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Although recent studies highlight the recovery of\n                      <jats:italic>E. dispar<\/jats:italic>\n                      and\n                      <jats:italic>E. moshkovskii<\/jats:italic>\n                      from patients with gastrointestinal symptoms, there is still no convincing evidence of a causal link between the presence of these two species and the symptoms of the host. New approaches to the identification of\n                      <jats:italic>E. histolytica<\/jats:italic>\n                      are based on detection of\n                      <jats:italic>E. histolytica<\/jats:italic>\n                      -specific antigen and DNA in stool and other clinical samples. Several molecular diagnostic tests, including conventional and real-time PCR, have been developed for the detection and differentiation of\n                      <jats:italic>E. histolytica<\/jats:italic>\n                      ,\n                      <jats:italic>E. dispar<\/jats:italic>\n                      , and\n                      <jats:italic>E. moshkovskii<\/jats:italic>\n                      in clinical samples. The purpose of this review is to discuss different methods that exist for the identification of\n                      <jats:italic>E. histolytica<\/jats:italic>\n                      ,\n                      <jats:italic>E. dispar<\/jats:italic>\n                      , and\n                      <jats:italic>E. moshkovskii<\/jats:italic>\n                      which are available to the clinical diagnostic laboratory. To address the need for a specific diagnostic test for amebiasis, a substantial amount of work has been carried out over the last decade in different parts of the world. The molecular diagnostic tests are increasingly being used for both clinical and research purposes. In order to minimize undue treatment of individuals infected with other species of\n                      <jats:italic>Entamoeba<\/jats:italic>\n                      such as\n                      <jats:italic>E. dispar<\/jats:italic>\n                      and\n                      <jats:italic>E. moshkovskii<\/jats:italic>\n                      , efforts have been made for specific diagnosis of\n                      <jats:italic>E. histolytica infection<\/jats:italic>\n                      and not to treat based simply on the microscopic examination of\n                      <jats:italic>Entamoeba<\/jats:italic>\n                      species in the stool. The incorporation of many new technologies into the diagnostic laboratory will lead to a better understanding of the public health problem and measures to control the disease.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1128\/cmr.00004-07","type":"journal-article","created":{"date-parts":[[2007,7,13]],"date-time":"2007-07-13T13:19:33Z","timestamp":1184332773000},"page":"511-532","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":380,"title":["Laboratory Diagnostic Techniques for\n                    <i>Entamoeba<\/i>\n                    Species"],"prefix":"10.1128","volume":"20","author":[{"given":"R.","family":"Fotedar","sequence":"first","affiliation":[{"name":"St. Vincent's Hospital, Department of Microbiology, Sydney, Australia"},{"name":"University of Technology Sydney, Institute for the Biotechnology of Infectious Diseases, Broadway, Australia"},{"name":"University of Technology Sydney, Department of Medical and Molecular Biosciences, Broadway, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Stark","sequence":"additional","affiliation":[{"name":"St. Vincent's Hospital, Department of Microbiology, Sydney, Australia"},{"name":"University of Technology Sydney, Institute for the Biotechnology of Infectious Diseases, Broadway, Australia"},{"name":"University of Technology Sydney, Department of Medical and Molecular Biosciences, Broadway, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Beebe","sequence":"additional","affiliation":[{"name":"St. Vincent's Hospital, Department of Microbiology, Sydney, Australia"},{"name":"University of Technology Sydney, Institute for the Biotechnology of Infectious Diseases, Broadway, Australia"},{"name":"University of Technology Sydney, Department of Medical and Molecular Biosciences, Broadway, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Marriott","sequence":"additional","affiliation":[{"name":"St. Vincent's Hospital, Department of Microbiology, Sydney, Australia"},{"name":"University of Technology Sydney, Institute for the Biotechnology of Infectious Diseases, Broadway, Australia"},{"name":"University of Technology Sydney, Department of Medical and Molecular Biosciences, Broadway, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Ellis","sequence":"additional","affiliation":[{"name":"St. Vincent's Hospital, Department of Microbiology, Sydney, Australia"},{"name":"University of Technology Sydney, Institute for the Biotechnology of Infectious Diseases, Broadway, Australia"},{"name":"University of Technology Sydney, Department of Medical and Molecular Biosciences, Broadway, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Harkness","sequence":"additional","affiliation":[{"name":"St. Vincent's Hospital, Department of Microbiology, Sydney, Australia"},{"name":"University of Technology Sydney, Institute for the Biotechnology of Infectious Diseases, Broadway, Australia"},{"name":"University of Technology Sydney, Department of Medical and Molecular Biosciences, Broadway, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1998.59.431"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.6.2344-2347.2000"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1993.48.58"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197707000-00003"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197707000-00004"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(95)90488-3"},{"key":"e_1_3_1_8_2","first-page":"285","volume":"28","year":"1997","unstructured":"Aguirre, A., S. 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