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BV is characterized by a shift in the vaginal flora from the dominant\n            <jats:named-content content-type=\"genus-species\">Lactobacillus<\/jats:named-content>\n            to a polymicrobial flora. BV has been associated with a wide array of health issues, including preterm births, pelvic inflammatory disease, increased susceptibility to HIV infection, and other chronic health problems. A number of potential microbial pathogens, singly and in combinations, have been implicated in the disease process. The list of possible agents continues to expand and includes members of a number of genera, including\n            <jats:named-content content-type=\"genus-species\">Gardnerella<\/jats:named-content>\n            ,\n            <jats:named-content content-type=\"genus-species\">Atopobium<\/jats:named-content>\n            ,\n            <jats:named-content content-type=\"genus-species\">Prevotella<\/jats:named-content>\n            ,\n            <jats:named-content content-type=\"genus-species\">Peptostreptococcus<\/jats:named-content>\n            ,\n            <jats:named-content content-type=\"genus-species\">Mobiluncus<\/jats:named-content>\n            ,\n            <jats:named-content content-type=\"genus-species\">Sneathia<\/jats:named-content>\n            ,\n            <jats:named-content content-type=\"genus-species\">Leptotrichia<\/jats:named-content>\n            ,\n            <jats:named-content content-type=\"genus-species\">Mycoplasma<\/jats:named-content>\n            , and BV-associated bacterium 1 (BVAB1) to BVAB3. Efforts to characterize BV using epidemiological, microscopic, microbiological culture, and sequenced-based methods have all failed to reveal an etiology that can be consistently documented in all women with BV. A careful analysis of the available data suggests that what we term BV is, in fact, a set of common clinical signs and symptoms that can be provoked by a plethora of bacterial species with proinflammatory characteristics, coupled to an immune response driven by variability in host immune function.\n          <\/jats:p>","DOI":"10.1128\/cmr.00075-15","type":"journal-article","created":{"date-parts":[[2016,2,11]],"date-time":"2016-02-11T03:43:57Z","timestamp":1455162237000},"page":"223-238","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":577,"title":["The Human Microbiome during Bacterial Vaginosis"],"prefix":"10.1128","volume":"29","author":[{"given":"Andrew B.","family":"Onderdonk","sequence":"first","affiliation":[{"name":"Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA"},{"name":"Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary L.","family":"Delaney","sequence":"additional","affiliation":[{"name":"Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA"},{"name":"Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raina N.","family":"Fichorova","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Boston, Massachusetts, USA"},{"name":"Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61856-X"},{"key":"e_1_3_1_3_2","doi-asserted-by":"crossref","unstructured":"Behrman RE Butler AS\n. 2007. 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