{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T00:29:58Z","timestamp":1793320198269,"version":"4.5.0"},"reference-count":606,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Microbiol Rev"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>\n                    <jats:named-content content-type=\"genus-species\">Streptococcus pyogenes<\/jats:named-content>\n                    , also known as group A\n                    <jats:named-content content-type=\"genus-species\">Streptococcus<\/jats:named-content>\n                    (GAS), causes mild human infections such as pharyngitis and impetigo and serious infections such as necrotizing fasciitis and streptococcal toxic shock syndrome. Furthermore, repeated GAS infections may trigger autoimmune diseases, including acute poststreptococcal glomerulonephritis, acute rheumatic fever, and rheumatic heart disease. Combined, these diseases account for over half a million deaths per year globally. Genomic and molecular analyses have now characterized a large number of GAS virulence determinants, many of which exhibit overlap and redundancy in the processes of adhesion and colonization, innate immune resistance, and the capacity to facilitate tissue barrier degradation and spread within the human host. This improved understanding of the contribution of individual virulence determinants to the disease process has led to the formulation of models of GAS disease progression, which may lead to better treatment and intervention strategies. While GAS remains sensitive to all penicillins and cephalosporins, rising resistance to other antibiotics used in disease treatment is an increasing worldwide concern. Several GAS vaccine formulations that elicit protective immunity in animal models have shown promise in nonhuman primate and early-stage human trials. The development of a safe and efficacious commercial human vaccine for the prophylaxis of GAS disease remains a high priority.\n                  <\/jats:p>","DOI":"10.1128\/cmr.00101-13","type":"journal-article","created":{"date-parts":[[2014,4,2]],"date-time":"2014-04-02T13:05:34Z","timestamp":1396443934000},"page":"264-301","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":848,"title":["Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus"],"prefix":"10.1128","volume":"27","author":[{"given":"Mark J.","family":"Walker","sequence":"first","affiliation":[{"name":"School of Chemistry and Molecular Biosciences and the Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy C.","family":"Barnett","sequence":"additional","affiliation":[{"name":"School of Chemistry and Molecular Biosciences and the Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason D.","family":"McArthur","sequence":"additional","affiliation":[{"name":"School of Biological Sciences and Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason N.","family":"Cole","sequence":"additional","affiliation":[{"name":"School of Chemistry and Molecular Biosciences and the Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD, Australia"},{"name":"Department of Pediatrics and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine M.","family":"Gillen","sequence":"additional","affiliation":[{"name":"School of Chemistry and Molecular Biosciences and the Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Henningham","sequence":"additional","affiliation":[{"name":"School of Chemistry and Molecular Biosciences and the Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD, Australia"},{"name":"Department of Pediatrics and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. S.","family":"Sriprakash","sequence":"additional","affiliation":[{"name":"QIMR Berghofer Medical Research Institute, Herston, Brisbane, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina L.","family":"Sanderson-Smith","sequence":"additional","affiliation":[{"name":"School of Biological Sciences and Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Nizet","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, USA"},{"name":"Rady Children's Hospital, San Diego, California, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.11.6.815"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/82_2012_284"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2008.08.037"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(09)70178-1"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(05)70267-X"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.13.3.470-511.2000"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00422-08"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1086\/341409"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/14.1.2"},{"key":"e_1_3_1_11_2","volume-title":"WHO report","author":"WHO","year":"2005","unstructured":"WHO. 2005. The current evidence for the burden of group A streptococcal diseases. WHO report. WHO, Geneva, Switzerland."},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5273(88)90003-4"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1983.03330310025020"},{"key":"e_1_3_1_14_2","first-page":"769","article-title":"Streptococcal diseases worldwide: present status and prospects","volume":"65","author":"Rotta J","year":"1987","unstructured":"Rotta J Tikhomirov E . 1987. Streptococcal diseases worldwide: present status and prospects. Bull. World Health Organ. 65:769\u2013777.","journal-title":"Bull. World Health Organ."},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198907063210101"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198702193160801"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400023135"},{"key":"e_1_3_1_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.1996.tb03454.x"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00747-08"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)90339-5"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2648"},{"key":"e_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1086\/657068"},{"key":"e_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00675-12"},{"key":"e_1_3_1_24_2","doi-asserted-by":"publisher","DOI":"10.1086\/502567"},{"key":"e_1_3_1_25_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00679-13"},{"key":"e_1_3_1_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31825874f3"},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis362"},{"key":"e_1_3_1_28_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.4.1559-1563.2004"},{"key":"e_1_3_1_29_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199201303260503"},{"key":"e_1_3_1_30_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199912000-00014"},{"key":"e_1_3_1_31_2","doi-asserted-by":"publisher","DOI":"10.1086\/520451"},{"key":"e_1_3_1_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/prca.200780048"},{"key":"e_1_3_1_33_2","doi-asserted-by":"publisher","DOI":"10.1586\/erv.09.133"},{"key":"e_1_3_1_34_2","doi-asserted-by":"publisher","DOI":"10.1086\/422697"},{"key":"e_1_3_1_35_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.152298499"},{"key":"e_1_3_1_36_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.071559398"},{"key":"e_1_3_1_37_2","doi-asserted-by":"publisher","DOI":"10.1086\/430618"},{"key":"e_1_3_1_38_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00672-08"},{"key":"e_1_3_1_39_2","doi-asserted-by":"publisher","DOI":"10.1101\/gr.1096703"},{"key":"e_1_3_1_40_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.062526099"},{"key":"e_1_3_1_41_2","doi-asserted-by":"publisher","DOI":"10.1086\/432514"},{"key":"e_1_3_1_42_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.12-226662"},{"key":"e_1_3_1_43_2","doi-asserted-by":"publisher","DOI":"10.1086\/315842"},{"key":"e_1_3_1_44_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.7.3101-3109.2005"},{"key":"e_1_3_1_45_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.1.373-378.2003"},{"key":"e_1_3_1_46_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.042309-0"},{"key":"e_1_3_1_47_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1711.110159"},{"key":"e_1_3_1_48_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268811001889"},{"key":"e_1_3_1_49_2","first-page":"110","article-title":"Group A Streptococcus virulence factors genes in north India & their association with emm type in pharyngitis","volume":"133","author":"Dhanda V","year":"2011","unstructured":"Dhanda V Vohra H Kumar R . 2011. Group A Streptococcus virulence factors genes in north India & their association with emm type in pharyngitis. Indian J. Med. Res. 133:110\u2013115. http:\/\/www.ijmr.org.in\/article.asp?issn=0971-5916;year=2011;volume=133;issue=1;spage=110;epage=115;aulast=Dhanda .","journal-title":"Indian J. Med. Res."},{"key":"e_1_3_1_50_2","doi-asserted-by":"publisher","DOI":"10.4103\/0971-5916.93437"},{"key":"e_1_3_1_51_2","first-page":"765","article-title":"Epidemiology of group A streptococcal pharyngitis & impetigo: a cross-sectional & follow up study in a rural community of northern India","volume":"130","author":"Kumar R","year":"2009","unstructured":"Kumar R Vohra H Chakraborty A Sharma YP Bandhopadhya S Dhanda V Sagar V Sharma M Shah B Ganguly NK . 2009. Epidemiology of group A streptococcal pharyngitis & impetigo: a cross-sectional & follow up study in a rural community of northern India. Indian J. Med. Res. 130:765\u2013771. http:\/\/icmr.nic.in\/ijmr\/2009\/december\/1215.pdf .","journal-title":"Indian J. Med. Res."},{"key":"e_1_3_1_52_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-9-115"},{"key":"e_1_3_1_53_2","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-39-3-165"},{"key":"e_1_3_1_54_2","doi-asserted-by":"publisher","DOI":"10.1086\/599344"},{"key":"e_1_3_1_55_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.12.4466-4471.2002"},{"key":"e_1_3_1_56_2","doi-asserted-by":"publisher","DOI":"10.1086\/318543"},{"key":"e_1_3_1_57_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0911295107"},{"key":"e_1_3_1_58_2","doi-asserted-by":"publisher","DOI":"10.1086\/513875"},{"key":"e_1_3_1_59_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/166.2.374"},{"key":"e_1_3_1_60_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-004-1147-z"},{"key":"e_1_3_1_61_2","doi-asserted-by":"publisher","DOI":"10.4161\/viru.2.5.16342"},{"key":"e_1_3_1_62_2","first-page":"329","article-title":"Pathogenesis of group A streptococcal infections","volume":"13","author":"Henningham A","year":"2012","unstructured":"Henningham A Barnett TC Maamary PG Walker MJ . 2012. Pathogenesis of group A streptococcal infections. Discov. Med. 13:329\u2013342. http:\/\/www.discoverymedicine.com\/Anna-Henningham\/2012\/05\/16\/pathogenesis-of-group-a-streptococcal-infections\/ .","journal-title":"Discov. Med."},{"key":"e_1_3_1_63_2","first-page":"383","article-title":"Diagnosis and treatment of streptococcal pharyngitis","volume":"79","author":"Choby BA","year":"2009","unstructured":"Choby BA . 2009. Diagnosis and treatment of streptococcal pharyngitis. Am. Fam. Physician 79:383\u2013390. http:\/\/www.aafp.org\/afp\/2009\/0301\/p383.pdf .","journal-title":"Am. Fam. Physician"},{"key":"e_1_3_1_64_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1009126"},{"key":"e_1_3_1_65_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-06839-3.00198-3"},{"key":"e_1_3_1_66_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/14.1.298"},{"key":"e_1_3_1_67_2","doi-asserted-by":"publisher","DOI":"10.1586\/eri.09.134"},{"key":"e_1_3_1_68_2","doi-asserted-by":"publisher","DOI":"10.1007\/82_2012_280"},{"key":"e_1_3_1_69_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/11.6.928"},{"key":"e_1_3_1_70_2","first-page":"859","article-title":"Diagnosis and treatment of impetigo","volume":"75","author":"Cole C","year":"2007","unstructured":"Cole C Gazewood J . 2007. Diagnosis and treatment of impetigo. Am. Fam. Physician 75:859\u2013864. http:\/\/www.aafp.org\/afp\/2007\/0315\/p859.pdf .","journal-title":"Am. Fam. Physician"},{"key":"e_1_3_1_71_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268807009740"},{"key":"e_1_3_1_72_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-73960-1_3"},{"key":"e_1_3_1_73_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1992.03490150121036"},{"key":"e_1_3_1_74_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2009.04.002"},{"key":"e_1_3_1_75_2","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e3283511d27"},{"key":"e_1_3_1_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-06839-3.00199-5"},{"key":"e_1_3_1_77_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2011.11-0185"},{"key":"e_1_3_1_78_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2007.01051.x"},{"key":"e_1_3_1_79_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2010.10.011"},{"key":"e_1_3_1_80_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2657"},{"key":"e_1_3_1_81_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2007.tb01054.x"},{"key":"e_1_3_1_82_2","doi-asserted-by":"publisher","DOI":"10.1086\/521264"},{"key":"e_1_3_1_83_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199608223350803"},{"key":"e_1_3_1_84_2","first-page":"93","volume-title":"Emerging infections 1","author":"Low DE","year":"1998","unstructured":"Low DE Schwartz B McGeer A . 1998. The reemergence of severe group A streptococcal disease: an evolutionary perspective, p 93\u2013123. In Scheld WM Armstrong D Hughes JM (ed), Emerging infections 1. ASM Press, Washington, DC."},{"key":"e_1_3_1_85_2","first-page":"157","article-title":"Invasive group A streptococcal disease","volume":"5","author":"Stevens DL","year":"1996","unstructured":"Stevens DL . 1996. Invasive group A streptococcal disease. Infect. Agents Dis. 5:157\u2013166.","journal-title":"Infect. Agents Dis."},{"key":"e_1_3_1_86_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2008.01225.x"},{"key":"e_1_3_1_87_2","doi-asserted-by":"publisher","DOI":"10.1086\/338466"},{"key":"e_1_3_1_88_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268898001952"},{"key":"e_1_3_1_89_2","first-page":"148","article-title":"Invasive group A streptococcal disease in north Queensland (1996-2001)","volume":"119","author":"Norton R","year":"2004","unstructured":"Norton R Smith HV Wood N Siegbrecht E Ross A Ketheesan N . 2004. Invasive group A streptococcal disease in north Queensland (1996-2001). Indian J. Med. Res. 119(Suppl):148\u2013151. http:\/\/icmr.nic.in\/ijmr\/ijmr_supp\/31.pdf .","journal-title":"Indian J. Med. Res."},{"key":"e_1_3_1_90_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268810001378"},{"key":"e_1_3_1_91_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa040275"},{"key":"e_1_3_1_92_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid15\/2.080558"},{"key":"e_1_3_1_93_2","doi-asserted-by":"publisher","DOI":"10.1017\/S095026880700917X"},{"key":"e_1_3_1_94_2","first-page":"14","article-title":"Outbreak of group A beta hemolytic Streptococcus pharyngitis in a Peruvian military facility, April 2012","volume":"20","author":"Ramos M","year":"2013","unstructured":"Ramos M Valle R Reaves EJ Loayza L Gonzalez S Bernal M Soto G Hawksworth AW Kasper MR Tilley DH De Mattos CA Brown JR Bausch DG . 2013. Outbreak of group A beta hemolytic Streptococcus pharyngitis in a Peruvian military facility, April 2012. MSMR 20:14\u201317.","journal-title":"MSMR"},{"key":"e_1_3_1_95_2","doi-asserted-by":"publisher","DOI":"10.1086\/597770"},{"key":"e_1_3_1_96_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2012.12.018"},{"key":"e_1_3_1_97_2","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-011-0166-9"},{"key":"e_1_3_1_98_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365540600868370"},{"key":"e_1_3_1_99_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00144817"},{"key":"e_1_3_1_100_2","first-page":"618","article-title":"A large food-borne outbreak of group A streptococcal pharyngitis in an industrial plant: potential for deliberate contamination","volume":"8","author":"Kaluski DN","year":"2006","unstructured":"Kaluski DN Barak E Kaufman Z Valinsky L Marva E Korenman Z Gorodnitzki Z Yishai R Koltai D Leventhal A Levine S Havkin O Green MS . 2006. A large food-borne outbreak of group A streptococcal pharyngitis in an industrial plant: potential for deliberate contamination. Isr. Med. Assoc. J. 8:618\u2013621. http:\/\/www.ima.org.il\/FilesUpload\/IMAJ\/0\/49\/24664.pdf .","journal-title":"Isr. Med. Assoc. J."},{"key":"e_1_3_1_101_2","doi-asserted-by":"publisher","DOI":"10.1086\/345670"},{"key":"e_1_3_1_102_2","doi-asserted-by":"publisher","DOI":"10.7883\/yoken.52.127"},{"key":"e_1_3_1_103_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365540510044085"},{"key":"e_1_3_1_104_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1410.071660"},{"key":"e_1_3_1_105_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2011.12.037"},{"key":"e_1_3_1_106_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0404163101"},{"key":"e_1_3_1_107_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0510279103"},{"key":"e_1_3_1_108_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0607669103"},{"key":"e_1_3_1_109_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1804.111803"},{"key":"e_1_3_1_110_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2011.07.003"},{"key":"e_1_3_1_111_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1810.120062"},{"key":"e_1_3_1_112_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1906.121020"},{"key":"e_1_3_1_113_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.8.4723-4731.2005"},{"key":"e_1_3_1_114_2","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00014-09"},{"key":"e_1_3_1_115_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.60.6.2147-2152.1992"},{"key":"e_1_3_1_116_2","first-page":"228","article-title":"Chemical properties and immunobiological activities of streptococcal lipoteichoic acids","volume":"259","author":"Hamada S","year":"1985","unstructured":"Hamada S Yamamoto T Koga T McGhee JR Michalek SM Yamamoto S . 1985. Chemical properties and immunobiological activities of streptococcal lipoteichoic acids. Zentralbl. Bakteriol. Mikrobiol. Hyg. A 259:228\u2013243.","journal-title":"Zentralbl. Bakteriol. Mikrobiol. Hyg. A"},{"key":"e_1_3_1_117_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1993.tb06169.x"},{"key":"e_1_3_1_118_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.184.8.2181-2191.2002"},{"key":"e_1_3_1_119_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.60.080805.142256"},{"key":"e_1_3_1_120_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0507808102"},{"key":"e_1_3_1_121_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.186.17.5865-5875.2004"},{"key":"e_1_3_1_122_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0015969"},{"key":"e_1_3_1_123_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2009.06727.x"},{"key":"e_1_3_1_124_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00071-10"},{"key":"e_1_3_1_125_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.239780"},{"key":"e_1_3_1_126_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.3.1159-1167.2002"},{"key":"e_1_3_1_127_2","doi-asserted-by":"publisher","DOI":"10.1086\/593176"},{"key":"e_1_3_1_128_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01301-06"},{"key":"e_1_3_1_129_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2007.00918.x"},{"key":"e_1_3_1_130_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2007.05704.x"},{"key":"e_1_3_1_131_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2008.06220.x"},{"key":"e_1_3_1_132_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1990.tb02072.x"},{"key":"e_1_3_1_133_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.8.4689"},{"key":"e_1_3_1_134_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.2.3.285"},{"key":"e_1_3_1_135_2","doi-asserted-by":"publisher","DOI":"10.1016\/0882-4010(92)90054-R"},{"key":"e_1_3_1_136_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.66.10.4593-4601.1998"},{"key":"e_1_3_1_137_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.5.5.826-830.1972"},{"key":"e_1_3_1_138_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.202671"},{"key":"e_1_3_1_139_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.62.2.442-448.1994"},{"key":"e_1_3_1_140_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2004.00497.x"},{"key":"e_1_3_1_141_2","doi-asserted-by":"publisher","DOI":"10.1006\/mpat.2001.0467"},{"key":"e_1_3_1_142_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.1993.tb00392.x"},{"key":"e_1_3_1_143_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1462-5822.2000.00076.x"},{"key":"e_1_3_1_144_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2001.02579.x"},{"key":"e_1_3_1_145_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2005.00618.x"},{"key":"e_1_3_1_146_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.7.2489"},{"key":"e_1_3_1_147_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1033.2003.03600.x"},{"key":"e_1_3_1_148_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2000.02084.x"},{"key":"e_1_3_1_149_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.mi.48.100194.003101"},{"key":"e_1_3_1_150_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12083"},{"key":"e_1_3_1_151_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature01589"},{"key":"e_1_3_1_152_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1995.tb07156.x"},{"key":"e_1_3_1_153_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.176.2.415"},{"key":"e_1_3_1_154_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2009.01864.x"},{"key":"e_1_3_1_155_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00300-08"},{"key":"e_1_3_1_156_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.2.993-997.2002"},{"key":"e_1_3_1_157_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2001.02535.x"},{"key":"e_1_3_1_158_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1999.01223.x"},{"key":"e_1_3_1_159_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1998.01097.x"},{"key":"e_1_3_1_160_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M806865200"},{"key":"e_1_3_1_161_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2007.05741.x"},{"key":"e_1_3_1_162_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2013.11.003"},{"key":"e_1_3_1_163_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1103966"},{"key":"e_1_3_1_164_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-842X(03)00098-2"},{"key":"e_1_3_1_165_2","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.10.28"},{"key":"e_1_3_1_166_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/173.4.896"},{"key":"e_1_3_1_167_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2009.03.002"},{"key":"e_1_3_1_168_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.187.12.4163-4172.2005"},{"key":"e_1_3_1_169_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M502896200"},{"key":"e_1_3_1_170_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.13.6172"},{"key":"e_1_3_1_171_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1995.mmi_17010137.x"},{"key":"e_1_3_1_172_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.63.2.622-631.1995"},{"key":"e_1_3_1_173_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268802006787"},{"key":"e_1_3_1_174_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2007.06006.x"},{"key":"e_1_3_1_175_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.186.1.110-121.2004"},{"key":"e_1_3_1_176_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.08-109348"},{"key":"e_1_3_1_177_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.65.6.2472-2474.1997"},{"key":"e_1_3_1_178_2","doi-asserted-by":"crossref","first-page":"375","DOI":"10.4049\/jimmunol.154.1.375","article-title":"Ig-binding surface proteins of Streptococcus pyogenes also bind human C4b-binding protein (C4BP), a regulatory component of the complement system","volume":"154","author":"Thern A","year":"1995","unstructured":"Thern A Stenberg L Dahlback B Lindahl G . 1995. Ig-binding surface proteins of Streptococcus pyogenes also bind human C4b-binding protein (C4BP), a regulatory component of the complement system. J. Immunol. 154:375\u2013386.","journal-title":"J. Immunol."},{"key":"e_1_3_1_179_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.167.7.3870"},{"key":"e_1_3_1_180_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2001.02664.x"},{"key":"e_1_3_1_181_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.5.1657"},{"key":"e_1_3_1_182_2","doi-asserted-by":"crossref","first-page":"4894","DOI":"10.4049\/jimmunol.161.9.4894","article-title":"Role of the hypervariable region in streptococcal M proteins: binding of a human complement inhibitor","volume":"161","author":"Johnsson E","year":"1998","unstructured":"Johnsson E Berggard K Kotarsky H Hellwage J Zipfel PF Sjobring U Lindahl G . 1998. Role of the hypervariable region in streptococcal M proteins: binding of a human complement inhibitor. J. Immunol. 161:4894\u20134901.","journal-title":"J. Immunol."},{"key":"e_1_3_1_183_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2005.04977.x"},{"key":"e_1_3_1_184_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.60.12.5036-5041.1992"},{"key":"e_1_3_1_185_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2005.04913.x"},{"key":"e_1_3_1_186_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2005.04527.x"},{"key":"e_1_3_1_187_2","doi-asserted-by":"publisher","DOI":"10.1159\/000353754"},{"key":"e_1_3_1_188_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2005.00662.x"},{"key":"e_1_3_1_189_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.64.5.1495-1501.1996"},{"key":"e_1_3_1_190_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.110.4.617"},{"key":"e_1_3_1_191_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2001.02635.x"},{"key":"e_1_3_1_192_2","doi-asserted-by":"publisher","DOI":"10.1086\/317635"},{"key":"e_1_3_1_193_2","doi-asserted-by":"publisher","DOI":"10.1086\/529194"},{"key":"e_1_3_1_194_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.31.18452"},{"key":"e_1_3_1_195_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.175.5.1291"},{"key":"e_1_3_1_196_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)74517-1"},{"key":"e_1_3_1_197_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)36494-4"},{"key":"e_1_3_1_198_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.180.18.4955-4959.1998"},{"key":"e_1_3_1_199_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)42330-1"},{"key":"e_1_3_1_200_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01317-12"},{"key":"e_1_3_1_201_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2007.03.011"},{"key":"e_1_3_1_202_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00191-10"},{"key":"e_1_3_1_203_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.65.1.64-71.1997"},{"key":"e_1_3_1_204_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.25.12238"},{"key":"e_1_3_1_205_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.62.2.433-441.1994"},{"key":"e_1_3_1_206_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.19.8317"},{"key":"e_1_3_1_207_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1462-5822.2000.00050.x"},{"key":"e_1_3_1_208_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00413-12"},{"key":"e_1_3_1_209_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2000.tb08999.x"},{"key":"e_1_3_1_210_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.2.1081"},{"key":"e_1_3_1_211_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2567.2001.01249.x"},{"key":"e_1_3_1_212_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.112039899"},{"key":"e_1_3_1_213_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.2.535-542.2000"},{"key":"e_1_3_1_214_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M301995200"},{"key":"e_1_3_1_215_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.9.4908-4916.2002"},{"key":"e_1_3_1_216_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0019-2805.2004.01837.x"},{"key":"e_1_3_1_217_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.7.3981-3986.2004"},{"key":"e_1_3_1_218_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.12.6701-6706.2003"},{"key":"e_1_3_1_219_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.11.6206-6214.2002"},{"key":"e_1_3_1_220_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2624"},{"key":"e_1_3_1_221_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.47.1.52-60.1985"},{"key":"e_1_3_1_222_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M804632200"},{"key":"e_1_3_1_223_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2002.02876.x"},{"key":"e_1_3_1_224_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0408721102"},{"key":"e_1_3_1_225_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(01)00198-2"},{"key":"e_1_3_1_226_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0803283"},{"key":"e_1_3_1_227_2","doi-asserted-by":"publisher","DOI":"10.1086\/432729"},{"key":"e_1_3_1_228_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.11.6384-6390.2000"},{"key":"e_1_3_1_229_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003455"},{"key":"e_1_3_1_230_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.7.4245-4254.2000"},{"key":"e_1_3_1_231_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.66.4.1671-1679.1998"},{"key":"e_1_3_1_232_2","doi-asserted-by":"publisher","DOI":"10.1086\/430617"},{"key":"e_1_3_1_233_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/122.6.517"},{"key":"e_1_3_1_234_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.67.10.5298-5305.1999"},{"key":"e_1_3_1_235_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1999.tb01509.x"},{"key":"e_1_3_1_236_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.1.446-455.2003"},{"key":"e_1_3_1_237_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.8.4851-4857.2001"},{"key":"e_1_3_1_238_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.12.4741"},{"key":"e_1_3_1_239_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1992.tb01557.x"},{"key":"e_1_3_1_240_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20030543"},{"key":"e_1_3_1_241_2","doi-asserted-by":"publisher","DOI":"10.1086\/314655"},{"key":"e_1_3_1_242_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.8.4786-4788.2000"},{"key":"e_1_3_1_243_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(02)02078-8"},{"key":"e_1_3_1_244_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm1201-1298"},{"key":"e_1_3_1_245_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.74.1.497-503.2006"},{"key":"e_1_3_1_246_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00499-13"},{"key":"e_1_3_1_247_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M410698200"},{"key":"e_1_3_1_248_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.11.7187-7189.2001"},{"key":"e_1_3_1_249_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.12.6646-6651.2002"},{"key":"e_1_3_1_250_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-11-120"},{"key":"e_1_3_1_251_2","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20130126"},{"key":"e_1_3_1_252_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2001.02269.x"},{"key":"e_1_3_1_253_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.65.5.1956-1959.1997"},{"key":"e_1_3_1_254_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.64.6.1913-1917.1996"},{"key":"e_1_3_1_255_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2000.02144.x"},{"key":"e_1_3_1_256_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.06-5804fje"},{"key":"e_1_3_1_257_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C400485200"},{"key":"e_1_3_1_258_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-2736(99)00198-4"},{"key":"e_1_3_1_259_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1101245"},{"key":"e_1_3_1_260_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.404582"},{"key":"e_1_3_1_261_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.120.3.1026-1032.1974"},{"key":"e_1_3_1_262_2","doi-asserted-by":"publisher","DOI":"10.1159\/000195749"},{"key":"e_1_3_1_263_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2000.tb09422.x"},{"key":"e_1_3_1_264_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.26.15598"},{"key":"e_1_3_1_265_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.187.19.6719-6725.2005"},{"key":"e_1_3_1_266_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0005366"},{"key":"e_1_3_1_267_2","doi-asserted-by":"publisher","DOI":"10.1086\/432485"},{"key":"e_1_3_1_268_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2008.07.002"},{"key":"e_1_3_1_269_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2010.07065.x"},{"key":"e_1_3_1_270_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)39748-0"},{"key":"e_1_3_1_271_2","doi-asserted-by":"publisher","DOI":"10.1086\/377700"},{"key":"e_1_3_1_272_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.53.2.432-434.1986"},{"key":"e_1_3_1_273_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.60.12.5219-5223.1992"},{"key":"e_1_3_1_274_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.1.350-359.2002"},{"key":"e_1_3_1_275_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M513408200"},{"key":"e_1_3_1_276_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1092385"},{"key":"e_1_3_1_277_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0406641102"},{"key":"e_1_3_1_278_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm1612"},{"key":"e_1_3_1_279_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2005.12.039"},{"key":"e_1_3_1_280_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002736"},{"key":"e_1_3_1_281_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2011.07550.x"},{"key":"e_1_3_1_282_2","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e3282f44c63"},{"key":"e_1_3_1_283_2","doi-asserted-by":"publisher","DOI":"10.1086\/653116"},{"key":"e_1_3_1_284_2","doi-asserted-by":"publisher","DOI":"10.2165\/11634180-000000000-00000"},{"key":"e_1_3_1_285_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2013.05.046"},{"key":"e_1_3_1_286_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-121808-102135"},{"key":"e_1_3_1_287_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2005.05.006"},{"key":"e_1_3_1_288_2","doi-asserted-by":"publisher","DOI":"10.1086\/593016"},{"key":"e_1_3_1_289_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2007.05.011"},{"key":"e_1_3_1_290_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm1202-800"},{"key":"e_1_3_1_291_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.178.5.3076"},{"key":"e_1_3_1_292_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(09)70066-0"},{"key":"e_1_3_1_293_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.5.3384"},{"key":"e_1_3_1_294_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI38095"},{"key":"e_1_3_1_295_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0020005"},{"key":"e_1_3_1_296_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.202353699"},{"key":"e_1_3_1_297_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.181.12.3649-3657.1999"},{"key":"e_1_3_1_298_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0337370100"},{"key":"e_1_3_1_299_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.173.2.1194"},{"key":"e_1_3_1_300_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1993.tb01180.x"},{"key":"e_1_3_1_301_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.23.8677"},{"key":"e_1_3_1_302_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.63.1.9-20.1995"},{"key":"e_1_3_1_303_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.11.6370-6377.2000"},{"key":"e_1_3_1_304_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2006.05381.x"},{"key":"e_1_3_1_305_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.172.2.696-700.1990"},{"key":"e_1_3_1_306_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0882-4010(96)80003-9"},{"key":"e_1_3_1_307_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.12250"},{"key":"e_1_3_1_308_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.8.4786"},{"key":"e_1_3_1_309_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1998.01057.x"},{"key":"e_1_3_1_310_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.186.12.3928-3937.2004"},{"key":"e_1_3_1_311_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2007.05649.x"},{"key":"e_1_3_1_312_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0636231100"},{"key":"e_1_3_1_313_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01560-08"},{"key":"e_1_3_1_314_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2006.01.005"},{"key":"e_1_3_1_315_2","doi-asserted-by":"publisher","DOI":"10.1159\/000317640"},{"key":"e_1_3_1_316_2","doi-asserted-by":"publisher","DOI":"10.1086\/319291"},{"key":"e_1_3_1_317_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004102"},{"key":"e_1_3_1_318_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000832"},{"key":"e_1_3_1_319_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.epidem.2011.07.001"},{"key":"e_1_3_1_320_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.1.364-370.2004"},{"key":"e_1_3_1_321_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-4-60"},{"key":"e_1_3_1_322_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.66.8.3931-3935.1998"},{"key":"e_1_3_1_323_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.66.2.771-776.1998"},{"key":"e_1_3_1_324_2","doi-asserted-by":"publisher","DOI":"10.1086\/653124"},{"key":"e_1_3_1_325_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061655"},{"key":"e_1_3_1_326_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.07-105643"},{"key":"e_1_3_1_327_2","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.9.10.7615163"},{"key":"e_1_3_1_328_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1978.tb12200.x"},{"key":"e_1_3_1_329_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0882-4010(95)90013-6"},{"key":"e_1_3_1_330_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2143(99)90095-1"},{"key":"e_1_3_1_331_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-230X(08)60028-7"},{"key":"e_1_3_1_332_2","doi-asserted-by":"publisher","DOI":"10.1160\/TH04-12-0842"},{"key":"e_1_3_1_333_2","doi-asserted-by":"publisher","DOI":"10.1016\/0305-0491(83)90345-0"},{"key":"e_1_3_1_334_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.281.5383.1662"},{"key":"e_1_3_1_335_2","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(95)00131-A"},{"key":"e_1_3_1_336_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003469"},{"key":"e_1_3_1_337_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1994.tb18865.x"},{"key":"e_1_3_1_338_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)74408-1"},{"key":"e_1_3_1_339_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M508758200"},{"key":"e_1_3_1_340_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01218-06"},{"key":"e_1_3_1_341_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M603846200"},{"key":"e_1_3_1_342_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.2001.4646"},{"key":"e_1_3_1_343_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-148-12-3933"},{"key":"e_1_3_1_344_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4899-1825-3_138"},{"key":"e_1_3_1_345_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01966-06"},{"key":"e_1_3_1_346_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2011.06.005"},{"key":"e_1_3_1_347_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2010.08.004"},{"key":"e_1_3_1_348_2","doi-asserted-by":"publisher","DOI":"10.1006\/mpat.1998.0207"},{"key":"e_1_3_1_349_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/171.1.85"},{"key":"e_1_3_1_350_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-144-1-119"},{"key":"e_1_3_1_351_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.09-131458"},{"key":"e_1_3_1_352_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.17.9862"},{"key":"e_1_3_1_353_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(04)00057-1"},{"key":"e_1_3_1_354_2","doi-asserted-by":"publisher","DOI":"10.1086\/323443"},{"key":"e_1_3_1_355_2","doi-asserted-by":"publisher","DOI":"10.1002\/1521-4141(200011)30:11<3247::AID-IMMU3247>3.0.CO;2-D"},{"key":"e_1_3_1_356_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2013.10.004"},{"key":"e_1_3_1_357_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.2008.00681.x"},{"key":"e_1_3_1_358_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2013.04.005"},{"key":"e_1_3_1_359_2","doi-asserted-by":"publisher","DOI":"10.4161\/viru.26400"},{"key":"e_1_3_1_360_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0066244"},{"key":"e_1_3_1_361_2","doi-asserted-by":"publisher","DOI":"10.1110\/ps.330101"},{"key":"e_1_3_1_362_2","doi-asserted-by":"publisher","DOI":"10.1110\/ps.9.9.1847"},{"key":"e_1_3_1_363_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/18.1.9"},{"key":"e_1_3_1_364_2","doi-asserted-by":"publisher","DOI":"10.1038\/74672"},{"key":"e_1_3_1_365_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1001149"},{"key":"e_1_3_1_366_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.61.8.3369-3374.1993"},{"key":"e_1_3_1_367_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.11.4941-4949.2003"},{"key":"e_1_3_1_368_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02155-08"},{"key":"e_1_3_1_369_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1999.01525.x"},{"key":"e_1_3_1_370_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.2011.02594.x"},{"key":"e_1_3_1_371_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-011-1385-9"},{"key":"e_1_3_1_372_2","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12276"},{"key":"e_1_3_1_373_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-07-170506"},{"key":"e_1_3_1_374_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.4.1903-1910.2003"},{"key":"e_1_3_1_375_2","doi-asserted-by":"publisher","DOI":"10.1042\/bj3050173"},{"key":"e_1_3_1_376_2","doi-asserted-by":"publisher","DOI":"10.1042\/bj3260657"},{"key":"e_1_3_1_377_2","doi-asserted-by":"publisher","DOI":"10.1086\/313827"},{"key":"e_1_3_1_378_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-10-182527"},{"key":"e_1_3_1_379_2","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2009.437"},{"key":"e_1_3_1_380_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.2006\/003285-0"},{"key":"e_1_3_1_381_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M610015200"},{"key":"e_1_3_1_382_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2010.04.032"},{"key":"e_1_3_1_383_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.2.1221"},{"key":"e_1_3_1_384_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2007.05841.x"},{"key":"e_1_3_1_385_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2013.05.003"},{"key":"e_1_3_1_386_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2011.01705.x"},{"key":"e_1_3_1_387_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003529"},{"key":"e_1_3_1_388_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-009-9332-6"},{"key":"e_1_3_1_389_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-385855-9.00002-3"},{"key":"e_1_3_1_390_2","doi-asserted-by":"publisher","DOI":"10.1080\/08916930500484674"},{"key":"e_1_3_1_391_2","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.4049\/jimmunol.143.8.2677","article-title":"Human and murine antibodies cross-reactive with streptococcal M protein and myosin recognize the sequence Gln-Lys-Ser-Lys-Gln in M protein","volume":"143","author":"Cunningham MW","year":"1989","unstructured":"Cunningham MW McCormack JM Fenderson PG Ho MK Beachey EH Dale JB . 1989. Human and murine antibodies cross-reactive with streptococcal M protein and myosin recognize the sequence Gln-Lys-Ser-Lys-Gln in M protein. J. Immunol. 143:2677\u20132683.","journal-title":"J. Immunol."},{"key":"e_1_3_1_392_2","doi-asserted-by":"crossref","first-page":"2760","DOI":"10.4049\/jimmunol.141.8.2760","article-title":"Human monoclonal antibodies reactive with antigens of the group A Streptococcus and human heart","volume":"141","author":"Cunningham MW","year":"1988","unstructured":"Cunningham MW McCormack JM Talaber LR Harley JB Ayoub EM Muneer RS Chun LT Reddy DV . 1988. Human monoclonal antibodies reactive with antigens of the group A Streptococcus and human heart. J. Immunol. 141:2760\u20132766.","journal-title":"J. Immunol."},{"key":"e_1_3_1_393_2","doi-asserted-by":"crossref","first-page":"3902","DOI":"10.4049\/jimmunol.151.7.3902","article-title":"A subset of mouse monoclonal antibodies cross-reactive with cytoskeletal proteins and group A streptococcal M proteins recognizes N-acetyl-beta-D-glucosamine","volume":"151","author":"Shikhman AR","year":"1993","unstructured":"Shikhman AR Greenspan NS Cunningham MW . 1993. A subset of mouse monoclonal antibodies cross-reactive with cytoskeletal proteins and group A streptococcal M proteins recognizes N-acetyl-beta-D-glucosamine. J. Immunol. 151:3902\u20133913.","journal-title":"J. Immunol."},{"key":"e_1_3_1_394_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.176.9.5662"},{"key":"e_1_3_1_395_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10753-013-9606-2"},{"key":"e_1_3_1_396_2","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e32835461d3"},{"key":"e_1_3_1_397_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2003.03352.x"},{"key":"e_1_3_1_398_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI17247"},{"key":"e_1_3_1_399_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M701047200"},{"key":"e_1_3_1_400_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2012.197"},{"key":"e_1_3_1_401_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm892"},{"key":"e_1_3_1_402_2","doi-asserted-by":"publisher","DOI":"10.1089\/cap.2010.0043"},{"key":"e_1_3_1_403_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.4.883"},{"key":"e_1_3_1_404_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.4.907"},{"key":"e_1_3_1_405_2","doi-asserted-by":"publisher","DOI":"10.1080\/08916930500484757"},{"key":"e_1_3_1_406_2","doi-asserted-by":"publisher","DOI":"10.2223\/JPED.1615"},{"key":"e_1_3_1_407_2","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-200306000-00017"},{"key":"e_1_3_1_408_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mp.4001542"},{"key":"e_1_3_1_409_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpn.2004.03.005"},{"key":"e_1_3_1_410_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-199507000-00006"},{"key":"e_1_3_1_411_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2796.1999.0438e.x"},{"key":"e_1_3_1_412_2","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e328337ba26"},{"key":"e_1_3_1_413_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-200103000-00003"},{"key":"e_1_3_1_414_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10165-008-0095-3"},{"key":"e_1_3_1_415_2","first-page":"1126","article-title":"Reactive arthritis associated with group C and group G beta-hemolytic streptococci","volume":"25","author":"Jansen TL","year":"1998","unstructured":"Jansen TL Janssen M de Jong AJ . 1998. Reactive arthritis associated with group C and group G beta-hemolytic streptococci. J. Rheumatol. 25:1126\u20131130.","journal-title":"J. Rheumatol."},{"key":"e_1_3_1_416_2","doi-asserted-by":"crossref","first-page":"3132","DOI":"10.4049\/jimmunol.146.9.3132","article-title":"Epitopes of group A streptococcal M protein shared with antigens of articular cartilage and synovium","volume":"146","author":"Baird RW","year":"1991","unstructured":"Baird RW Bronze MS Kraus W Hill HR Veasey LG Dale JB . 1991. Epitopes of group A streptococcal M protein shared with antigens of articular cartilage and synovium. J. Immunol. 146:3132\u20133137.","journal-title":"J. Immunol."},{"key":"e_1_3_1_417_2","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.39.687"},{"key":"e_1_3_1_418_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/120.2.258"},{"key":"e_1_3_1_419_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2005.00504.x"},{"key":"e_1_3_1_420_2","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-35-1-60"},{"key":"e_1_3_1_421_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000130624.94920.6B"},{"key":"e_1_3_1_422_2","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2008010092"},{"key":"e_1_3_1_423_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000133012.53669.1C"},{"key":"e_1_3_1_424_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5002169"},{"key":"e_1_3_1_425_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-80-3-342"},{"key":"e_1_3_1_426_2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2011.478"},{"key":"e_1_3_1_427_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0104-42302001000100034"},{"key":"e_1_3_1_428_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2001.tb143394.x"},{"key":"e_1_3_1_429_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268898001812"},{"key":"e_1_3_1_430_2","doi-asserted-by":"publisher","DOI":"10.1006\/mpat.1998.0244"},{"key":"e_1_3_1_431_2","doi-asserted-by":"publisher","DOI":"10.1086\/315882"},{"key":"e_1_3_1_432_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-51-7-589"},{"key":"e_1_3_1_433_2","doi-asserted-by":"publisher","DOI":"10.1159\/000091745"},{"key":"e_1_3_1_434_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2369-14-101"},{"key":"e_1_3_1_435_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis629"},{"key":"e_1_3_1_436_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(85)80228-6"},{"key":"e_1_3_1_437_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(51)90274-4"},{"key":"e_1_3_1_438_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(54)90219-3"},{"key":"e_1_3_1_439_2","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1542\/peds.96.4.758","article-title":"Treatment of acute streptococcal pharyngitis and prevention of rheumatic fever: a statement for health professionals. Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young, the American Heart Association","volume":"96","author":"Dajani A","year":"1995","unstructured":"Dajani A Taubert K Ferrieri P Peter G Shulman S . 1995. Treatment of acute streptococcal pharyngitis and prevention of rheumatic fever: a statement for health professionals. Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young, the American Heart Association. Pediatrics 96:758\u2013764.","journal-title":"Pediatrics"},{"key":"e_1_3_1_440_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199912000-00008"},{"key":"e_1_3_1_441_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.97.6.971"},{"key":"e_1_3_1_442_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.6.1727-1731.1999"},{"key":"e_1_3_1_443_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa013169"},{"key":"e_1_3_1_444_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkf811"},{"key":"e_1_3_1_445_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(98)00150-9"},{"key":"e_1_3_1_446_2","first-page":"153","article-title":"Failure of once-daily penicillin V therapy for streptococcal pharyngitis","volume":"143","author":"Gerber MA","year":"1989","unstructured":"Gerber MA Randolph MF DeMeo K Feder HM Jr Kaplan EL . 1989. Failure of once-daily penicillin V therapy for streptococcal pharyngitis. Am. J. Dis. Child. 143:153\u2013155.","journal-title":"Am. J. Dis. Child."},{"key":"e_1_3_1_447_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2007.04.010"},{"key":"e_1_3_1_448_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000138080.74674.a2"},{"key":"e_1_3_1_449_2","doi-asserted-by":"publisher","DOI":"10.1177\/000992280304200606"},{"key":"e_1_3_1_450_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2006.113506"},{"key":"e_1_3_1_451_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008480-200102000-00009"},{"key":"e_1_3_1_452_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.64.6.904"},{"key":"e_1_3_1_453_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-0133"},{"key":"e_1_3_1_454_2","doi-asserted-by":"publisher","DOI":"10.1086\/342692"},{"key":"e_1_3_1_455_2","first-page":"668","volume-title":"Red book: 2012 report of the Committee on Infectious Diseases","author":"American Academy of Pediatrics","year":"2012","unstructured":"American Academy of Pediatrics. 2012. Group A streptococcal infections, p 668\u2013680. In Pickering LK Baker CJ Kimberlin DW Long SS (ed), Red book: 2012 report of the Committee on Infectious Diseases. American Academy of Pediatrics, Elk Grove Village, IL."},{"key":"e_1_3_1_456_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2013.03.003"},{"key":"e_1_3_1_457_2","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.6.2.155"},{"key":"e_1_3_1_458_2","doi-asserted-by":"publisher","DOI":"10.1086\/497143"},{"key":"e_1_3_1_459_2","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/585187"},{"key":"e_1_3_1_460_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/158.1.23"},{"key":"e_1_3_1_461_2","doi-asserted-by":"publisher","DOI":"10.1086\/515199"},{"key":"e_1_3_1_462_2","doi-asserted-by":"publisher","DOI":"10.1086\/376630"},{"key":"e_1_3_1_463_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003176.pub2"},{"key":"e_1_3_1_464_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61171-9"},{"key":"e_1_3_1_465_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.191959"},{"key":"e_1_3_1_466_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66874-2"},{"key":"e_1_3_1_467_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198209163071205"},{"key":"e_1_3_1_468_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199805000-00006"},{"key":"e_1_3_1_469_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.04938-0"},{"key":"e_1_3_1_470_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2004.03.008"},{"key":"e_1_3_1_471_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.1999.5.219"},{"key":"e_1_3_1_472_2","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.20"},{"key":"e_1_3_1_473_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2011.02252.x"},{"key":"e_1_3_1_474_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(80)91832-2"},{"key":"e_1_3_1_475_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.5.1180"},{"key":"e_1_3_1_476_2","doi-asserted-by":"publisher","DOI":"10.1086\/508773"},{"key":"e_1_3_1_477_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)12452-7"},{"key":"e_1_3_1_478_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100122893"},{"key":"e_1_3_1_479_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00512-06"},{"key":"e_1_3_1_480_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2011.03.009"},{"key":"e_1_3_1_481_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/6.5.601"},{"key":"e_1_3_1_482_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2007.00610.x"},{"key":"e_1_3_1_483_2","doi-asserted-by":"publisher","DOI":"10.1086\/513854"},{"key":"e_1_3_1_484_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00461-08"},{"key":"e_1_3_1_485_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.170.10.4775-4783.1988"},{"key":"e_1_3_1_486_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.19.5.872"},{"key":"e_1_3_1_487_2","first-page":"181","article-title":"Investigation of penicillin resistant streptococci belonging to group A","volume":"39","author":"Rosendal K","year":"1957","unstructured":"Rosendal K . 1957. Investigation of penicillin resistant streptococci belonging to group A. Acta Pathol. Microbiol. Scand. 39:181\u2013188.","journal-title":"Acta Pathol. Microbiol. Scand."},{"key":"e_1_3_1_488_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.85.6.1280-1287.1963"},{"key":"e_1_3_1_489_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.22.1.128"},{"key":"e_1_3_1_490_2","doi-asserted-by":"publisher","DOI":"10.1086\/516375"},{"key":"e_1_3_1_491_2","doi-asserted-by":"publisher","DOI":"10.2217\/17460913.2.3.323"},{"key":"e_1_3_1_492_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4419-8993-2_25"},{"key":"e_1_3_1_493_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/20.Supplement_2.S154"},{"key":"e_1_3_1_494_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/42.2.257"},{"key":"e_1_3_1_495_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1996.01521.x"},{"key":"e_1_3_1_496_2","doi-asserted-by":"publisher","DOI":"10.1086\/432473"},{"key":"e_1_3_1_497_2","doi-asserted-by":"publisher","DOI":"10.3343\/kjlm.2010.30.5.485"},{"key":"e_1_3_1_498_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20976"},{"key":"e_1_3_1_499_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01054-06"},{"key":"e_1_3_1_500_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01665-10"},{"key":"e_1_3_1_501_2","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2005.11.360"},{"key":"e_1_3_1_502_2","doi-asserted-by":"publisher","DOI":"10.1086\/501460"},{"key":"e_1_3_1_503_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.1.159-164.2002"},{"key":"e_1_3_1_504_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199708143370701"},{"key":"e_1_3_1_505_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.9.3559-3562.2004"},{"key":"e_1_3_1_506_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-011-1362-3"},{"key":"e_1_3_1_507_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks281"},{"key":"e_1_3_1_508_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq006"},{"key":"e_1_3_1_509_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.5.2109-2111.2005"},{"key":"e_1_3_1_510_2","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.65.2.232-260.2001"},{"key":"e_1_3_1_511_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.178.11.3246-3251.1996"},{"key":"e_1_3_1_512_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms2470"},{"key":"e_1_3_1_513_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.11.4798-4800.2005"},{"key":"e_1_3_1_514_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-8579(03)00062-1"},{"key":"e_1_3_1_515_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01341-06"},{"key":"e_1_3_1_516_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01484-06"},{"key":"e_1_3_1_517_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00499-09"},{"key":"e_1_3_1_518_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-842X(00)88930-1"},{"key":"e_1_3_1_519_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.9.2844-2849.2003"},{"key":"e_1_3_1_520_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.05352-11"},{"key":"e_1_3_1_521_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.2.788-790.2005"},{"key":"e_1_3_1_522_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00780-09"},{"key":"e_1_3_1_523_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.45.12.3334-3340.2001"},{"key":"e_1_3_1_524_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.2008\/002642-0"},{"key":"e_1_3_1_525_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2008.04.018"},{"key":"e_1_3_1_526_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2006.12.016"},{"key":"e_1_3_1_527_2","doi-asserted-by":"publisher","DOI":"10.1086\/345904"},{"key":"e_1_3_1_528_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.50.3.943-948.2006"},{"key":"e_1_3_1_529_2","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12134"},{"key":"e_1_3_1_530_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-148-1-169"},{"key":"e_1_3_1_531_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/138.6.712"},{"key":"e_1_3_1_532_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI107372"},{"key":"e_1_3_1_533_2","first-page":"217","article-title":"Protective studies with a group A streptococcal M protein vaccine. II","volume":"131","author":"Polly SM","year":"1975","unstructured":"Polly SM Waldman RH High P Wittner MK Dorfman A . 1975. Protective studies with a group A streptococcal M protein vaccine. II. Challenge of volunteers after local immunization in the upper respiratory tract. J. Infect. Dis. 131:217\u2013224.","journal-title":"Challenge of volunteers after local immunization in the upper respiratory tract. J. Infect. Dis."},{"key":"e_1_3_1_534_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1969.03150190037007"},{"key":"e_1_3_1_535_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.163.6.1451"},{"key":"e_1_3_1_536_2","doi-asserted-by":"publisher","DOI":"10.1038\/292457a0"},{"key":"e_1_3_1_537_2","doi-asserted-by":"crossref","first-page":"2188","DOI":"10.4049\/jimmunol.151.4.2188","article-title":"Recombinant tetravalent group A streptococcal M protein vaccine","volume":"151","author":"Dale JB","year":"1993","unstructured":"Dale JB Chiang EY Lederer JW . 1993. Recombinant tetravalent group A streptococcal M protein vaccine. J. Immunol. 151:2188\u20132194.","journal-title":"J. Immunol."},{"key":"e_1_3_1_538_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.158.5.1727"},{"key":"e_1_3_1_539_2","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410X(96)00050-3"},{"key":"e_1_3_1_540_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.6.709"},{"key":"e_1_3_1_541_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.5.2507-2512.2004"},{"key":"e_1_3_1_542_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.4.2171-2177.2002"},{"key":"e_1_3_1_543_2","doi-asserted-by":"publisher","DOI":"10.1086\/444458"},{"key":"e_1_3_1_544_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.09.005"},{"key":"e_1_3_1_545_2","doi-asserted-by":"publisher","DOI":"10.1086\/503422"},{"key":"e_1_3_1_546_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268807007984"},{"key":"e_1_3_1_547_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268809002805"},{"key":"e_1_3_1_548_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.2660266"},{"key":"e_1_3_1_549_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.6.3444-3450.2004"},{"key":"e_1_3_1_550_2","doi-asserted-by":"publisher","DOI":"10.1086\/374800"},{"key":"e_1_3_1_551_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.12.115"},{"key":"e_1_3_1_552_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.56.10.2666-2672.1988"},{"key":"e_1_3_1_553_2","doi-asserted-by":"publisher","DOI":"10.1038\/74719"},{"key":"e_1_3_1_554_2","doi-asserted-by":"crossref","first-page":"888","DOI":"10.4049\/jimmunol.148.3.888","article-title":"Epitopes of group A streptococcal M protein that evoke cross-protective local immune responses","volume":"148","author":"Bronze MS","year":"1992","unstructured":"Bronze MS Courtney HS Dale JB . 1992. Epitopes of group A streptococcal M protein that evoke cross-protective local immune responses. J. Immunol. 148:888\u2013893.","journal-title":"J. Immunol."},{"key":"e_1_3_1_555_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2009.08.049"},{"key":"e_1_3_1_556_2","doi-asserted-by":"publisher","DOI":"10.1080\/17402520600877026"},{"key":"e_1_3_1_557_2","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/9.11.1723"},{"key":"e_1_3_1_558_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.05.075"},{"key":"e_1_3_1_559_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1202333"},{"key":"e_1_3_1_560_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0060969"},{"key":"e_1_3_1_561_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2007.01.079"},{"key":"e_1_3_1_562_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/171.3.593"},{"key":"e_1_3_1_563_2","doi-asserted-by":"publisher","DOI":"10.1086\/498618"},{"key":"e_1_3_1_564_2","doi-asserted-by":"publisher","DOI":"10.1038\/213044a0"},{"key":"e_1_3_1_565_2","doi-asserted-by":"publisher","DOI":"10.1038\/cmi.2009.10"},{"key":"e_1_3_1_566_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.9.5097-5103.2003"},{"key":"e_1_3_1_567_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.2.924-930.2001"},{"key":"e_1_3_1_568_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1999.01470.x"},{"key":"e_1_3_1_569_2","doi-asserted-by":"publisher","DOI":"10.1086\/315693"},{"key":"e_1_3_1_570_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI5118"},{"key":"e_1_3_1_571_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2004.04.030"},{"key":"e_1_3_1_572_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.65.6.2080-2087.1997"},{"key":"e_1_3_1_573_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.12.7878-7886.2005"},{"key":"e_1_3_1_574_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir149"},{"key":"e_1_3_1_575_2","doi-asserted-by":"publisher","DOI":"10.1006\/mpat.1994.1044"},{"key":"e_1_3_1_576_2","doi-asserted-by":"publisher","DOI":"10.1186\/1476-8518-6-8"},{"key":"e_1_3_1_577_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00038-07"},{"key":"e_1_3_1_578_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2005.02.035"},{"key":"e_1_3_1_579_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2009.06.042"},{"key":"e_1_3_1_580_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-012-0897-9"},{"key":"e_1_3_1_581_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.12.7342-7345.2004"},{"key":"e_1_3_1_582_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M706739200"},{"key":"e_1_3_1_583_2","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M111.015693"},{"key":"e_1_3_1_584_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00387-12"},{"key":"e_1_3_1_585_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00509-13"},{"key":"e_1_3_1_586_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1369-5274(00)00119-3"},{"key":"e_1_3_1_587_2","doi-asserted-by":"publisher","DOI":"10.1021\/pr3005265"},{"key":"e_1_3_1_588_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00295-10"},{"key":"e_1_3_1_589_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1179"},{"key":"e_1_3_1_590_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.169.1.269"},{"key":"e_1_3_1_591_2","doi-asserted-by":"publisher","DOI":"10.1086\/499812"},{"key":"e_1_3_1_592_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199109123251106"},{"key":"e_1_3_1_593_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.2274"},{"key":"e_1_3_1_594_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit282"},{"key":"e_1_3_1_595_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e4955"},{"key":"e_1_3_1_596_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0062433"},{"key":"e_1_3_1_597_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2011.07749.x"},{"key":"e_1_3_1_598_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1994.tb00448.x"},{"key":"e_1_3_1_599_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1996.6331356.x"},{"key":"e_1_3_1_600_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.67.6.2720-2728.1999"},{"key":"e_1_3_1_601_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M209133200"},{"key":"e_1_3_1_602_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.185.4.1208-1217.2003"},{"key":"e_1_3_1_603_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.62.9.3937-3946.1994"},{"key":"e_1_3_1_604_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.12.6542-6553.2000"},{"key":"e_1_3_1_605_2","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-147-2-419"},{"key":"e_1_3_1_606_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.3.1042-1055.2003"},{"key":"e_1_3_1_607_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.174.16.5204-5210.1992"}],"container-title":["Clinical Microbiology Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/CMR.00101-13","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/CMR.00101-13","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T15:08:50Z","timestamp":1689088130000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/CMR.00101-13"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":606,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1128\/CMR.00101-13"],"URL":"https:\/\/doi.org\/10.1128\/cmr.00101-13","relation":{},"ISSN":["0893-8512","1098-6618"],"issn-type":[{"value":"0893-8512","type":"print"},{"value":"1098-6618","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4]]},"assertion":[{"value":"2014-04-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}