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Management of\n                    <jats:italic>Trypanosoma cruzi<\/jats:italic>\n                    infection in immunocompromised hosts is challenging, particularly because, regardless of antitrypanosomal treatment status, immunocompromised patients with Chagas disease are at risk for\n                    <jats:italic>T. cruzi<\/jats:italic>\n                    reactivation, which can be lethal. Evidence-based practices to prevent and manage\n                    <jats:italic>T. cruzi<\/jats:italic>\n                    reactivation vary depending on the type of immunocompromise. Here, we review available data describing Chagas disease epidemiology, testing, and management practices for various populations of immunocompromised individuals, including people with HIV and patients undergoing solid organ and hematopoietic stem cell transplantation.\n                  <\/jats:p>","DOI":"10.1128\/cmr.00099-23","type":"journal-article","created":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T09:00:28Z","timestamp":1711616428000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":25,"title":["Chagas disease in immunocompromised patients"],"prefix":"10.1128","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0350-8753","authenticated-orcid":true,"given":"Eva H.","family":"Clark","sequence":"first","affiliation":[{"name":"Section of Infectious Diseases, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA"},{"name":"Division of Tropical Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3107-6214","authenticated-orcid":true,"given":"Louisa A.","family":"Messenger","sequence":"additional","affiliation":[{"name":"Department of Environmental and Occupational Health, University of Nevada Las Vegas, Las Vegas, Nevada, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3502-5799","authenticated-orcid":true,"given":"Jeffrey D.","family":"Whitman","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, University of California San Francisco School of Medicine, San Francisco, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8195-7303","authenticated-orcid":false,"given":"Caryn","family":"Bern","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, University of California San Francisco School of Medicine, San Francisco, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","first-page":"33","article-title":"Chagas disease in Latin America: an epidemiological update based on 2010 estimates","volume":"90","author":"Anonymous","year":"2015","unstructured":"Anonymous. 2015. 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