, M. Hostetter, K. Boyer, R. Simpson, E. Holfels, J. Hopkins, D. Mack, M. B. Metz, C. N. Swisher, D. Patel, N. Roizen, L. Stein, S. Withers, E. Mui, C. Egwuagu, J. Remington, R. Dorfman, and R. McLeod. 1996. Congenital toxoplasmosis transmitted from an immunologically competent mother infected before conception. Clin. Infect. Dis.23:1055-1060.","journal-title":"Clin. Infect. Dis."},{"key":"e_1_3_2_20_2","first-page":"566","volume":"28","year":"1999","unstructured":"Wirden, M., F. Botterel, S. Romand, G. Ithier, and P. Bour\u00e9e. 1999. Congenital toxoplasmosis following primary maternal infection acquired during late pregnancy: relevance of serological screening after delivery. J. Gynecol. Biol. Reprod.28:566-567.","journal-title":"J. Gynecol. Biol. Reprod."}],"container-title":["Clinical and Vaccine Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/CDLI.9.2.489-490.2002","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/CDLI.9.2.489-490.2002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T20:31:40Z","timestamp":1627590700000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/CDLI.9.2.489-490.2002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,3]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2002,3]]}},"alternative-id":["10.1128\/CDLI.9.2.489-490.2002"],"URL":"https:\/\/doi.org\/10.1128\/cdli.9.2.489-490.2002","relation":{},"ISSN":["1556-6811","1556-679X"],"issn-type":[{"value":"1556-6811","type":"print"},{"value":"1556-679X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,3]]},"assertion":[{"value":"2001-08-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2001-12-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}