{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T17:42:45Z","timestamp":1792172565635,"version":"4.4.0"},"reference-count":430,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T00:00:00Z","timestamp":1412121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Microbiol Rev"],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>\n                    The brain is well protected against microbial invasion by cellular barriers, such as the blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). In addition, cells within the central nervous system (CNS) are capable of producing an immune response against invading pathogens. Nonetheless, a range of pathogenic microbes make their way to the CNS, and the resulting infections can cause significant morbidity and mortality. Bacteria, amoebae, fungi, and viruses are capable of CNS invasion, with the latter using axonal transport as a common route of infection. In this review, we compare the mechanisms by which bacterial pathogens reach the CNS and infect the brain. In particular, we focus on recent data regarding mechanisms of bacterial translocation from the nasal mucosa to the brain, which represents a little explored pathway of bacterial invasion but has been proposed as being particularly important in explaining how infection with\n                    <jats:named-content content-type=\"genus-species\">Burkholderia pseudomallei<\/jats:named-content>\n                    can result in melioidosis encephalomyelitis.\n                  <\/jats:p>","DOI":"10.1128\/cmr.00118-13","type":"journal-article","created":{"date-parts":[[2014,10,2]],"date-time":"2014-10-02T11:15:33Z","timestamp":1412248533000},"page":"691-726","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":415,"title":["Pathogens Penetrating the Central Nervous System: Infection Pathways and the Cellular and Molecular Mechanisms of Invasion"],"prefix":"10.1128","volume":"27","author":[{"given":"Samantha J.","family":"Dando","sequence":"first","affiliation":[{"name":"Institute for Glycomics, Griffith University, Gold Coast, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Mackay-Sim","sequence":"additional","affiliation":[{"name":"Eskitis Institute for Drug Discovery, Griffith University, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Norton","sequence":"additional","affiliation":[{"name":"Townsville Hospital, Townsville, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart J.","family":"Currie","sequence":"additional","affiliation":[{"name":"Menzies School of Health Research and Royal Darwin Hospital, Darwin, Northern Territory, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James A.","family":"St. John","sequence":"additional","affiliation":[{"name":"Eskitis Institute for Drug Discovery, Griffith University, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny A. K.","family":"Ekberg","sequence":"additional","affiliation":[{"name":"Eskitis Institute for Drug Discovery, Griffith University, Brisbane, Queensland, Australia"},{"name":"School of Biomedical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Batzloff","sequence":"additional","affiliation":[{"name":"Institute for Glycomics, Griffith University, Gold Coast, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glen C.","family":"Ulett","sequence":"additional","affiliation":[{"name":"School of Medical Science and Griffith Health Institute, Griffith University, Gold Coast, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ifor R.","family":"Beacham","sequence":"additional","affiliation":[{"name":"Institute for Glycomics, Griffith University, Gold Coast, Queensland, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(20)30368-8"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2012.02.010"},{"key":"e_1_3_1_4_2","first-page":"58","volume-title":"Infections of the central nervous system","author":"Cassady KA","year":"2004","unstructured":"Cassady KA Whitley RJ . 2004. Pathogenesis and pathophysiology of viral infections of the central nervous system, p 58\u201360. In Scheld WM Whitley RJ Marra CM (ed), Infections of the central nervous system, 3rd ed. Lippincott Williams & Wilkins, Philadelphia, PA.","edition":"3"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2012.03.019"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri2971"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(10)70222-X"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1086\/509330"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199301073280104"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-200011000-00002"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-010-9396-4"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa040845"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/162.6.1316"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1985.03350360075022"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1005384"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(13)70332-3"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0042099"},{"key":"e_1_3_1_18_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1079\/9781780641621.0000","volume-title":"Meningitis: cellular and molecular basis","author":"Christodoulides M","year":"2013","unstructured":"Christodoulides M . 2013. A history of bacterial meningitis from antiquity to modern times, p 1\u201316. In Christodoulides M (ed), Meningitis: cellular and molecular basis. CAB International, Wallingford, Oxfordshire, United Kingdom."},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.12107"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/783698"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI115965"},{"key":"e_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1086\/524874"},{"key":"e_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.76.6.901"},{"key":"e_1_3_1_24_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.69.6.699"},{"key":"e_1_3_1_25_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-5-93"},{"key":"e_1_3_1_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01071-08"},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002027"},{"key":"e_1_3_1_28_2","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00393-12"},{"key":"e_1_3_1_29_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00862-12"},{"key":"e_1_3_1_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.05418-11"},{"key":"e_1_3_1_31_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002521"},{"key":"e_1_3_1_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-06839-3.00084-9"},{"key":"e_1_3_1_33_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0800836"},{"key":"e_1_3_1_34_2","first-page":"1","article-title":"Australia's notifiable disease status, 2010: annual report of the National Notifiable Diseases Surveillance System","volume":"36","author":"Milton A","year":"2012","unstructured":"Milton A Stirzaker S Trungove M Knuckey D Martin N Hastie C Pennington K Sloan-Gardner T Fitzsimmons G Knope K Martinek S Mills L Barry C Wright P Power M . 2012. Australia's notifiable disease status, 2010: annual report of the National Notifiable Diseases Surveillance System. Commun. Dis. Intell. Q. Rep. 36:1\u201369.","journal-title":"Commun. Dis. Intell. Q. Rep."},{"key":"e_1_3_1_35_2","doi-asserted-by":"publisher","DOI":"10.1017\/S095026881200218X"},{"key":"e_1_3_1_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(11)70090-1"},{"key":"e_1_3_1_37_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0071943"},{"key":"e_1_3_1_38_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-13-576"},{"key":"e_1_3_1_39_2","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/978-1-61779-346-2_2","volume-title":"Neisseria meningitidis: advanced methods and protocols","author":"Brandtzaeg P","year":"2012","unstructured":"Brandtzaeg P van Deuren M . 2012. Classification and pathogenesis of meningococcal infections, p 21\u201335. In Christodoulides M (ed), Neisseria meningitidis: advanced methods and protocols, vol 799. Humana Press, New York, NY."},{"key":"e_1_3_1_40_2","first-page":"220","article-title":"Meningococcal serogroup C conjugate vaccination in England and Wales: coverage and initial impact of the campaign","volume":"5","author":"Trotter CL","year":"2002","unstructured":"Trotter CL Ramsay ME Kaczmarski EB . 2002. Meningococcal serogroup C conjugate vaccination in England and Wales: coverage and initial impact of the campaign. Commun. Dis. Public Health 5:220\u2013225.","journal-title":"Commun. Dis. Public Health"},{"key":"e_1_3_1_41_2","first-page":"E251","article-title":"Annual report of the Australian Meningococcal Surveillance Programme, 2011","volume":"36","author":"Lahra MM","year":"2012","unstructured":"Lahra MM Enriquez RP . 2012. Annual report of the Australian Meningococcal Surveillance Programme, 2011. Commun. Dis. Intell. Q. Rep. 36:E251\u2013E262.","journal-title":"Commun. Dis. Intell. Q. Rep."},{"key":"e_1_3_1_42_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyn228"},{"key":"e_1_3_1_43_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-10-324"},{"key":"e_1_3_1_44_2","doi-asserted-by":"publisher","DOI":"10.1086\/508462"},{"key":"e_1_3_1_45_2","doi-asserted-by":"publisher","DOI":"10.1086\/511695"},{"key":"e_1_3_1_46_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000225"},{"key":"e_1_3_1_47_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181fab1e7"},{"key":"e_1_3_1_48_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr.11.2011.5137"},{"key":"e_1_3_1_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2012.07.006"},{"key":"e_1_3_1_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-06839-3.00086-2"},{"key":"e_1_3_1_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70168-6"},{"key":"e_1_3_1_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2004.02.010"},{"key":"e_1_3_1_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-06839-3.00087-4"},{"key":"e_1_3_1_54_2","doi-asserted-by":"publisher","DOI":"10.3109\/00365548.2012.719634"},{"key":"e_1_3_1_55_2","first-page":"192","article-title":"Encephalitis in Australia, 1979-2006: trends and aetiologies","volume":"33","author":"Huppatz C","year":"2009","unstructured":"Huppatz C Kelly PM Levi C Dalton C Williams D Durrheim DN . 2009. Encephalitis in Australia, 1979-2006: trends and aetiologies. Commun. Dis. Intell. Q. Rep. 33:192\u2013197.","journal-title":"Commun. Dis. Intell. Q. Rep."},{"key":"e_1_3_1_56_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0071671"},{"key":"e_1_3_1_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-706X(99)00064-9"},{"key":"e_1_3_1_58_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000900"},{"key":"e_1_3_1_59_2","first-page":"195","article-title":"The neuropathology of melioidosis: two cases and a review of the literature","volume":"23","author":"Koszyca B","year":"2004","unstructured":"Koszyca B Currie BJ Blumbergs PC . 2004. The neuropathology of melioidosis: two cases and a review of the literature. Clin. Neuropathol. 23:195\u2013203.","journal-title":"Clin. Neuropathol."},{"key":"e_1_3_1_60_2","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/15.1.163"},{"key":"e_1_3_1_61_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(99)90299-7"},{"key":"e_1_3_1_62_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1998.tb02978.x"},{"key":"e_1_3_1_63_2","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X9702500213"},{"key":"e_1_3_1_64_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(02)90248-8"},{"key":"e_1_3_1_65_2","doi-asserted-by":"publisher","DOI":"10.3171\/2013.5.JNS12555"},{"key":"e_1_3_1_66_2","doi-asserted-by":"publisher","DOI":"10.1086\/515541"},{"key":"e_1_3_1_67_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-06839-3.00088-6"},{"key":"e_1_3_1_68_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000172"},{"key":"e_1_3_1_69_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2005.12.002"},{"key":"e_1_3_1_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-06839-3.00089-8"},{"key":"e_1_3_1_71_2","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1079\/9781780641621.0017","volume-title":"Meningitis: cellular and molecular basis","author":"Weller RO","year":"2013","unstructured":"Weller RO . 2013. Anatomy of the meninges: structural and functional aspects, p 17\u201330. In Christodoulides M (ed), Meningitis: cellular and molecular basis. CAB International, Wallingford, Oxfordshire, United Kingdom."},{"key":"e_1_3_1_72_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.2006.00737.x"},{"key":"e_1_3_1_73_2","doi-asserted-by":"publisher","DOI":"10.1186\/1743-8454-1-2"},{"key":"e_1_3_1_74_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4614-3235-7_8"},{"key":"e_1_3_1_75_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10545-013-9608-0"},{"key":"e_1_3_1_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2009.07.030"},{"key":"e_1_3_1_77_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-009-0177-0"},{"key":"e_1_3_1_78_2","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2013.175"},{"key":"e_1_3_1_79_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2011.07208.x"},{"key":"e_1_3_1_80_2","doi-asserted-by":"publisher","DOI":"10.1021\/mp200129p"},{"key":"e_1_3_1_81_2","doi-asserted-by":"publisher","DOI":"10.1186\/2045-8118-8-3"},{"key":"e_1_3_1_82_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn2014"},{"key":"e_1_3_1_83_2","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2887"},{"key":"e_1_3_1_84_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1194637"},{"key":"e_1_3_1_85_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1110647"},{"key":"e_1_3_1_86_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-010-0774-y"},{"key":"e_1_3_1_87_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.21668"},{"key":"e_1_3_1_88_2","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(96)00160-1"},{"key":"e_1_3_1_89_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20102657"},{"key":"e_1_3_1_90_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri3265"},{"key":"e_1_3_1_91_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1433000100"},{"key":"e_1_3_1_92_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21379"},{"key":"e_1_3_1_93_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2012.07.004"},{"key":"e_1_3_1_94_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0967-12.2012"},{"key":"e_1_3_1_95_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2012.06.054"},{"key":"e_1_3_1_96_2","doi-asserted-by":"publisher","DOI":"10.1080\/00207450802479970"},{"key":"e_1_3_1_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(00)00402-1"},{"key":"e_1_3_1_98_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.2.845-852.2001"},{"key":"e_1_3_1_99_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI12035"},{"key":"e_1_3_1_100_2","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/312476"},{"key":"e_1_3_1_101_2","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e32833950dd"},{"key":"e_1_3_1_102_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3029"},{"key":"e_1_3_1_103_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI113395"},{"key":"e_1_3_1_104_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.2008\/017988-0"},{"key":"e_1_3_1_105_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068408"},{"key":"e_1_3_1_106_2","doi-asserted-by":"publisher","DOI":"10.1086\/599210"},{"key":"e_1_3_1_107_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3639.2001.tb00411.x"},{"key":"e_1_3_1_108_2","doi-asserted-by":"publisher","DOI":"10.1002\/glia.21256"},{"key":"e_1_3_1_109_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.1.221-227.2001"},{"key":"e_1_3_1_110_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms1474"},{"key":"e_1_3_1_111_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms1554"},{"key":"e_1_3_1_112_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiq047"},{"key":"e_1_3_1_113_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.0030059"},{"key":"e_1_3_1_114_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0914257107"},{"key":"e_1_3_1_115_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0083345"},{"key":"e_1_3_1_116_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-381361-9.00020-2"},{"key":"e_1_3_1_117_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4707-08.2009"},{"key":"e_1_3_1_118_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0025016"},{"key":"e_1_3_1_119_2","doi-asserted-by":"publisher","DOI":"10.1086\/502631"},{"key":"e_1_3_1_120_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12121"},{"key":"e_1_3_1_121_2","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2009.72"},{"key":"e_1_3_1_122_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0038149"},{"key":"e_1_3_1_123_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000314"},{"key":"e_1_3_1_124_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00369-12"},{"key":"e_1_3_1_125_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20060482"},{"key":"e_1_3_1_126_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2012.07.020"},{"key":"e_1_3_1_127_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-3458fje"},{"key":"e_1_3_1_128_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2005.10.014"},{"key":"e_1_3_1_129_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.22232"},{"key":"e_1_3_1_130_2","doi-asserted-by":"publisher","DOI":"10.1186\/2045-8118-10-33"},{"key":"e_1_3_1_131_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature09513"},{"key":"e_1_3_1_132_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.09.043"},{"key":"e_1_3_1_133_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature09522"},{"key":"e_1_3_1_134_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm889"},{"key":"e_1_3_1_135_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2007.02.029"},{"key":"e_1_3_1_136_2","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2012.45"},{"key":"e_1_3_1_137_2","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhs198"},{"key":"e_1_3_1_138_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-0320-7_33"},{"key":"e_1_3_1_139_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2011.05.012"},{"key":"e_1_3_1_140_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2008.12.002"},{"key":"e_1_3_1_141_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0030069"},{"key":"e_1_3_1_142_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0039835"},{"key":"e_1_3_1_143_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.1996.tb00245.x"},{"key":"e_1_3_1_144_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1977.00500210062011"},{"key":"e_1_3_1_145_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-198708000-00037"},{"key":"e_1_3_1_146_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)81213-X"},{"key":"e_1_3_1_147_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/162.2.474"},{"key":"e_1_3_1_148_2","doi-asserted-by":"publisher","DOI":"10.1086\/514124"},{"key":"e_1_3_1_149_2","doi-asserted-by":"publisher","DOI":"10.1309\/3489075U03LMK9AE"},{"key":"e_1_3_1_150_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M301028200"},{"key":"e_1_3_1_151_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M410176200"},{"key":"e_1_3_1_152_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI36759"},{"key":"e_1_3_1_153_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0046233"},{"key":"e_1_3_1_154_2","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20070004"},{"key":"e_1_3_1_155_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2006.00779.x"},{"key":"e_1_3_1_156_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000911"},{"key":"e_1_3_1_157_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.7.4404-4409.2005"},{"key":"e_1_3_1_158_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002082"},{"key":"e_1_3_1_159_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-12-7"},{"key":"e_1_3_1_160_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2007.02.015"},{"key":"e_1_3_1_161_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600750"},{"key":"e_1_3_1_162_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.8.4556-4563.2002"},{"key":"e_1_3_1_163_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.4.1680-1688.2003"},{"key":"e_1_3_1_164_2","doi-asserted-by":"publisher","DOI":"10.1006\/mpat.2000.0406"},{"key":"e_1_3_1_165_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.67.11.5775-5783.1999"},{"key":"e_1_3_1_166_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1462-5822.2003.t01-1-00271.x"},{"key":"e_1_3_1_167_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.11.6423-6430.2000"},{"key":"e_1_3_1_168_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M007382200"},{"key":"e_1_3_1_169_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2009.10.090"},{"key":"e_1_3_1_170_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110740200"},{"key":"e_1_3_1_171_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M208830200"},{"key":"e_1_3_1_172_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112224200"},{"key":"e_1_3_1_173_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0882-4010(03)00090-1"},{"key":"e_1_3_1_174_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiq009"},{"key":"e_1_3_1_175_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00034-10"},{"key":"e_1_3_1_176_2","doi-asserted-by":"publisher","DOI":"10.1086\/322986"},{"key":"e_1_3_1_177_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00624-10"},{"key":"e_1_3_1_178_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00336-10"},{"key":"e_1_3_1_179_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.06320-11"},{"key":"e_1_3_1_180_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1211915"},{"key":"e_1_3_1_181_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1997.4841857.x"},{"key":"e_1_3_1_182_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2005.04600.x"},{"key":"e_1_3_1_183_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003377"},{"key":"e_1_3_1_184_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1991.tb00807.x"},{"key":"e_1_3_1_185_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1993.tb00922.x"},{"key":"e_1_3_1_186_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2006.06.006"},{"key":"e_1_3_1_187_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.115.6.1231"},{"key":"e_1_3_1_188_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.11.035"},{"key":"e_1_3_1_189_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200106148"},{"key":"e_1_3_1_190_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1999.01459.x"},{"key":"e_1_3_1_191_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.02514"},{"key":"e_1_3_1_192_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2002.03222.x"},{"key":"e_1_3_1_193_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2004.00422.x"},{"key":"e_1_3_1_194_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI2406"},{"key":"e_1_3_1_195_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2010.01490.x"},{"key":"e_1_3_1_196_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20090386"},{"key":"e_1_3_1_197_2","doi-asserted-by":"publisher","DOI":"10.1038\/377435a0"},{"key":"e_1_3_1_198_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.12.7827-7835.2005"},{"key":"e_1_3_1_199_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20092594"},{"key":"e_1_3_1_200_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01559-13"},{"key":"e_1_3_1_201_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.513358"},{"key":"e_1_3_1_202_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002947"},{"key":"e_1_3_1_203_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.65.12.5074-5081.1997"},{"key":"e_1_3_1_204_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01216-08"},{"key":"e_1_3_1_205_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2006.07.003"},{"key":"e_1_3_1_206_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2006.04.130"},{"key":"e_1_3_1_207_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.05506-11"},{"key":"e_1_3_1_208_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.2.637-643.2000"},{"key":"e_1_3_1_209_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.3.1441-1449.2004"},{"key":"e_1_3_1_210_2","first-page":"81","article-title":"Characterization of the invasion of porcine endothelial cells by Streptococcus suis serotype 2","volume":"71","author":"Vanier G","year":"2007","unstructured":"Vanier G Segura M Gottschalk M . 2007. Characterization of the invasion of porcine endothelial cells by Streptococcus suis serotype 2. Can. J. Vet. Res. 71:81\u201389.","journal-title":"Can. J. Vet. Res."},{"key":"e_1_3_1_211_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2008.10.003"},{"key":"e_1_3_1_212_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2008.01255.x"},{"key":"e_1_3_1_213_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.63.11.4268-4276.1995"},{"key":"e_1_3_1_214_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.66.11.5260-5267.1998"},{"key":"e_1_3_1_215_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1998.00776.x"},{"key":"e_1_3_1_216_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.6.3275-3279.2000"},{"key":"e_1_3_1_217_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit250"},{"key":"e_1_3_1_218_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01262-05"},{"key":"e_1_3_1_219_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2002.03190.x"},{"key":"e_1_3_1_220_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00203-008-0413-3"},{"key":"e_1_3_1_221_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.187.18.6556-6560.2005"},{"key":"e_1_3_1_222_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.185.16.4992-4996.2003"},{"key":"e_1_3_1_223_2","doi-asserted-by":"publisher","DOI":"10.4161\/auto.6246"},{"key":"e_1_3_1_224_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2004.04528.x"},{"key":"e_1_3_1_225_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01455-10"},{"key":"e_1_3_1_226_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0063394"},{"key":"e_1_3_1_227_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1107183108"},{"key":"e_1_3_1_228_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01367-13"},{"key":"e_1_3_1_229_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00368-08"},{"key":"e_1_3_1_230_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0091682"},{"key":"e_1_3_1_231_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.1997.tb12768.x"},{"key":"e_1_3_1_232_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.1.95-100.2003"},{"key":"e_1_3_1_233_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2012.12.005"},{"key":"e_1_3_1_234_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.2007\/015172-0"},{"key":"e_1_3_1_235_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2005.03.023"},{"key":"e_1_3_1_236_2","doi-asserted-by":"publisher","DOI":"10.1086\/592447"},{"key":"e_1_3_1_237_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI112407"},{"key":"e_1_3_1_238_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2009.01379.x"},{"key":"e_1_3_1_239_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2012.01805.x"},{"key":"e_1_3_1_240_2","doi-asserted-by":"publisher","DOI":"10.1086\/379042"},{"key":"e_1_3_1_241_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2011.04.025"},{"key":"e_1_3_1_242_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2012.07.063"},{"key":"e_1_3_1_243_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002632"},{"key":"e_1_3_1_244_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055812"},{"key":"e_1_3_1_245_2","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwt013"},{"key":"e_1_3_1_246_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0070020"},{"key":"e_1_3_1_247_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI113736"},{"key":"e_1_3_1_248_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.57.8.2559-2562.1989"},{"key":"e_1_3_1_249_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02630996"},{"key":"e_1_3_1_250_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.63.10.3835-3839.1995"},{"key":"e_1_3_1_251_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.62.9.3739-3744.1994"},{"key":"e_1_3_1_252_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/170.1.254-a"},{"key":"e_1_3_1_253_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/165-Supplement_1-S82"},{"key":"e_1_3_1_254_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1173196"},{"key":"e_1_3_1_255_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.05837-11"},{"key":"e_1_3_1_256_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000874"},{"key":"e_1_3_1_257_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200317335"},{"key":"e_1_3_1_258_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2008.11.004"},{"key":"e_1_3_1_259_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2003.tb00648.x"},{"key":"e_1_3_1_260_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2010.10.035"},{"key":"e_1_3_1_261_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-011-0514-2"},{"key":"e_1_3_1_262_2","first-page":"H286","article-title":"Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines","volume":"273","author":"Blum MS","year":"1997","unstructured":"Blum MS Toninelli E Anderson JM Balda MS Zhou J O'Donnell L Pardi R Bender JR . 1997. Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines. Am. J. Physiol. 273:H286\u2013H294.","journal-title":"Am. J. Physiol."},{"key":"e_1_3_1_263_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1103460"},{"key":"e_1_3_1_264_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-2094-8-28"},{"key":"e_1_3_1_265_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2009.01.019"},{"key":"e_1_3_1_266_2","doi-asserted-by":"publisher","DOI":"10.1006\/jsre.2002.6415"},{"key":"e_1_3_1_267_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00371.2011"},{"key":"e_1_3_1_268_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2014.03.002"},{"key":"e_1_3_1_269_2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/272148"},{"key":"e_1_3_1_270_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.1.606-610.2004"},{"key":"e_1_3_1_271_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2007.06.001"},{"key":"e_1_3_1_272_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.4.2416-2419.2004"},{"key":"e_1_3_1_273_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2001.02448.x"},{"key":"e_1_3_1_274_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01261-07"},{"key":"e_1_3_1_275_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.femsle.2005.08.044"},{"key":"e_1_3_1_276_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0063244"},{"key":"e_1_3_1_277_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00184-08"},{"key":"e_1_3_1_278_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/166.6.1329"},{"key":"e_1_3_1_279_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01966-06"},{"key":"e_1_3_1_280_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.67.7.3512-3517.1999"},{"key":"e_1_3_1_281_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002363"},{"key":"e_1_3_1_282_2","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1079\/9781780641621.0153","volume-title":"Meningitis: cellular and molecular basis","author":"Thwaites G","year":"2013","unstructured":"Thwaites G . 2013. The pathophysiology of tuberculosis meningitis, p 153\u2013167. In Christodoulides M (ed), Meningitis: cellular and molecular basis, vol 26. CAB International, Wallingford, Oxfordshire, United Kingdom."},{"key":"e_1_3_1_283_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.3.1344-1350.2001"},{"key":"e_1_3_1_284_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.7.4418"},{"key":"e_1_3_1_285_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2004.00444.x"},{"key":"e_1_3_1_286_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90418-X"},{"key":"e_1_3_1_287_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1282-11.2011"},{"key":"e_1_3_1_288_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0909032107"},{"key":"e_1_3_1_289_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00418-008-0441-8"},{"key":"e_1_3_1_290_2","first-page":"93","volume-title":"Handbook of olfaction and gustation","author":"Mackay-Sim A","year":"2003","unstructured":"Mackay-Sim A . 2003. Neurogenesis in the adult olfactory neuroepithelium, p 93\u2013113. In Doty RL (ed), Handbook of olfaction and gustation. Dekker, New York, NY."},{"key":"e_1_3_1_291_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.11-04-00979.1991"},{"key":"e_1_3_1_292_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2010.08.008"},{"key":"e_1_3_1_293_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2010.08.025"},{"key":"e_1_3_1_294_2","doi-asserted-by":"publisher","DOI":"10.1038\/35093026"},{"key":"e_1_3_1_295_2","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511543623.003"},{"key":"e_1_3_1_296_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0053462"},{"key":"e_1_3_1_297_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.06828-11"},{"key":"e_1_3_1_298_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep00736"},{"key":"e_1_3_1_299_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2012.05.019"},{"key":"e_1_3_1_300_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.03894.x"},{"key":"e_1_3_1_301_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902940212"},{"key":"e_1_3_1_302_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.10143"},{"key":"e_1_3_1_303_2","first-page":"73","volume-title":"The neurobiology of taste and smell","author":"Bryant BP","year":"2000","unstructured":"Bryant BP Silver WL . 2000. Chemesthesis: the common chemical sense, p 73\u2013100. In Finger TE Silver WL Restrepo D (ed), The neurobiology of taste and smell, 2nd ed. Wiley, New York, NY.","edition":"2"},{"key":"e_1_3_1_304_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1531172100"},{"key":"e_1_3_1_305_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0911934107"},{"key":"e_1_3_1_306_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3181ef241d"},{"key":"e_1_3_1_307_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0010598"},{"key":"e_1_3_1_308_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00129-10"},{"key":"e_1_3_1_309_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0463.2000.d01-13.x"},{"key":"e_1_3_1_310_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiac.2013.10.007"},{"key":"e_1_3_1_311_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0017035"},{"key":"e_1_3_1_312_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1223012"},{"key":"e_1_3_1_313_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature12807"},{"key":"e_1_3_1_314_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI64896"},{"key":"e_1_3_1_315_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.030635-0"},{"key":"e_1_3_1_316_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0063945"},{"key":"e_1_3_1_317_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01146198"},{"key":"e_1_3_1_318_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.334375"},{"key":"e_1_3_1_319_2","doi-asserted-by":"publisher","DOI":"10.4161\/tisb.24997"},{"key":"e_1_3_1_320_2","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2006-0234OC"},{"key":"e_1_3_1_321_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1113219109"},{"key":"e_1_3_1_322_2","doi-asserted-by":"publisher","DOI":"10.1086\/520934"},{"key":"e_1_3_1_323_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.11.7107-7112.2005"},{"key":"e_1_3_1_324_2","doi-asserted-by":"publisher","DOI":"10.1186\/1465-9921-15-21"},{"key":"e_1_3_1_325_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0014034"},{"key":"e_1_3_1_326_2","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20899"},{"key":"e_1_3_1_327_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00025-14"},{"key":"e_1_3_1_328_2","doi-asserted-by":"publisher","DOI":"10.1186\/1742-2094-9-109"},{"key":"e_1_3_1_329_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1402251111"},{"key":"e_1_3_1_330_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.65.2.303"},{"key":"e_1_3_1_331_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2235844100"},{"key":"e_1_3_1_332_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.10.6945-6951.2005"},{"key":"e_1_3_1_333_2","doi-asserted-by":"crossref","first-page":"1875","DOI":"10.4049\/jimmunol.124.4.1875","article-title":"Mapping of the X-linked immune deficiency mutation (xid) of CBA\/N mice","volume":"124","author":"Berning AK","year":"1980","unstructured":"Berning AK Eicher EM Paul WE Scher I . 1980. Mapping of the X-linked immune deficiency mutation (xid) of CBA\/N mice. J. Immunol. 124:1875\u20131877.","journal-title":"J. Immunol."},{"key":"e_1_3_1_334_2","doi-asserted-by":"publisher","DOI":"10.1006\/mpat.1996.0057"},{"key":"e_1_3_1_335_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neures.2010.12.015"},{"key":"e_1_3_1_336_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61016-2"},{"key":"e_1_3_1_337_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1217420110"},{"key":"e_1_3_1_338_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.320.5884.1710"},{"key":"e_1_3_1_339_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2003.99.2.0362"},{"key":"e_1_3_1_340_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1986.64.3.0466"},{"key":"e_1_3_1_341_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2005.73.1162"},{"key":"e_1_3_1_342_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3639.2009.00292.x"},{"key":"e_1_3_1_343_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3639.2005.tb00519.x"},{"key":"e_1_3_1_344_2","doi-asserted-by":"publisher","DOI":"10.1177\/030098587701400401"},{"key":"e_1_3_1_345_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.2.1093-1100.2001"},{"key":"e_1_3_1_346_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.2011.01183.x"},{"key":"e_1_3_1_347_2","first-page":"125","article-title":"Observation on the presence of Listeria monocytogenes in axons","volume":"36","author":"Otter A","year":"1989","unstructured":"Otter A Blakemore WF . 1989. Observation on the presence of Listeria monocytogenes in axons. Acta Microbiol. Hung. 36:125\u2013131.","journal-title":"Acta Microbiol. Hung."},{"key":"e_1_3_1_348_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.8.4682-4686.2002"},{"key":"e_1_3_1_349_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.66.9.4461-4468.1998"},{"key":"e_1_3_1_350_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0300-9475.2004.01500.x"},{"key":"e_1_3_1_351_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01748-13"},{"key":"e_1_3_1_352_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002986"},{"key":"e_1_3_1_353_2","doi-asserted-by":"publisher","DOI":"10.3109\/13550284.2010.489596"},{"key":"e_1_3_1_354_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.8.3839-3851.2002"},{"key":"e_1_3_1_355_2","doi-asserted-by":"publisher","DOI":"10.3109\/13550280009030756"},{"key":"e_1_3_1_356_2","doi-asserted-by":"publisher","DOI":"10.3109\/13550289909045376"},{"key":"e_1_3_1_357_2","doi-asserted-by":"publisher","DOI":"10.1053\/jcpa.2000.0461"},{"key":"e_1_3_1_358_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.9.4806-4816.2004"},{"key":"e_1_3_1_359_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1105143108"},{"key":"e_1_3_1_360_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(82)90183-6"},{"key":"e_1_3_1_361_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0083603"},{"key":"e_1_3_1_362_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2012.08.005"},{"key":"e_1_3_1_363_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-004-0909-0"},{"key":"e_1_3_1_364_2","doi-asserted-by":"publisher","DOI":"10.1089\/088282403322396208"},{"key":"e_1_3_1_365_2","doi-asserted-by":"publisher","DOI":"10.1080\/13550280701427069"},{"key":"e_1_3_1_366_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00239-11"},{"key":"e_1_3_1_367_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-012-1010-8"},{"key":"e_1_3_1_368_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0046605"},{"key":"e_1_3_1_369_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-83-9-2109"},{"key":"e_1_3_1_370_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2009.03.016"},{"key":"e_1_3_1_371_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.03509-13"},{"key":"e_1_3_1_372_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiu097"},{"key":"e_1_3_1_373_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00697190"},{"key":"e_1_3_1_374_2","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-76-5-1251"},{"key":"e_1_3_1_375_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.1987.tb00175.x"},{"key":"e_1_3_1_376_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.12.7528-7534.2005"},{"key":"e_1_3_1_377_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0040308"},{"key":"e_1_3_1_378_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64493-8"},{"key":"e_1_3_1_379_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1995.1197"},{"key":"e_1_3_1_380_2","doi-asserted-by":"publisher","DOI":"10.1186\/1743-422X-6-170"},{"key":"e_1_3_1_381_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.05032-11"},{"key":"e_1_3_1_382_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.27.1.67"},{"key":"e_1_3_1_383_2","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(91)90145-2"},{"key":"e_1_3_1_384_2","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(88)90397-1"},{"key":"e_1_3_1_385_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.72.9.7181-7190.1998"},{"key":"e_1_3_1_386_2","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1995.1252"},{"key":"e_1_3_1_387_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis626"},{"key":"e_1_3_1_388_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1702.100442"},{"key":"e_1_3_1_389_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700960102"},{"key":"e_1_3_1_390_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196912112812401"},{"key":"e_1_3_1_391_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-004-1177-6"},{"key":"e_1_3_1_392_2","doi-asserted-by":"publisher","DOI":"10.1645\/0022-3395(2000)086[0050:ALMSOT]2.0.CO;2"},{"key":"e_1_3_1_393_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.2008\/019380-0"},{"key":"e_1_3_1_394_2","first-page":"545","article-title":"Animal model of human disease. Primary amebic meningoencephalitis, Naegleria meningoencephalitis, CNS protozoal infection","volume":"73","author":"Martinez AJ","year":"1973","unstructured":"Martinez AJ Nelson EC Duma RJ . 1973. Animal model of human disease. Primary amebic meningoencephalitis, Naegleria meningoencephalitis, CNS protozoal infection. Am. J. Pathol. 73:545\u2013548.","journal-title":"Am. J. Pathol."},{"key":"e_1_3_1_395_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.063255-0"},{"key":"e_1_3_1_396_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-004-1163-z"},{"key":"e_1_3_1_397_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-012-0266-4"},{"key":"e_1_3_1_398_2","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.12.102"},{"key":"e_1_3_1_399_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00437444"},{"key":"e_1_3_1_400_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00467683"},{"key":"e_1_3_1_401_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00437432"},{"key":"e_1_3_1_402_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1006809522931"},{"key":"e_1_3_1_403_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(94)90223-2"},{"key":"e_1_3_1_404_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.160.1.3715034"},{"key":"e_1_3_1_405_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410280121"},{"key":"e_1_3_1_406_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-198909000-00023"},{"key":"e_1_3_1_407_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-198809010-00005"},{"key":"e_1_3_1_408_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2004.07.015"},{"key":"e_1_3_1_409_2","first-page":"114","article-title":"Perineural spread of rhinocerebral mucormycosis","volume":"17","author":"McLean FM","year":"1996","unstructured":"McLean FM Ginsberg LE Stanton CA . 1996. Perineural spread of rhinocerebral mucormycosis. Am. J. Neuroradiol. 17:114\u2013116.","journal-title":"Am. J. Neuroradiol."},{"key":"e_1_3_1_410_2","doi-asserted-by":"publisher","DOI":"10.5858\/2001-125-0375-HFOZ"},{"key":"e_1_3_1_411_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.5.2923-2931.2005"},{"key":"e_1_3_1_412_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2006.10.091"},{"key":"e_1_3_1_413_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00430-006-0034-x"},{"key":"e_1_3_1_414_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0035862"},{"key":"e_1_3_1_415_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.67.3.1131-1138.1999"},{"key":"e_1_3_1_416_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.63.11.4470-4475.1995"},{"key":"e_1_3_1_417_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.9.5062-5067.2000"},{"key":"e_1_3_1_418_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.9.5056-5061.2000"},{"key":"e_1_3_1_419_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.67.9.4751-4756.1999"},{"key":"e_1_3_1_420_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01543-06"},{"key":"e_1_3_1_421_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2000.01952.x"},{"key":"e_1_3_1_422_2","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/19.7.1458"},{"key":"e_1_3_1_423_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)00141-0"},{"key":"e_1_3_1_424_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-010-0630-5"},{"key":"e_1_3_1_425_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI23829"},{"key":"e_1_3_1_426_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01153-06"},{"key":"e_1_3_1_427_2","doi-asserted-by":"publisher","DOI":"10.1086\/598217"},{"key":"e_1_3_1_428_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M402164200"},{"key":"e_1_3_1_429_2","doi-asserted-by":"publisher","DOI":"10.1080\/13550280590922793"},{"key":"e_1_3_1_430_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2011.01.008"},{"key":"e_1_3_1_431_2","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20586"}],"container-title":["Clinical Microbiology Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/CMR.00118-13","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/CMR.00118-13","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,16]],"date-time":"2023-07-16T20:13:55Z","timestamp":1689538435000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/CMR.00118-13"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10]]},"references-count":430,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["10.1128\/CMR.00118-13"],"URL":"https:\/\/doi.org\/10.1128\/cmr.00118-13","relation":{},"ISSN":["0893-8512","1098-6618"],"issn-type":[{"value":"0893-8512","type":"print"},{"value":"1098-6618","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10]]},"assertion":[{"value":"2014-10-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}