{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T07:26:59Z","timestamp":1792740419385,"version":"4.5.0"},"reference-count":469,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Microbiol Rev"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>\n                    Acute\n                    <jats:named-content content-type=\"genus-species\">Trypanosoma cruzi<\/jats:named-content>\n                    infections can be asymptomatic, but chronically infected individuals can die of Chagas' disease. The transfer of the parasite mitochondrial kinetoplast DNA (kDNA) minicircle to the genome of chagasic patients can explain the pathogenesis of the disease; in cases of Chagas' disease with evident cardiomyopathy, the kDNA minicircles integrate mainly into retrotransposons at several chromosomes, but the minicircles are also detected in coding regions of genes that regulate cell growth, differentiation, and immune responses. An accurate evaluation of the role played by the genotype alterations in the autoimmune rejection of self-tissues in Chagas' disease is achieved with the cross-kingdom chicken model system, which is refractory to\n                    <jats:named-content content-type=\"genus-species\">T. cruzi<\/jats:named-content>\n                    infections. The inoculation of\n                    <jats:named-content content-type=\"genus-species\">T. cruzi<\/jats:named-content>\n                    into embryonated eggs prior to incubation generates parasite-free chicks, which retain the kDNA minicircle sequence mainly in the macrochromosome coding genes. Crossbreeding transfers the kDNA mutations to the chicken progeny. The kDNA-mutated chickens develop severe cardiomyopathy in adult life and die of heart failure. The phenotyping of the lesions revealed that cytotoxic CD45, CD8\n                    <jats:sup>+<\/jats:sup>\n                    \u03b3\u03b4, and CD8\u03b1\n                    <jats:sup>+<\/jats:sup>\n                    T lymphocytes carry out the rejection of the chicken heart. These results suggest that the inflammatory cardiomyopathy of Chagas' disease is a genetically driven autoimmune disease.\n                  <\/jats:p>","DOI":"10.1128\/cmr.00063-10","type":"journal-article","created":{"date-parts":[[2011,7,6]],"date-time":"2011-07-06T18:24:39Z","timestamp":1309976679000},"page":"592-630","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":194,"title":["Pathogenesis of Chagas' Disease: Parasite Persistence and Autoimmunity"],"prefix":"10.1128","volume":"24","author":[{"given":"Antonio R. L.","family":"Teixeira","sequence":"first","affiliation":[{"name":"Chagas Disease Multidisciplinary Research Laboratory, Faculty of Medicine, University of Brasilia, 70910900 Brasilia, Federal District, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana M.","family":"Hecht","sequence":"additional","affiliation":[{"name":"Chagas Disease Multidisciplinary Research Laboratory, Faculty of Medicine, University of Brasilia, 70910900 Brasilia, Federal District, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria C.","family":"Guimaro","sequence":"additional","affiliation":[{"name":"Chagas Disease Multidisciplinary Research Laboratory, Faculty of Medicine, University of Brasilia, 70910900 Brasilia, Federal District, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro O.","family":"Sousa","sequence":"additional","affiliation":[{"name":"Chagas Disease Multidisciplinary Research Laboratory, Faculty of Medicine, University of Brasilia, 70910900 Brasilia, Federal District, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadjar","family":"Nitz","sequence":"additional","affiliation":[{"name":"Chagas Disease Multidisciplinary Research Laboratory, Faculty of Medicine, University of Brasilia, 70910900 Brasilia, Federal District, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2005.03.033"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000051866"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkn874"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.71.6.1255"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-6851(01)00245-6"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004280000319"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46651991000600004"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2007.03356.x"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkj108"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1086\/651608"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0900852"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761999000700023"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-78267-6_4"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.8.8.809"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20041408"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro1249"},{"key":"e_1_3_2_18_2","first-page":"219","article-title":"Chagas disease and neuronal alterations at the Auerbach's plexus.","volume":"8","author":"Andrade S. G.","year":"1966","unstructured":"Andrade S. G. Andrade Z. A. . 1966. Chagas disease and neuronal alterations at the Auerbach's plexus.. Rev. Inst. Med. Trop. Sao Paulo 8:219\u2013224.","journal-title":"Rev. Inst. Med. Trop. Sao Paulo"},{"key":"e_1_3_2_19_2","first-page":"279","article-title":"Pathogenesis of Chagas' chronic myocarditis; importance of ischemic lesions","volume":"45","author":"Andrade Z. A.","year":"1955","unstructured":"Andrade Z. A. Andrade S. G. . 1955. Pathogenesis of Chagas' chronic myocarditis; importance of ischemic lesions. Arq. Bras. Med. 45:279\u2013288.","journal-title":"Arq. Bras. Med."},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200205110"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2006.01.017"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1086\/506624"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-2478(01)00283-8"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0066-782X2003001200008"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762009000900004"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cytogfr.2008.08.002"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1086\/345882"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-8-391"},{"key":"e_1_3_2_29_2","first-page":"E908","article-title":"Altered energy balance and cytokine gene expression in a murine model of chronic infection with Toxoplasma gondii","volume":"272","author":"Arsenijevic D.","year":"1997","unstructured":"Arsenijevic D. Girardier L. Seydoux J. Chang H. R. Dulloo A. G. . 1997. Altered energy balance and cytokine gene expression in a murine model of chronic infection with Toxoplasma gondii . Am. J. Physiol. 272:E908\u2013E917.","journal-title":"Am. J. Physiol."},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1110289"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0307312101"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1645\/GE-1309.1"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.290.5493.972"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2009.06.004"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.09.068"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1179\/136485908X311740"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652008000200001"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1984.33.30"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.4.2644"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri2654"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0014571"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(91)90151-U"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652000000300009"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.2307\/3275869"},{"key":"e_1_3_2_45_2","volume-title":"Trypanosoma cruzi and Chagas disease","author":"Brener Z.","year":"2000","unstructured":"Brener Z. Andrade Z. A. Barral-Neto M. . 2000. Trypanosoma cruzi and Chagas disease, 2nd ed. Guanabara Koogan, Rio de Janeiro, Brazil.","edition":"2"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-6851(98)00080-2"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2008.02.009"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V34895"},{"key":"e_1_3_2_49_2","doi-asserted-by":"crossref","unstructured":"Brown E. L. . 18 December 2009 posting date. Seroprevalence of Trypanosoma cruzi among eleven potential reservoir species from six states across the Southern United States. Vector Borne Zoonotic Dis. doi:10.1089\/vbz.2009.0009","DOI":"10.1089\/vbz.2009.0009"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1462-5822.2002.00226.x"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-011-8095-5"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/17.17.4975"},{"key":"e_1_3_2_53_2","volume-title":"Emerging Chagas disease","author":"Campbell D. C.","year":"2009","unstructured":"Campbell D. C. Sturm N. R. . 2009. Trypanosoma cruzi nuclear DNA and its correlation with the parasite lifecycle, p. 70\u201382.In Teixeira A. R. L. Vinaud M. C. Castro A. M. . (ed.), Emerging Chagas disease, 1st ed. Bentham Science Publishers, New York, NY.","edition":"1"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2003.09.005"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.63.3.751-756.1995"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2008.04.010"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.2307\/3280909"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2613.2008.00592.x"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-52-2-297"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2008.10.002"},{"key":"e_1_3_2_61_2","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2009.0161"},{"key":"e_1_3_2_62_2","doi-asserted-by":"publisher","DOI":"10.1186\/1745-6150-5-7"},{"key":"e_1_3_2_63_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/168.4.986"},{"key":"e_1_3_2_64_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761909000200008"},{"key":"e_1_3_2_65_2","first-page":"255","article-title":"Nova entidade m\u00f3rbida do homem","volume":"1","author":"Chagas C","year":"1910","unstructured":"Chagas C . 1910. Nova entidade m\u00f3rbida do homem. Arch. Soc. M\u00e9d. Cirurg. S. Paulo 1:255\u2013292.","journal-title":"Arch. Soc. M\u00e9d. Cirurg. S. Paulo"},{"key":"e_1_3_2_66_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761911000200003"},{"key":"e_1_3_2_67_2","first-page":"305","article-title":"Sobre um trypanosoma do tat\u00fa. Tatusia novemcineta, transmitido pelo Triatoma geniculata Latr. (1811). Possibilidade de ser o tat\u00fa um deposit\u00e1rio do Trypanosoma cruzi no mundo exterior.","volume":"26","author":"Chagas C","year":"1912","unstructured":"Chagas C . 1912. Sobre um trypanosoma do tat\u00fa. Tatusia novemcineta, transmitido pelo Triatoma geniculata Latr. (1811). Possibilidade de ser o tat\u00fa um deposit\u00e1rio do Trypanosoma cruzi no mundo exterior. Bras. Med. 26:305\u2013306.","journal-title":"Bras. Med"},{"key":"e_1_3_2_68_2","first-page":"58","article-title":"Estado actual da tripanossom\u00edase Americana","volume":"5","author":"Chagas C","year":"1934","unstructured":"Chagas C . 1934. Estado actual da tripanossom\u00edase Americana. Rev. Biol. Hyg. 5:58\u201364.","journal-title":"Rev. Biol. Hyg."},{"key":"e_1_3_2_69_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761916000200003"},{"key":"e_1_3_2_70_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761922000100001"},{"key":"e_1_3_2_71_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetimm.2004.08.010"},{"key":"e_1_3_2_72_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-09-018655"},{"key":"e_1_3_2_73_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature07013"},{"key":"e_1_3_2_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2776(08)00604-4"},{"key":"e_1_3_2_75_2","doi-asserted-by":"publisher","DOI":"10.1006\/cyto.1995.0088"},{"key":"e_1_3_2_76_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1192009"},{"key":"e_1_3_2_77_2","first-page":"113","article-title":"Transmission of chagasic infection by oral route in the natural history of Chagas disease","volume":"39","author":"Coura J. R","year":"2006","unstructured":"Coura J. R . 2006. Transmission of chagasic infection by oral route in the natural history of Chagas disease. Rev. Soc. Bras. Med. Trop. 39(Suppl. 3):113\u2013117.","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"e_1_3_2_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-4922(01)02200-0"},{"key":"e_1_3_2_79_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkp703"},{"key":"e_1_3_2_80_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1550-7408.1979.tb04203.x"},{"key":"e_1_3_2_81_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2009.02.024"},{"key":"e_1_3_2_82_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2003.07.026"},{"key":"e_1_3_2_83_2","doi-asserted-by":"publisher","DOI":"10.1080\/08916930500485002"},{"key":"e_1_3_2_84_2","doi-asserted-by":"publisher","DOI":"10.3109\/08916930109007383"},{"key":"e_1_3_2_85_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762009000900032"},{"key":"e_1_3_2_86_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.8.3541"},{"key":"e_1_3_2_87_2","doi-asserted-by":"publisher","DOI":"10.2307\/3280477"},{"key":"e_1_3_2_88_2","doi-asserted-by":"publisher","DOI":"10.2307\/3279722"},{"key":"e_1_3_2_89_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2004.01.010"},{"key":"e_1_3_2_90_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0361-9230(00)00326-9"},{"key":"e_1_3_2_91_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000604"},{"key":"e_1_3_2_92_2","doi-asserted-by":"publisher","DOI":"10.1080\/08916930802167902"},{"key":"e_1_3_2_93_2","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00297-07"},{"key":"e_1_3_2_94_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.02.012"},{"key":"e_1_3_2_95_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2003.06.015"},{"key":"e_1_3_2_96_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2008.01.001"},{"key":"e_1_3_2_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2006.11.176"},{"key":"e_1_3_2_98_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2004.08.023"},{"key":"e_1_3_2_99_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01459-08"},{"key":"e_1_3_2_100_2","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(86)90181-X"},{"key":"e_1_3_2_101_2","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.107.071621"},{"key":"e_1_3_2_102_2","doi-asserted-by":"publisher","DOI":"10.1638\/2007-0120.1"},{"key":"e_1_3_2_103_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000417"},{"key":"e_1_3_2_104_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762009000900014"},{"key":"e_1_3_2_105_2","first-page":"89","article-title":"DNA-containing organelles in pathogenic protozoa: a review","volume":"2","author":"de Souza W.","year":"2008","unstructured":"de Souza W. Cavalcanti D. P. . 2008. DNA-containing organelles in pathogenic protozoa: a review. Trends Cell. Mol. Biol. 2:89\u2013104.","journal-title":"Trends Cell. Mol. Biol."},{"key":"e_1_3_2_106_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1550-7408.1974.tb03615.x"},{"key":"e_1_3_2_107_2","doi-asserted-by":"publisher","DOI":"10.1645\/0022-3395(2000)086[1035:ASOHII]2.0.CO;2"},{"key":"e_1_3_2_108_2","first-page":"181","article-title":"Non-receptivity of the domestic pigeon to the Schizotrypanum infection. Mem","volume":"40","author":"Dias E","year":"1944","unstructured":"Dias E . 1944. Non-receptivity of the domestic pigeon to the Schizotrypanum infection. Mem. Inst. Oswaldo Cruz 40:181.","journal-title":"Inst. Oswaldo Cruz"},{"key":"e_1_3_2_109_2","first-page":"255","article-title":"IV. Colombia, Venezuela and the Guianas. Rev. Bras. Malariol.","volume":"4","author":"Dias E","year":"1952","unstructured":"Dias E . 1952. Chagas' disease in the Americas. IV. Colombia, Venezuela and the Guianas. Rev. Bras. Malariol. Doencas Trop. 4:255\u2013280.","journal-title":"Doencas Trop."},{"key":"e_1_3_2_110_2","first-page":"131","article-title":"VII. Chile. Rev. Bras. Malariol.","volume":"5","author":"Dias E","year":"1953","unstructured":"Dias E . 1953. Chagas disease in the Americas. VII. Chile. Rev. Bras. Malariol. Doencas Trop. 5:131\u2013136.","journal-title":"Doencas Trop."},{"key":"e_1_3_2_111_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.14.6.1035"},{"key":"e_1_3_2_112_2","volume-title":"Emerging Chagas disease","author":"Dias J. C. P.","year":"2009","unstructured":"Dias J. C. P. Schofiel J. C. . 2009. History of Chagas disease as a public health problem in Latin America, p. 1\u20139.In Teixeira A. R. L. Vinaud M. C. Castro A. M. . (ed.), Emerging Chagas disease, 1st ed. Bentham Science Publishers, New York, NY.","edition":"1"},{"key":"e_1_3_2_113_2","volume-title":"Emerging Chagas disease","author":"Diotaiuti L","year":"2009","unstructured":"Diotaiuti L . 2009. Triatomine-vector of Trypanosoma cruzi infection, p. 24\u201339.In Teixeira A. R. L. Vinaud M. C. Castro A. M. . (ed.), Emerging Chagas disease, 1st ed. Bentham Science Publishers, New York, NY.","edition":"1"},{"key":"e_1_3_2_114_2","doi-asserted-by":"publisher","DOI":"10.1645\/0022-3395(2002)088[0409:AAHPOT]2.0.CO;2"},{"key":"e_1_3_2_115_2","unstructured":"Dittmar K. Jansen A. M. Ara\u00fajo A. Reinhard K. . 2003. Molecular diagnosis of prehistoric T. cruzi in the Texas-Coahuila border region. Thirteenth Annual Meeting of the Paleopathology Association Tempe Arizona. Paleopathol. News 1:4."},{"key":"e_1_3_2_116_2","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-50-5-1943"},{"key":"e_1_3_2_117_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2010.05.010"},{"key":"e_1_3_2_118_2","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.108.096636"},{"key":"e_1_3_2_119_2","doi-asserted-by":"publisher","DOI":"10.1038\/32033"},{"key":"e_1_3_2_120_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2008.01.008"},{"key":"e_1_3_2_121_2","doi-asserted-by":"publisher","DOI":"10.1006\/expr.2000.4509"},{"key":"e_1_3_2_122_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3083.1997.d01-362.x"},{"key":"e_1_3_2_123_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.240240406"},{"key":"e_1_3_2_124_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1550-7408.1982.tb05427.x"},{"key":"e_1_3_2_125_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-6851(00)00349-2"},{"key":"e_1_3_2_126_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1112631"},{"key":"e_1_3_2_127_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-706X(01)00202-9"},{"key":"e_1_3_2_128_2","doi-asserted-by":"crossref","unstructured":"Epting C. L. Coates B. M. Engman D. M. . 18 June 2010 posting date. Molecular mechanisms of host cell invasion by Trypanosoma cruzi. Exp. Parasitol. doi:10.1016\/j.exppara.2010.06.023","DOI":"10.1016\/j.exppara.2010.06.023"},{"key":"e_1_3_2_129_2","volume-title":"Emerging Chagas disease","author":"Epting C. L.","year":"2009","unstructured":"Epting C. L. Bonney M. Olson C. L. Engman D. M. . 2009. Cellular host-pathogen relationships, p. 83\u201393.In Teixeira A. R. L. Vinaud M. C. Castro A. M. . (ed.), Emerging Chagas disease, 1st ed. Bentham Science Publishers, New York, NY.","edition":"1"},{"key":"e_1_3_2_130_2","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.445"},{"key":"e_1_3_2_131_2","doi-asserted-by":"publisher","DOI":"10.1080\/0891693042000196200"},{"key":"e_1_3_2_132_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.170.9.4731"},{"key":"e_1_3_2_133_2","doi-asserted-by":"publisher","DOI":"10.1006\/clin.1993.1110"},{"key":"e_1_3_2_134_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81997-2"},{"key":"e_1_3_2_135_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)43250-9"},{"key":"e_1_3_2_136_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000075715"},{"key":"e_1_3_2_137_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2007.04.025"},{"key":"e_1_3_2_138_2","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(91)90118-P"},{"key":"e_1_3_2_139_2","first-page":"449","article-title":"Recent advances in South American mammalian paleontology","volume":"13","author":"Flynn J. J.","year":"1998","unstructured":"Flynn J. J. Wyss A. R. . 1998. Recent advances in South American mammalian paleontology. Tree 13:449\u2013454.","journal-title":"Tree"},{"key":"e_1_3_2_140_2","doi-asserted-by":"publisher","DOI":"10.11646\/zootaxa.670.1.1"},{"key":"e_1_3_2_141_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-282X1980000100006"},{"key":"e_1_3_2_142_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2005.01.024"},{"key":"e_1_3_2_143_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.096305"},{"key":"e_1_3_2_144_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2009.02.010"},{"key":"e_1_3_2_145_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.170.5.2613"},{"key":"e_1_3_2_146_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1461-0248.2007.01133.x"},{"key":"e_1_3_2_147_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.molbev.a004133"},{"key":"e_1_3_2_148_2","first-page":"11","article-title":"Found: two cases of Chagas disease","volume":"9","author":"Geer D. A","year":"1955","unstructured":"Geer D. A . 1955. Found: two cases of Chagas disease. Texas Health Bull. 9:11.","journal-title":"Texas Health Bull."},{"key":"e_1_3_2_149_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbiopara.2003.11.012"},{"key":"e_1_3_2_150_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature08939"},{"key":"e_1_3_2_151_2","doi-asserted-by":"publisher","DOI":"10.1128\/CDLI.8.6.1039-1043.2001"},{"key":"e_1_3_2_152_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI10734"},{"key":"e_1_3_2_153_2","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1381.046"},{"key":"e_1_3_2_154_2","first-page":"89","article-title":"Trypanosoma cruzi-induced molecular mimicry and Chagas' disease","volume":"296","author":"Giron\u00e8s N.","year":"2005","unstructured":"Giron\u00e8s N. Cuervo H. Fresno M. . 2005. Trypanosoma cruzi-induced molecular mimicry and Chagas' disease. Curr. Top. Microbiol. Immunol. 296:89\u2013123.","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"e_1_3_2_155_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmcc.2001.1416"},{"key":"e_1_3_2_156_2","doi-asserted-by":"publisher","DOI":"10.2307\/3275569"},{"key":"e_1_3_2_157_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.12.1709"},{"key":"e_1_3_2_158_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02788040"},{"key":"e_1_3_2_159_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkg798"},{"key":"e_1_3_2_160_2","doi-asserted-by":"publisher","DOI":"10.1186\/ar2758"},{"key":"e_1_3_2_161_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652009000500002"},{"key":"e_1_3_2_162_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetimm.2009.01.004"},{"key":"e_1_3_2_163_2","first-page":"105","article-title":"American trypanosomiasis","volume":"73","author":"Guerra F","year":"1970","unstructured":"Guerra F . 1970. American trypanosomiasis. A historical and a human lesson. J. Trop. Med. Hyg. 73:105\u2013118.","journal-title":"A historical and a human lesson. J. Trop. Med. Hyg."},{"key":"e_1_3_2_164_2","doi-asserted-by":"publisher","DOI":"10.1128\/EC.00113-10"},{"key":"e_1_3_2_165_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000447"},{"key":"e_1_3_2_166_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3024.2009.01108.x"},{"key":"e_1_3_2_167_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1838(00)00076-X"},{"key":"e_1_3_2_168_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ympev.2007.03.023"},{"key":"e_1_3_2_169_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2004.10.002"},{"key":"e_1_3_2_170_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2009.12.009"},{"key":"e_1_3_2_171_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.6812218"},{"key":"e_1_3_2_172_2","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.4049\/jimmunol.127.3.1126","article-title":"Increased natural killer cell activity in experimental American trypanosomiasis","volume":"127","author":"Hatcher F. M.","year":"1981","unstructured":"Hatcher F. M. Kuhn R. E. Cerrone M. C. Burton R. C. . 1981. Increased natural killer cell activity in experimental American trypanosomiasis. J. Immunol. 127:1126\u20131130.","journal-title":"J. Immunol."},{"key":"e_1_3_2_173_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000237"},{"key":"e_1_3_2_174_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009181"},{"key":"e_1_3_2_175_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2006.75.893"},{"key":"e_1_3_2_176_2","first-page":"87","article-title":"Pathogenesis of Chagas disease: lateral DNA transfer, genotype alterations and autoimmunity.","volume":"42","author":"Hecht M. M.","year":"2009","unstructured":"Hecht M. M. Nitz N. Araujo P. F. Teixeira A. R. L. . 2009. Pathogenesis of Chagas disease: lateral DNA transfer, genotype alterations and autoimmunity. Rev. Soc. Bras. Med. Trop. 42(Suppl.):87\u201393.","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"e_1_3_2_177_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkl1137"},{"key":"e_1_3_2_178_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.trstmh.2008.04.041"},{"key":"e_1_3_2_179_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkh007"},{"key":"e_1_3_2_180_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm1061"},{"key":"e_1_3_2_181_2","first-page":"187","article-title":"Serologic surveillance of Chagas disease","volume":"65","author":"Hoff R.","year":"1985","unstructured":"Hoff R. . 1985. Serologic surveillance of Chagas disease. Ann. Soc. Belg. Med. Trop. 65:187\u2013196.","journal-title":"Ann. Soc. Belg. Med. Trop."},{"key":"e_1_3_2_182_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.68.8.5126-5132.1994"},{"key":"e_1_3_2_183_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(73)90088-X"},{"key":"e_1_3_2_184_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2006.01.001"},{"key":"e_1_3_2_185_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00423-07"},{"key":"e_1_3_2_186_2","first-page":"405","article-title":"Clinical, parasitological and histopathologic follow-up studies of acute Chagas patients treated with benznidazole. Arch","volume":"68","author":"Inglessis I.","year":"1998","unstructured":"Inglessis I. . 1998. Clinical, parasitological and histopathologic follow-up studies of acute Chagas patients treated with benznidazole. Arch. Inst. Cardiol. Mex. 68:405\u2013410.","journal-title":"Inst. Cardiol. Mex."},{"key":"e_1_3_2_187_2","doi-asserted-by":"publisher","DOI":"10.1080\/08916930802024574"},{"key":"e_1_3_2_188_2","first-page":"197","article-title":"Plasma membrane ATP receptors in Trypanosoma cruzi trypomastigotes","volume":"5","author":"Inverso J. A.","year":"1995","unstructured":"Inverso J. A. Song Y. Santos-Buch C. A. . 1995. Plasma membrane ATP receptors in Trypanosoma cruzi trypomastigotes. Receptor 5:197\u2013206.","journal-title":"Receptor"},{"key":"e_1_3_2_189_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1112680"},{"key":"e_1_3_2_190_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2005.01.006"},{"key":"e_1_3_2_191_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.35.2.588-593.1982"},{"key":"e_1_3_2_192_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M702023200"},{"key":"e_1_3_2_193_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(87)90154-1"},{"key":"e_1_3_2_194_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1566-0702(02)00014-0"},{"key":"e_1_3_2_195_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.5.1872"},{"key":"e_1_3_2_196_2","first-page":"299","article-title":"Anticancer properties of flagellate protozoan Trypanosoma cruzi Chagas","volume":"3","author":"Kallinikova V. D.","year":"2001","unstructured":"Kallinikova V. D. . 2001. Anticancer properties of flagellate protozoan Trypanosoma cruzi Chagas. Izv. Akad. Nauk. SSSR Biol. 3:299\u2013311.","journal-title":"Izv. Akad. Nauk. SSSR Biol."},{"key":"e_1_3_2_197_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200939289"},{"key":"e_1_3_2_198_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200312170"},{"key":"e_1_3_2_199_2","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(96)20050-X"},{"key":"e_1_3_2_200_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.12.2.210"},{"key":"e_1_3_2_201_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0928-8244(03)00097-X"},{"key":"e_1_3_2_202_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2005.08.013"},{"key":"e_1_3_2_203_2","doi-asserted-by":"publisher","DOI":"10.2307\/3281173"},{"key":"e_1_3_2_204_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.24.1.117-120.1979"},{"key":"e_1_3_2_205_2","doi-asserted-by":"publisher","DOI":"10.2307\/3280439"},{"key":"e_1_3_2_206_2","first-page":"1","article-title":"Mechanisms of natural resistance to trypanosomal infection. Role of complement in avian resistance to Trypanosoma cruzi infection.","volume":"30","author":"Kierszenbaum F.","year":"1976","unstructured":"Kierszenbaum F. Ivanyi J. Budzko D. B. . 1976. Mechanisms of natural resistance to trypanosomal infection. Role of complement in avian resistance to Trypanosoma cruzi infection. Immunology 30:1\u20136.","journal-title":"Immunology"},{"key":"e_1_3_2_207_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biosystems.2009.10.009"},{"key":"e_1_3_2_208_2","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511623486"},{"key":"e_1_3_2_209_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.1.602"},{"key":"e_1_3_2_210_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1981.30.47"},{"key":"e_1_3_2_211_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2009.05.005"},{"key":"e_1_3_2_212_2","volume-title":"Fields virology","author":"Knipe D. M.","year":"2007","unstructured":"Knipe D. M. Howley P. M. . (ed.). 2007. Fields virology, 5th ed. Lippincott Williams & Wilkins, Philadelphia, PA.","edition":"5"},{"key":"e_1_3_2_213_2","first-page":"79","article-title":"Etiologia e patogenia do megaes\u00f4fago no Brasil","volume":"9","author":"Koeberle F","year":"1963","unstructured":"Koeberle F . 1963. Etiologia e patogenia do megaes\u00f4fago no Brasil. Rev. Goiana Med. 9:79\u2013116.","journal-title":"Rev. Goiana Med."},{"key":"e_1_3_2_214_2","first-page":"739","article-title":"The causation and importance of nervous lesions in American trypanosomiasis","volume":"42","author":"Koeberle F","year":"1970","unstructured":"Koeberle F . 1970. The causation and importance of nervous lesions in American trypanosomiasis. Bull. World Health Organ. 42:739\u2013743.","journal-title":"Bull. World Health Organ."},{"key":"e_1_3_2_215_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2009.11.007"},{"key":"e_1_3_2_216_2","doi-asserted-by":"publisher","DOI":"10.1038\/257394a0"},{"key":"e_1_3_2_217_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762009000900020"},{"key":"e_1_3_2_218_2","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(75)90113-7"},{"key":"e_1_3_2_219_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1970.19.932"},{"key":"e_1_3_2_220_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2001.65.435"},{"key":"e_1_3_2_221_2","first-page":"153","article-title":"Immunopathologic and morphologic studies of skeletal muscle in Chagas' disease","volume":"80","author":"Laguens R. P.","year":"1975","unstructured":"Laguens R. P. . 1975. Immunopathologic and morphologic studies of skeletal muscle in Chagas' disease. Am. J. Pathol. 80:153\u2013162.","journal-title":"Am. J. Pathol."},{"key":"e_1_3_2_222_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.13.4779"},{"key":"e_1_3_2_223_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-007-0249-3"},{"key":"e_1_3_2_224_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761949000200011"},{"key":"e_1_3_2_225_2","doi-asserted-by":"publisher","DOI":"10.1086\/648072"},{"key":"e_1_3_2_226_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2000.63.111"},{"key":"e_1_3_2_227_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkp236"},{"key":"e_1_3_2_228_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2006.08.029"},{"key":"e_1_3_2_229_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(01)00163-1"},{"key":"e_1_3_2_230_2","doi-asserted-by":"publisher","DOI":"10.2741\/1023"},{"key":"e_1_3_2_231_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.171.8.4271"},{"key":"e_1_3_2_232_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.9.5643-5649.2001"},{"key":"e_1_3_2_233_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.6.3410-3417.2004"},{"key":"e_1_3_2_234_2","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(96)20051-1"},{"key":"e_1_3_2_235_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2009.04.001"},{"key":"e_1_3_2_236_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.109.195230"},{"key":"e_1_3_2_237_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.173.3.1887"},{"key":"e_1_3_2_238_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1181369"},{"key":"e_1_3_2_239_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-6851(01)00236-5"},{"key":"e_1_3_2_240_2","first-page":"1994","article-title":"Role of interleukin 17 in viral myocarditis and dilated cardiomyopathy","volume":"29","author":"Lin S.","year":"2009","unstructured":"Lin S. Huang Y. L. Wu W. F. Li Y. Tang S. D. . 2009. Role of interleukin 17 in viral myocarditis and dilated cardiomyopathy. Nan Fang Yi Ke Da Xue Xue Bao 29:1994\u20131999.(In Chinese.)","journal-title":"Nan Fang Yi Ke Da Xue Xue Bao"},{"key":"e_1_3_2_241_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2009.07.002"},{"key":"e_1_3_2_242_2","doi-asserted-by":"publisher","DOI":"10.1042\/bj3450693"},{"key":"e_1_3_2_243_2","doi-asserted-by":"publisher","DOI":"10.1016\/0888-7543(95)80010-J"},{"key":"e_1_3_2_244_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(74)90084-8"},{"key":"e_1_3_2_245_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761982000300004"},{"key":"e_1_3_2_246_2","doi-asserted-by":"publisher","DOI":"10.1016\/0020-7519(78)90069-3"},{"key":"e_1_3_2_247_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0713598"},{"key":"e_1_3_2_248_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.65.11.5813-5819.1991"},{"key":"e_1_3_2_249_2","first-page":"561","article-title":"Morphology of Trypanosoma cruzi in cells of chicken and lizards (Tropidurus hispidus, Sauria: Iguanidae) cultured at 37 degrees and 33 degrees C","volume":"33","author":"Lugo-Hern\u00e1ndez A","year":"1973","unstructured":"Lugo-Hern\u00e1ndez A . 1973. Morphology of Trypanosoma cruzi in cells of chicken and lizards (Tropidurus hispidus, Sauria: Iguanidae) cultured at 37 degrees and 33 degrees C. Rev. Bras. Biol. 33:561\u2013573.","journal-title":"Rev. Bras. Biol."},{"key":"e_1_3_2_250_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00294-005-0027-0"},{"key":"e_1_3_2_251_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.4.2589-2595.2001"},{"key":"e_1_3_2_252_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761999000700059"},{"key":"e_1_3_2_253_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(00)80191-4"},{"key":"e_1_3_2_254_2","first-page":"271","article-title":"Hemodynamic study of the intermediate form of Chagas' disease","volume":"38","author":"Mady C.","year":"1982","unstructured":"Mady C. de Moraes A. V. Galiano N. Decourt L. V. . 1982. Hemodynamic study of the intermediate form of Chagas' disease. Arq. Bras. Cardiol. 38:271\u2013275.","journal-title":"Arq. Bras. Cardiol."},{"key":"e_1_3_2_255_2","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.17.10.1427"},{"key":"e_1_3_2_256_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762005000500017"},{"key":"e_1_3_2_257_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00059-005-2730-5"},{"key":"e_1_3_2_258_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.09.028"},{"key":"e_1_3_2_259_2","first-page":"430","article-title":"Editing machines: the complexities of trypanosome RNA editing","volume":"108","author":"Mandison-Antenucci S.","year":"2002","unstructured":"Mandison-Antenucci S. Grams J. Hajduk S. L. . 2002. Editing machines: the complexities of trypanosome RNA editing. Cell 108:430\u2013438.","journal-title":"Cell"},{"key":"e_1_3_2_260_2","doi-asserted-by":"publisher","DOI":"10.1128\/EC.4.6.1137-1146.2005"},{"key":"e_1_3_2_261_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2009.07.003"},{"key":"e_1_3_2_262_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2005.10.007"},{"key":"e_1_3_2_263_2","volume-title":"Acquiring genomes. A theory of the origin of species.","author":"Margulis L.","year":"2002","unstructured":"Margulis L. Sagan D. . 2002. Acquiring genomes. A theory of the origin of species. Basic Books, New York, NY."},{"key":"e_1_3_2_264_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2007.12.013"},{"key":"e_1_3_2_265_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.624296"},{"key":"e_1_3_2_266_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762005000900015"},{"key":"e_1_3_2_267_2","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(68)90010-2"},{"key":"e_1_3_2_268_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00275-10"},{"key":"e_1_3_2_269_2","doi-asserted-by":"publisher","DOI":"10.1155\/JBB\/2006\/45621"},{"key":"e_1_3_2_270_2","doi-asserted-by":"publisher","DOI":"10.1128\/EC.3.2.506-517.2004"},{"key":"e_1_3_2_271_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(03)00143-6"},{"key":"e_1_3_2_272_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199703063361010"},{"key":"e_1_3_2_273_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1722352"},{"key":"e_1_3_2_274_2","doi-asserted-by":"publisher","DOI":"10.1155\/2009\/374696"},{"key":"e_1_3_2_275_2","first-page":"815","article-title":"Cas de trypanosomose humaine observe dans la ville de Jujuy","volume":"95","author":"Mazza S","year":"1995","unstructured":"Mazza S . 1995. Cas de trypanosomose humaine observe dans la ville de Jujuy. Compt. Rend. Soc. Biol. 95:815.","journal-title":"Compt. Rend. Soc. Biol."},{"key":"e_1_3_2_276_2","first-page":"809","article-title":"Infeccion spontann\u00e9e du chien par le Schizotrypanum cruzi","volume":"270","author":"Mazza S","year":"1995","unstructured":"Mazza S . 1995. Infeccion spontann\u00e9e du chien par le Schizotrypanum cruzi . Compt. Rend. Soc. Biol. 270:809\u2013811.","journal-title":"Compt. Rend. Soc. Biol."},{"key":"e_1_3_2_277_2","first-page":"296","article-title":"Exposition of contributions of M.E.P. R. A. to the knowledge of biopathology of Chagas' disease.","volume":"58","author":"Mazza S","year":"1951","unstructured":"Mazza S . 1951. Exposition of contributions of M.E.P. R. A. to the knowledge of biopathology of Chagas' disease. Sem. Med. 58:296\u2013300.","journal-title":"Sem. Med."},{"key":"e_1_3_2_278_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2008.08.007"},{"key":"e_1_3_2_279_2","first-page":"107","article-title":"Evaluation of blood tests, complement-mediated lysis and polymerase chain reaction in the verification of therapeutic efficacy in Chagas disease","volume":"39","author":"Meira W. S.","year":"2006","unstructured":"Meira W. S. . 2006. Evaluation of blood tests, complement-mediated lysis and polymerase chain reaction in the verification of therapeutic efficacy in Chagas disease. Rev. Soc. Bras. Med. Trop. 39(Suppl. 3):107\u2013109.","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"e_1_3_2_280_2","first-page":"629","article-title":"Exposure to mixed asymptomatic infections with Trypanosoma cruzi, Leishmania braziliensis and Leishmania chagasi in the human population of the greater Amazon. Trop. Med","volume":"12","author":"Mendes D. G.","year":"2007","unstructured":"Mendes D. G. . 2007. Exposure to mixed asymptomatic infections with Trypanosoma cruzi, Leishmania braziliensis and Leishmania chagasi in the human population of the greater Amazon. Trop. Med. Int. Health 12:629\u2013636.","journal-title":"Int. Health"},{"key":"e_1_3_2_281_2","first-page":"127","article-title":"Basal motility of dilated and non-dilated sigmoid colon and rectum in Chagas' disease","volume":"19","author":"Meneghelli U. G.","year":"1982","unstructured":"Meneghelli U. G. . 1982. Basal motility of dilated and non-dilated sigmoid colon and rectum in Chagas' disease. Arq. Gastroenterol. 19:127\u2013132.","journal-title":"Arq. Gastroenterol."},{"key":"e_1_3_2_282_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000021028"},{"key":"e_1_3_2_283_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00560-09"},{"key":"e_1_3_2_284_2","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(81)90090-0"},{"key":"e_1_3_2_285_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762009000900005"},{"key":"e_1_3_2_286_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2010.01.001"},{"key":"e_1_3_2_287_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrfmmm.2009.02.011"},{"key":"e_1_3_2_288_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.167.8.4574"},{"key":"e_1_3_2_289_2","first-page":"1324","article-title":"Patterns of cytokines and soluble cellular receptors in the sera of children with acute Chagas' disease","volume":"9","author":"Moretti E.","year":"2002","unstructured":"Moretti E. Basso B. Cervetta L. Brigada A. Barbieri G. . 2002. Patterns of cytokines and soluble cellular receptors in the sera of children with acute Chagas' disease. Clin. Diagn. Lab. Immunol. 9:1324\u20131327.","journal-title":"Clin. Diagn. Lab. Immunol."},{"key":"e_1_3_2_290_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature05560"},{"key":"e_1_3_2_291_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.27.7.1477-1482.1989"},{"key":"e_1_3_2_292_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20090900"},{"key":"e_1_3_2_293_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2249.2002.01815.x"},{"key":"e_1_3_2_294_2","first-page":"131","article-title":"Refractoriness of hens towards Trypanosoma (Schizotrypanum) cruzi. III. Dissociation of phenomena of the refractory state and lysis of the epimastigotes by fowl serum. Mem","volume":"72","author":"Nery-Guimar\u00e3es F.","year":"1974","unstructured":"Nery-Guimar\u00e3es F. Ven\u00e2ncio I. Grynberg N. . 1974. Refractoriness of hens towards Trypanosoma (Schizotrypanum) cruzi. III. Dissociation of phenomena of the refractory state and lysis of the epimastigotes by fowl serum. Mem. Inst. Oswaldo Cruz 72:131\u2013136.","journal-title":"Inst. Oswaldo Cruz"},{"key":"e_1_3_2_295_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2004.12.004"},{"key":"e_1_3_2_296_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2004.07.001"},{"key":"e_1_3_2_297_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.10.005"},{"key":"e_1_3_2_298_2","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2007-8-3-r37"},{"key":"e_1_3_2_299_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2009.11.009"},{"key":"e_1_3_2_300_2","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e02-08-0525"},{"key":"e_1_3_2_301_2","first-page":"1092","article-title":"A natural human model of intrinsic heart nervous system denervation: Chagas' cardiopathy","volume":"110","author":"Oliveira J. S","year":"1985","unstructured":"Oliveira J. S . 1985. A natural human model of intrinsic heart nervous system denervation: Chagas' cardiopathy. Hum. Pathol. 110:1092\u20131098.","journal-title":"Hum. Pathol."},{"key":"e_1_3_2_302_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.shpsc.2004.12.002"},{"key":"e_1_3_2_303_2","doi-asserted-by":"publisher","DOI":"10.1021\/pr034075o"},{"key":"e_1_3_2_304_2","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.200300637"},{"key":"e_1_3_2_305_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2009.07.006"},{"key":"e_1_3_2_306_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200636705"},{"key":"e_1_3_2_307_2","volume-title":"Scientific publication 547.","author":"Pan-American Health Organization.","year":"1994","unstructured":"Pan-American Health Organization. 1994. Chagas disease and the nervous system. Scientific publication 547. Pan-American Health Organization, Washington, DC."},{"key":"e_1_3_2_308_2","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.65.1.16-22.1991"},{"key":"e_1_3_2_309_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5273(97)02952-5"},{"key":"e_1_3_2_310_2","doi-asserted-by":"publisher","DOI":"10.1002\/jms.1267"},{"key":"e_1_3_2_311_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0901843"},{"key":"e_1_3_2_312_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.66.2.404"},{"key":"e_1_3_2_313_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejheart.2004.07.002"},{"key":"e_1_3_2_314_2","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxm107"},{"key":"e_1_3_2_315_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762009000900016"},{"key":"e_1_3_2_316_2","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-72.2.441"},{"key":"e_1_3_2_317_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0037-86822003000400005"},{"key":"e_1_3_2_318_2","first-page":"2379","article-title":"IL-17 and IL-22 are associated with protection against human kala azar caused by Leishmania donovani. J. Clin","volume":"119","author":"Pitta M. G.","year":"2009","unstructured":"Pitta M. G. . 2009. IL-17 and IL-22 are associated with protection against human kala azar caused by Leishmania donovani. J. Clin. Invest. 119:2379\u20132387.","journal-title":"Invest."},{"key":"e_1_3_2_319_2","doi-asserted-by":"publisher","DOI":"10.1089\/vbz.2005.5.72"},{"key":"e_1_3_2_320_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(20)30574-2"},{"key":"e_1_3_2_321_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(01)00065-2"},{"key":"e_1_3_2_322_2","first-page":"209","article-title":"Hematophagous insects as vectors for frog trypanosomes","volume":"25","author":"Ramos B.","year":"1977","unstructured":"Ramos B. Urdaneta-Morales S. . 1977. Hematophagous insects as vectors for frog trypanosomes. Rev. Biol. Trop. 25:209\u2013217.","journal-title":"Rev. Biol. Trop."},{"key":"e_1_3_2_323_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5273(95)02482-4"},{"key":"e_1_3_2_324_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0066-782X2001000100008"},{"key":"e_1_3_2_325_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.28.2.404-410.1980"},{"key":"e_1_3_2_326_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762003000900025"},{"key":"e_1_3_2_327_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2008.10.034"},{"key":"e_1_3_2_328_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762002000700016"},{"key":"e_1_3_2_329_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi00630a013"},{"key":"e_1_3_2_330_2","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(74)90044-3"},{"key":"e_1_3_2_331_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00328752"},{"key":"e_1_3_2_332_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0037-86821987000400006"},{"key":"e_1_3_2_333_2","volume-title":"Emerging Chagas disease","author":"Rodrigues M. M.","year":"2009","unstructured":"Rodrigues M. M. Alencar B. C. Vasconcelos J. R. . 2009. Acquired immunity against Trypanosoma cruzi infection and vaccine development, p. 94\u2013103.In Teixeira A. R. L. Vinaud M. C. Castro A. M. . (ed.), Emerging Chagas disease, 1st ed. Bentham Science Publishers, New York, NY.","edition":"1"},{"key":"e_1_3_2_334_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.31.2.524-529.1981"},{"key":"e_1_3_2_335_2","doi-asserted-by":"publisher","DOI":"10.1006\/clin.1993.1102"},{"key":"e_1_3_2_336_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(90)90191-Y"},{"key":"e_1_3_2_337_2","first-page":"820","article-title":"Connective tissue skeleton in the normal left ventricle and in hypertensive left ventricular hypertrophy and chronic chagasic myocarditis","volume":"7","author":"Rossi M. A","year":"2001","unstructured":"Rossi M. A . 2001. Connective tissue skeleton in the normal left ventricle and in hypertensive left ventricular hypertrophy and chronic chagasic myocarditis. Med. Sci. Monit. 7:820\u2013832.","journal-title":"Med. Sci. Monit."},{"key":"e_1_3_2_338_2","doi-asserted-by":"publisher","DOI":"10.2144\/99276st03"},{"key":"e_1_3_2_339_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2009.12.019"},{"key":"e_1_3_2_340_2","doi-asserted-by":"publisher","DOI":"10.1093\/jmedent\/2.1.87"},{"key":"e_1_3_2_341_2","first-page":"29","article-title":"A novel receptor mediated ATP transport system regulated by tyrosine and serine\/threonine phosphokinases in Trypanosoma cruzi trypomastigotes","volume":"7","author":"Sadigursky M.","year":"1997","unstructured":"Sadigursky M. Santos-Buch C. A. . 1997. A novel receptor mediated ATP transport system regulated by tyrosine and serine\/threonine phosphokinases in Trypanosoma cruzi trypomastigotes. Recept. Signal Transduct. 7:29\u201343.","journal-title":"Recept. Signal Transduct."},{"key":"e_1_3_2_342_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761988000500024"},{"key":"e_1_3_2_343_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2008.03.008"},{"key":"e_1_3_2_344_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3024.1999.00242.x"},{"key":"e_1_3_2_345_2","doi-asserted-by":"publisher","DOI":"10.1038\/268340a0"},{"key":"e_1_3_2_346_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.37.1.275"},{"key":"e_1_3_2_347_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.140.1.38"},{"key":"e_1_3_2_348_2","doi-asserted-by":"publisher","DOI":"10.1515\/BC.2008.126"},{"key":"e_1_3_2_349_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-78267-6_11"},{"key":"e_1_3_2_350_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762009000900025"},{"key":"e_1_3_2_351_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.192.9.1289"},{"key":"e_1_3_2_352_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652001000400011"},{"key":"e_1_3_2_353_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1984.03340460061025"},{"key":"e_1_3_2_354_2","first-page":"1021","article-title":"Expression pattern and cellular origin of cytokines in the normal and Toxoplasma gondii-infected murine brain","volume":"150","author":"Schl\u00fcter D.","year":"1997","unstructured":"Schl\u00fcter D. Kaefer N. Hof H. Wiestler O. D. Deckert-Schl\u00fcter M. . 1997. Expression pattern and cellular origin of cytokines in the normal and Toxoplasma gondii-infected murine brain. Am. J. Pathol. 150:1021\u20131035.","journal-title":"Am. J. Pathol."},{"key":"e_1_3_2_355_2","doi-asserted-by":"publisher","DOI":"10.1002\/1096-9071(200008)61:4<518::AID-JMV16>3.0.CO;2-F"},{"key":"e_1_3_2_356_2","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.1108693"},{"key":"e_1_3_2_357_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2009.11.003"},{"key":"e_1_3_2_358_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.12.040194.003223"},{"key":"e_1_3_2_359_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9896(199709)183:1<105::AID-PATH1094>3.0.CO;2-E"},{"key":"e_1_3_2_360_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm317"},{"key":"e_1_3_2_361_2","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0709517"},{"key":"e_1_3_2_362_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2003.12.005"},{"key":"e_1_3_2_363_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.mi.49.100195.001001"},{"key":"e_1_3_2_364_2","first-page":"412","article-title":"Immunobiology of leishmaniasis","volume":"47","author":"Sharma U.","year":"2009","unstructured":"Sharma U. Singh S. . 2009. Immunobiology of leishmaniasis. Indian J. Exp. Biol. 47:412\u2013423.","journal-title":"Indian J. Exp. Biol."},{"key":"e_1_3_2_365_2","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2007.111"},{"key":"e_1_3_2_366_2","first-page":"156","article-title":"Peripheral nervous system involvement in human and experimental chronic American trypanosomiasis","volume":"88","author":"Sica R. E.","year":"1995","unstructured":"Sica R. E. Gonzalez Cappa S. M. Sanz O. P. Mirkin G. . 1995. Peripheral nervous system involvement in human and experimental chronic American trypanosomiasis. Bull. Soc. Pathol. Exot. 88:156\u2013163.","journal-title":"Bull. Soc. Pathol. Exot."},{"key":"e_1_3_2_367_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2009.00524.x"},{"key":"e_1_3_2_368_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0037-86822000000200006"},{"key":"e_1_3_2_369_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762006000800003"},{"key":"e_1_3_2_370_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2006.02.006"},{"key":"e_1_3_2_371_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ympev.2007.11.035"},{"key":"e_1_3_2_372_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(89)80784-7"},{"key":"e_1_3_2_373_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00203-008-0439-6"},{"key":"e_1_3_2_374_2","first-page":"65","article-title":"Mitosis and genome partition in trypanosomes","volume":"19","author":"Solari A. J","year":"1995","unstructured":"Solari A. J . 1995. Mitosis and genome partition in trypanosomes. Biocell 19:65\u201384.","journal-title":"Biocell"},{"key":"e_1_3_2_375_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2006.09.033"},{"key":"e_1_3_2_376_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1998.59.526"},{"key":"e_1_3_2_377_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01931-06"},{"key":"e_1_3_2_378_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2004.02.011"},{"key":"e_1_3_2_379_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygeno.2008.09.016"},{"key":"e_1_3_2_380_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2009.05.014"},{"key":"e_1_3_2_381_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(58)90117-4"},{"key":"e_1_3_2_382_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X1999000400002"},{"key":"e_1_3_2_383_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-308X(01)48003-1"},{"key":"e_1_3_2_384_2","doi-asserted-by":"crossref","first-page":"871","DOI":"10.3201\/eid1605.091440","article-title":"Physician awareness of Chagas disease, USA. Emerg","volume":"16","author":"Stimpert K. K.","year":"2010","unstructured":"Stimpert K. K. Montgomery S. P. . 2010. Physician awareness of Chagas disease, USA. Emerg. Infect. Dis. 16:871\u2013872.","journal-title":"Infect. Dis."},{"key":"e_1_3_2_385_2","volume-title":"Emerging Chagas disease","author":"Sturm N. R","year":"2009","unstructured":"Sturm N. R . 2009. Trypanosoma cruzi mitochondrial DNA and the parasite lifecycle, p. 63\u201369.In Teixeira A. R. L. Vinaud M. C. Castro A. M. . (ed.), Emerging Chagas disease, 1st ed. Bentham Science Publishers, New York, NY.","edition":"1"},{"key":"e_1_3_2_386_2","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(89)90082-0"},{"key":"e_1_3_2_387_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000461"},{"key":"e_1_3_2_388_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.164.10.5375"},{"key":"e_1_3_2_389_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1970.19.405"},{"key":"e_1_3_2_390_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00548079"},{"key":"e_1_3_2_391_2","first-page":"347","article-title":"Electron microscopy of the myocardium in human trypanosomiasis cruzi.","volume":"15","author":"Tafuri W. L.","year":"1973","unstructured":"Tafuri W. L. Maria T. A. Lopes E. R. Chapadeiro E. . 1973. Electron microscopy of the myocardium in human trypanosomiasis cruzi. Rev. Inst. Med. Trop. Sao Paulo 15:347\u2013370.","journal-title":"Rev. Inst. Med. Trop. Sao Paulo"},{"key":"e_1_3_2_392_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(81)90069-2"},{"key":"e_1_3_2_393_2","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(89)90102-3"},{"key":"e_1_3_2_394_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2009.02.001"},{"key":"e_1_3_2_395_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.5.4.400"},{"key":"e_1_3_2_396_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(01)00158-8"},{"key":"e_1_3_2_397_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2003.08.008"},{"key":"e_1_3_2_398_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-4758(99)01398-8"},{"key":"e_1_3_2_399_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.8.3932"},{"key":"e_1_3_2_400_2","first-page":"363","article-title":"Chagas' disease in inbred III\/J rabbits","volume":"124","author":"Teixeira A. R","year":"1986","unstructured":"Teixeira A. R . 1986. Chagas' disease in inbred III\/J rabbits. Am. J. Pathol. 124:363\u2013365.","journal-title":"Am. J. Pathol."},{"key":"e_1_3_2_401_2","volume-title":"Microorganisms and autoimmune diseases","author":"Teixeira A. R. L.","year":"1996","unstructured":"Teixeira A. R. L. Ripoll C. M. Santos-Buch C. A. . 1996. Autoimmunity in Chagas disease, p. 233\u2013255.In Friedman H. Rose N. R. Bendinelli M. . (ed.), Microorganisms and autoimmune diseases. Plenum Press, New York, NY."},{"key":"e_1_3_2_402_2","volume-title":"Immunity to blood parasites of animals and man","author":"Teixeira A. R. L","year":"1987","unstructured":"Teixeira A. R. L . 1987. Immunoprophylaxis against Chagas disease, p. 243\u2013280.In Miller L. H. Pino J. A McKelvey J. J. Jr. . (ed.), Immunity to blood parasites of animals and man. Plenum Press, New York, NY."},{"key":"e_1_3_2_403_2","first-page":"859","article-title":"The immunology of experimental Chagas' disease. I. Preparation of Trypanosoma cruzi antigens and humoral antibody response to these antigens.","volume":"113","author":"Teixeira A. R. L.","year":"1974","unstructured":"Teixeira A. R. L. Santos-Buch C. A. . 1974. The immunology of experimental Chagas' disease. I. Preparation of Trypanosoma cruzi antigens and humoral antibody response to these antigens. J. Immunol. 113:859\u2013869.","journal-title":"J. Immunol."},{"key":"e_1_3_2_404_2","first-page":"401","article-title":"The immunology of experimental Chagas' disease. II. Delayed hypersensitivity to Trypanosoma cruzi antigens.","volume":"28","author":"Teixeira A. R. L.","year":"1975","unstructured":"Teixeira A. R. L. Santos-Buch C. A. . 1975. The immunology of experimental Chagas' disease. II. Delayed hypersensitivity to Trypanosoma cruzi antigens. Immunology 28:401\u2013410.","journal-title":"Immunology"},{"key":"e_1_3_2_405_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001000"},{"key":"e_1_3_2_406_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0037-86821983000100003"},{"key":"e_1_3_2_407_2","doi-asserted-by":"crossref","DOI":"10.2174\/97816080504131090101","volume-title":"Emerging Chagas disease","author":"Teixeira A. R. L.","year":"2009","unstructured":"Teixeira A. R. L. Pimentel F. Cordeiro C. . 2009. The pathology of Chagas disease, p. 110\u2013121.In Teixeira A. R. L. Vinaud M. C. Castro A. M. . (ed.), Emerging Chagas disease, 1st ed. Bentham Science Publishers, New York, NY.","edition":"1"},{"key":"e_1_3_2_408_2","first-page":"176","article-title":"Acute Chagas disease","volume":"3","author":"Teixeira A. R. L.","year":"1970","unstructured":"Teixeira A. R. L. Roters F. Mott K. E. . 1970. Acute Chagas disease. Gaz. Med. Bahia 3:176\u2013186.","journal-title":"Gaz. Med. Bahia"},{"key":"e_1_3_2_409_2","doi-asserted-by":"crossref","DOI":"10.2174\/97816080504131090101","volume-title":"Emerging Chagas disease","author":"Teixeira A. R. L.","year":"2009","unstructured":"Teixeira A. R. L. Vinaud M. C. Castro A. M. . 2009. Chagas disease: a global health problem, p. 18\u201323.In Teixeira A. R. L. Vinaud M. C. Castro A. M. . (ed.), Emerging Chagas disease, 1st ed. Bentham Science Publishers, New York, NY.","edition":"1"},{"key":"e_1_3_2_410_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2006.047357"},{"key":"e_1_3_2_411_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762006000500001"},{"key":"e_1_3_2_412_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0037-86821995000300016"},{"key":"e_1_3_2_413_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2009001300004"},{"key":"e_1_3_2_414_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/162.6.1420"},{"key":"e_1_3_2_415_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0037-86821991000100010"},{"key":"e_1_3_2_416_2","doi-asserted-by":"publisher","DOI":"10.1016\/0027-5107(94)90240-2"},{"key":"e_1_3_2_417_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI109232"},{"key":"e_1_3_2_418_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1990.43.146"},{"key":"e_1_3_2_419_2","first-page":"77","article-title":"Experimental Chagas' disease in isogenic III\/J rabbits. I. Physiopathology of arrhythmia and sudden death in Chagas' disease patients.","volume":"29","author":"Teixeira A. R.","year":"1983","unstructured":"Teixeira A. R. Junqueira L. F. Jr. Solorzano E. Zappala M. . 1983. Experimental Chagas' disease in isogenic III\/J rabbits. I. Physiopathology of arrhythmia and sudden death in Chagas' disease patients. Rev. Assoc. Med. Bras. 29:77\u201383.","journal-title":"Rev. Assoc. Med. Bras."},{"key":"e_1_3_2_420_2","first-page":"163","article-title":"The immunology of experimental Chagas' disease. IV. Production of lesions in rabbits similar to those of chronic Chagas' disease in man.","volume":"80","author":"Teixeira A. R.","year":"1975","unstructured":"Teixeira A. R. Teixeira M. L. Santos-Buch C. A. . 1975. The immunology of experimental Chagas' disease. IV. Production of lesions in rabbits similar to those of chronic Chagas' disease in man. Am. J. Pathol. 80:163\u2013180.","journal-title":"Am. J. Pathol."},{"key":"e_1_3_2_421_2","doi-asserted-by":"crossref","first-page":"100","DOI":"10.3201\/eid0701.700100","article-title":"Emerging Chagas disease: trophic network and cycle of transmission of Trypanosoma cruzi from palm trees in the Amazon. Emerg","volume":"7","author":"Teixeira A. R.","year":"2001","unstructured":"Teixeira A. R. . 2001. Emerging Chagas disease: trophic network and cycle of transmission of Trypanosoma cruzi from palm trees in the Amazon. Emerg. Infect. Dis. 7:100\u2013112.","journal-title":"Infect. Dis."},{"key":"e_1_3_2_422_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9975(08)80133-8"},{"key":"e_1_3_2_423_2","doi-asserted-by":"publisher","DOI":"10.1515\/BC.1999.066"},{"key":"e_1_3_2_424_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0477fje"},{"key":"e_1_3_2_425_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000065264"},{"key":"e_1_3_2_426_2","first-page":"902","article-title":"Patogenia de la miocarditis cronica em la enfermedad de Chagas","volume":"2","author":"Torres C. M","year":"1930","unstructured":"Torres C. M . 1930. Patogenia de la miocarditis cronica em la enfermedad de Chagas. Soc. Argent. Patol. Reg. Norte Quinta Reun. 2:902.","journal-title":"Soc. Argent. Patol. Reg. Norte Quinta Reun."},{"key":"e_1_3_2_427_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761960000200004"},{"key":"e_1_3_2_428_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-004-1107-7"},{"key":"e_1_3_2_429_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(78)90055-3"},{"key":"e_1_3_2_430_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4894(86)90023-8"},{"key":"e_1_3_2_431_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.180.3.1737"},{"key":"e_1_3_2_432_2","first-page":"99","article-title":"Experimental infections in Venezuelan lizards by Trypanosoma cruzi","volume":"38","author":"Urdaneta-Morales S.","year":"1981","unstructured":"Urdaneta-Morales S. McLure I. . 1981. Experimental infections in Venezuelan lizards by Trypanosoma cruzi . Acta Trop. 38:99\u2013105.","journal-title":"Acta Trop."},{"key":"e_1_3_2_433_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65052-3"},{"key":"e_1_3_2_434_2","first-page":"2153","article-title":"Kinetoplast DNA signatures of Trypanosoma cruzi strains obtained directly from infected tissues","volume":"149","author":"Vago A. R.","year":"1996","unstructured":"Vago A. R. . 1996. Kinetoplast DNA signatures of Trypanosoma cruzi strains obtained directly from infected tissues. Am. J. Pathol. 149:2153\u20132159.","journal-title":"Am. J. Pathol."},{"key":"e_1_3_2_435_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(03)90155-6"},{"key":"e_1_3_2_436_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-9292-3-2"},{"key":"e_1_3_2_437_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2007.00065.x"},{"key":"e_1_3_2_438_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-1229(95)90144-2"},{"key":"e_1_3_2_439_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02761911000200004"},{"key":"e_1_3_2_440_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.5.1.163"},{"key":"e_1_3_2_441_2","volume-title":"Biology of the Kinetoplastida","author":"Vickerman K","year":"1976","unstructured":"Vickerman K . 1976. The diversity of the kinetoplastid flagellates, p. 1\u201334.In Lumsden W. H. R. Evans D. A. . (ed.), Biology of the Kinetoplastida. Academic Press, London, United Kingdom."},{"key":"e_1_3_2_442_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-009-1383-3"},{"key":"e_1_3_2_443_2","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1998.9127"},{"key":"e_1_3_2_444_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1550-7408.2004.tb00387.x"},{"key":"e_1_3_2_445_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1550-7408.1995.tb01535.x"},{"key":"e_1_3_2_446_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200424993"},{"key":"e_1_3_2_447_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ympev.2009.10.014"},{"key":"e_1_3_2_448_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2004.09.003"},{"key":"e_1_3_2_449_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-10-255"},{"key":"e_1_3_2_450_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.25.022106.141557"},{"key":"e_1_3_2_451_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/12.suppl_D.154"},{"key":"e_1_3_2_452_2","unstructured":"Reference deleted."},{"key":"e_1_3_2_453_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0684.2008.00308.x"},{"key":"e_1_3_2_454_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0903416"},{"key":"e_1_3_2_455_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(61)80193-5"},{"key":"e_1_3_2_456_2","first-page":"1","article-title":"Control of Chagas' disease: second report of a WHO Expert Committee. World Health Organ.","volume":"905","author":"World Health Organization.","year":"2002","unstructured":"World Health Organization. 2002. Control of Chagas' disease: second report of a WHO Expert Committee. World Health Organ. Tech. Rep. Ser. 905:1\u2013109.","journal-title":"Tech. Rep. Ser."},{"key":"e_1_3_2_457_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2007.01.003"},{"key":"e_1_3_2_458_2","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.015578-0"},{"key":"e_1_3_2_459_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2004.10.024"},{"key":"e_1_3_2_460_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1999.tb01355.x"},{"key":"e_1_3_2_461_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature07955"},{"key":"e_1_3_2_462_2","doi-asserted-by":"publisher","DOI":"10.1080\/09687860600601494"},{"key":"e_1_3_2_463_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830260116"},{"key":"e_1_3_2_464_2","doi-asserted-by":"publisher","DOI":"10.1086\/314889"},{"key":"e_1_3_2_465_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20091975"},{"key":"e_1_3_2_466_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2009.05.001"},{"key":"e_1_3_2_467_2","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2009.138"},{"key":"e_1_3_2_468_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0897.2002.01097.x"},{"key":"e_1_3_2_469_2","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M700490-MCP200"},{"key":"e_1_3_2_470_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.3421505"}],"container-title":["Clinical Microbiology Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/CMR.00063-10","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/CMR.00063-10","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T18:59:07Z","timestamp":1741287547000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/CMR.00063-10"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":469,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["10.1128\/CMR.00063-10"],"URL":"https:\/\/doi.org\/10.1128\/cmr.00063-10","relation":{},"ISSN":["0893-8512","1098-6618"],"issn-type":[{"value":"0893-8512","type":"print"},{"value":"1098-6618","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,7]]},"assertion":[{"value":"2011-07-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}