{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T13:30:16Z","timestamp":1789047016715,"version":"build-2803163510"},"reference-count":199,"publisher":"American Society for Microbiology","issue":"3","license":[{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Microbiol Rev"],"published-print":{"date-parts":[[2026,9,10]]},"abstract":"<jats:title>SUMMARY<\/jats:title>\n                  <jats:p>\n                    <jats:italic toggle=\"yes\">Streptococcus suis<\/jats:italic>\n                    is a swine pathogen causing significant economic losses and an important zoonotic agent in humans. Southeast Asia is a high-incidence region, where infection is strongly linked to consumption of raw or undercooked pork and occupational exposure to pigs or pork products. Thailand and Vietnam report the highest case numbers, with additional cases in Indonesia (Bali), Malaysia, Singapore, Lao PDR, and Cambodia. Serotype 2 predominates in both humans and pigs, followed by serotype 14, while other serotypes (1, 4, 5, 7, 9, 16, 24, and 31) are also reported in humans. In pigs, a broader serotype range is observed, including 1 or 14, 2, 4, 5, 6, 7, 8, 9, 15, 16, 18, 21, 29, 31, and nontypeable strains. Human infections involve multiple clonal complexes (CC1, CC16, CC25, CC28, CC94, CC104, CC233, CC221\/234, and CC1688), several overlapping with porcine lineages. The region is also challenged by increasing antimicrobial resistance, with rising non-susceptibility to macrolides and tetracyclines and occasional reduced susceptibility to penicillin. Diagnostic limitations due to misidentification, limited molecular tools, and reliance on conventional methods further complicate surveillance. The economic burden is substantial, driven by swine losses, treatment costs, outbreaks, and severe human disease. Vaccination remains suboptimal due to limited protection against genetically and antigenically diverse strains across serotypes and CCs. An urgent One Health approach integrating animal health, food safety, and human health is needed to monitor\n                    <jats:italic toggle=\"yes\">S. suis<\/jats:italic>\n                    dynamics. Control measures should target farms, slaughterhouses, and retail markets while promoting community-accepted behavioral changes to reduce transmission risk.\n                  <\/jats:p>","DOI":"10.1128\/cmr.00133-25","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T12:46:55Z","timestamp":1786452415000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["<i>Streptococcus suis<\/i>\n                    disease in Southeast Asia: microbiology and epidemiology in humans and pigs"],"prefix":"10.1128","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1055-3656","authenticated-orcid":true,"given":"Anusak","family":"Kerdsin","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05gzceg21","id-type":"ROR","asserted-by":"publisher"}],"name":"Faculty of Public Health, Kasetsart University, Chalermphrakiat Sakon Nakhon Province Campus","place":["Sakon Nakhon, Thailand"]},{"id":[{"id":"https:\/\/ror.org\/028wp3y58","id-type":"ROR","asserted-by":"publisher"}],"name":"Faculty of Veterinary Science, Chulalongkorn University","place":["Bangkok, Thailand"]},{"id":[{"id":"https:\/\/ror.org\/028wp3y58","id-type":"ROR","asserted-by":"publisher"}],"name":"Center of Excellence for Food and Water Risk Analysis (FAWRA), Department of Veterinary Public Health, Faculty of Veterinary Science, Chulalongkorn University","place":["Bangkok, Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suphachai","family":"Nuanuansuwan","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/05gzceg21","id-type":"ROR","asserted-by":"publisher"}],"name":"Faculty of Public Health, Kasetsart University, Chalermphrakiat Sakon Nakhon Province Campus","place":["Sakon Nakhon, Thailand"]},{"id":[{"id":"https:\/\/ror.org\/028wp3y58","id-type":"ROR","asserted-by":"publisher"}],"name":"Faculty of Veterinary Science, Chulalongkorn University","place":["Bangkok, Thailand"]},{"id":[{"id":"https:\/\/ror.org\/028wp3y58","id-type":"ROR","asserted-by":"publisher"}],"name":"Center of Excellence for Food and Water Risk Analysis (FAWRA), Department of Veterinary Public Health, Faculty of Veterinary Science, Chulalongkorn University","place":["Bangkok, Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rattagan","family":"Kajeekul","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0152ray34","id-type":"ROR","asserted-by":"publisher"}],"name":"Department of Medicine, Maharat Nakhon Ratchasima Hospital","place":["Nakhon Ratchasima, Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9553-3798","authenticated-orcid":true,"given":"Nahuel","family":"Fittipaldi","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/028wp3y58","id-type":"ROR","asserted-by":"publisher"}],"name":"Faculty of Veterinary Science, Chulalongkorn University","place":["Bangkok, Thailand"]},{"id":[{"id":"https:\/\/ror.org\/0161xgx34","id-type":"ROR","asserted-by":"publisher"}],"name":"Groupe de recherche sur les maladies infectieuses en production animale, and Centre de recherche en infectiologie porcine et avicole, Facult\u00e9 de m\u00e9decine v\u00e9t\u00e9rinaire, Universit\u00e9 de Montr\u00e9al","place":["St-Hyacinthe, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7489-4882","authenticated-orcid":true,"given":"Mariela","family":"Segura","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/028wp3y58","id-type":"ROR","asserted-by":"publisher"}],"name":"Faculty of Veterinary Science, Chulalongkorn University","place":["Bangkok, Thailand"]},{"id":[{"id":"https:\/\/ror.org\/0161xgx34","id-type":"ROR","asserted-by":"publisher"}],"name":"Groupe de recherche sur les maladies infectieuses en production animale, and Centre de recherche en infectiologie porcine et avicole, Facult\u00e9 de m\u00e9decine v\u00e9t\u00e9rinaire, Universit\u00e9 de Montr\u00e9al","place":["St-Hyacinthe, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2196-2212","authenticated-orcid":true,"given":"Marcelo","family":"Gottschalk","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/028wp3y58","id-type":"ROR","asserted-by":"publisher"}],"name":"Faculty of Veterinary Science, Chulalongkorn University","place":["Bangkok, Thailand"]},{"id":[{"id":"https:\/\/ror.org\/0161xgx34","id-type":"ROR","asserted-by":"publisher"}],"name":"Groupe de recherche sur les maladies infectieuses en production animale, and Centre de recherche en infectiologie porcine et avicole, Facult\u00e9 de m\u00e9decine v\u00e9t\u00e9rinaire, Universit\u00e9 de Montr\u00e9al","place":["St-Hyacinthe, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/emi.2014.45"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2007.131594"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid3003.230348"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid3107.241835"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/foods11091190"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-85679-3_2"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1086\/596763"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/2049-9957-4-11"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-37-2-160"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens5030045"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-48-2-581"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.67.10.4828-4833.2001"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2005.01.003"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2012.11.001"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.067116-0"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1099\/ijsem.0.002204"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.31.8.2192-2194.1993"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.10.3146-3152.1999"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.8.2922-2929.2002"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2005.12.013"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01584-12"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0072070"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03411-13"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.069757-0"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2015.07.018"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.001950"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-016-0782-8"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1177\/1040638720915869"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00480-20"},{"key":"e_1_3_4_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2023.106828"},{"key":"e_1_3_4_32_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-024-04361-9"},{"key":"e_1_3_4_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02962-14"},{"key":"e_1_3_4_34_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02102-16"},{"key":"e_1_3_4_35_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13567-017-0417-6"},{"key":"e_1_3_4_36_2","doi-asserted-by":"publisher","DOI":"10.1111\/tbed.13123"},{"key":"e_1_3_4_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2019.108534"},{"key":"e_1_3_4_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2024.110265"},{"key":"e_1_3_4_39_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13567-024-01366-y"},{"key":"e_1_3_4_40_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2307773120"},{"key":"e_1_3_4_41_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2015.01191"},{"key":"e_1_3_4_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2025.105753"},{"key":"e_1_3_4_43_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.01030-25"},{"key":"e_1_3_4_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1135(86)90065-9"},{"key":"e_1_3_4_45_2","doi-asserted-by":"publisher","DOI":"10.1177\/104063879000200324"},{"key":"e_1_3_4_46_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.32.2.578-580.1994"},{"key":"e_1_3_4_47_2","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.10.2"},{"key":"e_1_3_4_48_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2015.00202"},{"key":"e_1_3_4_49_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01297-21"},{"key":"e_1_3_4_50_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.00374-24"},{"key":"e_1_3_4_51_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6968.2003.tb11501.x"},{"key":"e_1_3_4_52_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.7.3169-3175.2004"},{"key":"e_1_3_4_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mimet.2014.09.003"},{"key":"e_1_3_4_54_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-022-08710-6"},{"key":"e_1_3_4_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2010.04.002"},{"key":"e_1_3_4_56_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.10.3671-3680.2002"},{"key":"e_1_3_4_57_2","doi-asserted-by":"publisher","DOI":"10.12688\/wellcomeopenres.14826.1"},{"key":"e_1_3_4_58_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0033854"},{"key":"e_1_3_4_59_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00377-19"},{"key":"e_1_3_4_60_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13567-020-00813-w"},{"key":"e_1_3_4_61_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e27818"},{"key":"e_1_3_4_62_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-025-05225-2"},{"key":"e_1_3_4_63_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2312.171005"},{"key":"e_1_3_4_64_2","doi-asserted-by":"publisher","DOI":"10.1086\/527385"},{"key":"e_1_3_4_65_2","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000952"},{"key":"e_1_3_4_66_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2015.06.011"},{"key":"e_1_3_4_67_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-018-3208-8"},{"key":"e_1_3_4_68_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.812436"},{"key":"e_1_3_4_69_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-024-05029-w"},{"key":"e_1_3_4_70_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0288840"},{"key":"e_1_3_4_71_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13567-025-01562-4"},{"key":"e_1_3_4_72_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1705.100754"},{"key":"e_1_3_4_73_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-32724-z"},{"key":"e_1_3_4_74_2","doi-asserted-by":"publisher","DOI":"10.3390\/tropicalmed7110359"},{"key":"e_1_3_4_75_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1401.070534"},{"key":"e_1_3_4_76_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2512.181709"},{"key":"e_1_3_4_77_2","doi-asserted-by":"publisher","DOI":"10.3889\/oamjms.2020.3255"},{"key":"e_1_3_4_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(14)70289-X"},{"key":"e_1_3_4_79_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0059775"},{"key":"e_1_3_4_80_2","unstructured":"Vlieghe E. 2014. The microbiological spectrum of invasive bacterial infections in Cambodian adults and implications for standard treatment guidelines. Master\u2019s thesis University of Leuven Belgium."},{"key":"e_1_3_4_81_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1401.070930"},{"key":"e_1_3_4_82_2","doi-asserted-by":"publisher","DOI":"10.3390\/ani13040625"},{"key":"e_1_3_4_83_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1968.tb03456.x"},{"key":"e_1_3_4_84_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2008.tb02100.x"},{"key":"e_1_3_4_85_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-016-2006-0"},{"key":"e_1_3_4_86_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2402.171138"},{"key":"e_1_3_4_87_2","first-page":"632","article-title":"Adult community acquired bacterial meningitis in a Singaporean teaching hospital. A seven-year overview (1993-2000)","volume":"43","author":"Chan YC","year":"2002","unstructured":"Chan YC, Wilder-Smith A, Ong BKC, Kumarasinghe G, Wilder-Smith E. 2002. Adult community acquired bacterial meningitis in a Singaporean teaching hospital. A seven-year overview (1993-2000). Singapore Med J 43:632\u2013636.","journal-title":"Singapore Med J"},{"key":"e_1_3_4_88_2","first-page":"e30","article-title":"Deafness due to haemorrhagic labyrinthitis and a review of relapses in Streptococcus suis meningitis","volume":"51","author":"Tan JH","year":"2010","unstructured":"Tan JH, Yeh BI, Seet CS. 2010. Deafness due to haemorrhagic labyrinthitis and a review of relapses in Streptococcus suis meningitis. Singap Med J 51:e30\u2013e33.","journal-title":"Singap Med J"},{"key":"e_1_3_4_89_2","first-page":"178","article-title":"Streptococcus suis infection: overview of case reports in Thailand","volume":"34","author":"Teekakirikul P","year":"2003","unstructured":"Teekakirikul P, Wiwanitkit V. 2003. Streptococcus suis infection: overview of case reports in Thailand. Southeast Asian J Trop Med Public Health 34:178\u2013183.","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"e_1_3_4_90_2","first-page":"511","article-title":"Streptococcus suis infection: a prospective study in northern Thailand","volume":"40","author":"Fongcom A","year":"2009","unstructured":"Fongcom A, Pruksakorn S, Netsirisawan P, Pongprasert R, Onsibud P. 2009. Streptococcus suis infection: a prospective study in northern Thailand. Southeast Asian J Trop Med Public Health 40:511\u2013517.","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"e_1_3_4_91_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-017-2294-z"},{"key":"e_1_3_4_92_2","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12260"},{"key":"e_1_3_4_93_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10393-022-01611-w"},{"key":"e_1_3_4_94_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.23-0774"},{"key":"e_1_3_4_95_2","doi-asserted-by":"publisher","DOI":"10.1093\/trstmh\/trz004"},{"key":"e_1_3_4_96_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0037825"},{"key":"e_1_3_4_97_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0042099"},{"key":"e_1_3_4_98_2","doi-asserted-by":"publisher","DOI":"10.1186\/s41182-021-00322-2"},{"key":"e_1_3_4_99_2","doi-asserted-by":"publisher","DOI":"10.7883\/yoken.JJID.2021.789"},{"key":"e_1_3_4_100_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-23007-0"},{"key":"e_1_3_4_101_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-017-2582-7"},{"key":"e_1_3_4_102_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268815000990"},{"key":"e_1_3_4_103_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-023-08300-1"},{"key":"e_1_3_4_104_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0031265"},{"key":"e_1_3_4_105_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2102.140961"},{"key":"e_1_3_4_106_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0013110"},{"key":"e_1_3_4_107_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgph.0003995"},{"key":"e_1_3_4_108_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-024-10180-y"},{"key":"e_1_3_4_109_2","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-025-02497-w"},{"key":"e_1_3_4_110_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-96609-z"},{"key":"e_1_3_4_111_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.onehlt.2022.100394"},{"key":"e_1_3_4_112_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.radcr.2022.08.030"},{"key":"e_1_3_4_113_2","first-page":"23","article-title":"Meningitis caused by Streptococcus suis","volume":"8","author":"Oeng S","year":"2021","unstructured":"Oeng S, Sokun L, Tan V, Townell N, Baron E, Letchford J. 2021. Meningitis caused by Streptococcus suis. Case Rep Clin Pathol 8:23\u201326.","journal-title":"Case Rep Clin Pathol"},{"key":"e_1_3_4_114_2","doi-asserted-by":"publisher","DOI":"10.1093\/clind\/24.4.710"},{"key":"e_1_3_4_115_2","unstructured":"Coner-Nobleza MJ Ramos-Jason R Lerios JKG Gregorio KMR. 2016. Streptococcus suis septicemia: a case series from the Philippines. Philippines. Health Research and Development Information Network (HERDIN). https:\/\/www.herdin.ph\/index.php\/partner\/journal?view=research&cid=60597&layout=default_full."},{"key":"e_1_3_4_116_2","first-page":"13","article-title":"Streptococcus suis meningoencephalitis with seizure from raw pork ingestion: a case report","volume":"73","author":"Wongjittraporn S","year":"2014","unstructured":"Wongjittraporn S, Teerasukjinda O, Yee M, Chung HH. 2014. Streptococcus suis meningoencephalitis with seizure from raw pork ingestion: a case report. Hawaii J Med Public Health 73:13\u201314.","journal-title":"Hawaii J Med Public Health"},{"key":"e_1_3_4_117_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0017604"},{"key":"e_1_3_4_118_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.onehlt.2021.100254"},{"key":"e_1_3_4_119_2","doi-asserted-by":"publisher","DOI":"10.14202\/vetworld.2024.1-7"},{"key":"e_1_3_4_120_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-31598-w"},{"key":"e_1_3_4_121_2","unstructured":"Yana A. 2008. Knowledge and practice in prevention of Streptococcus suis infection among people in Mae-Narua sub-district Mueang district Phayao province. Master\u2019s thesis Chiang Mai University Thailand."},{"key":"e_1_3_4_122_2","unstructured":"Kaewmoon P. 2009. Knowledge and practice in prevention of Streptococcus suis infection among people in Tha-It Subdistrict Mueang District Uttaradit Province. Master\u2019s thesis Chiang Mai University Chiang Mai Thailand."},{"key":"e_1_3_4_123_2","doi-asserted-by":"publisher","DOI":"10.3390\/foods11091190"},{"key":"e_1_3_4_124_2","first-page":"5","article-title":"Factors associated with the incidence of Streptococcus suis infection in Nakhon Ratchasima Province: a matched case-control study","volume":"30","author":"Chongkratok P","year":"2024","unstructured":"Chongkratok P, Charerntanyarak L. 2024. Factors associated with the incidence of Streptococcus suis infection in Nakhon Ratchasima Province: a matched case-control study. J Office Dis Prev Control 9 Nakhon Ratchasima 30:5\u201317.","journal-title":"J Office Dis Prev Control 9 Nakhon Ratchasima"},{"key":"e_1_3_4_125_2","unstructured":"Thongsawad S. 2016. Burden and epidemiological characterisations of Streptococcus suis in Chiang Mai Thailand. PhD thesis University of Edinburgh UK. http:\/\/hdl.handle.net\/1842\/29002."},{"key":"e_1_3_4_126_2","first-page":"836","article-title":"The relationship between health literacy and related factors toward Streptococcus suis prevention behaviors among people in Nakhon Sawan Province","volume":"48","author":"Kantee P","year":"2022","unstructured":"Kantee P, Sombhopcharoen M, Therawiwat M. 2022. The relationship between health literacy and related factors toward Streptococcus suis prevention behaviors among people in Nakhon Sawan Province. Dis Control J 48:836\u2013847.","journal-title":"Dis Control J"},{"key":"e_1_3_4_127_2","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S233326"},{"key":"e_1_3_4_128_2","first-page":"45","article-title":"Clinical characteristics and factors associated with mortality of Streptococcus suis infection in Ratchaburi Hospital, Thailand","volume":"40","author":"Dhitinanmuang W","year":"2023","unstructured":"Dhitinanmuang W. 2023. Clinical characteristics and factors associated with mortality of Streptococcus suis infection in Ratchaburi Hospital, Thailand. J Infect Dis Antimicrob Agents 40:45\u201356.","journal-title":"J Infect Dis Antimicrob Agents"},{"key":"e_1_3_4_129_2","doi-asserted-by":"publisher","DOI":"10.1086\/425368"},{"key":"e_1_3_4_130_2","doi-asserted-by":"publisher","DOI":"10.2471\/B09452"},{"key":"e_1_3_4_131_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2008.08.006"},{"key":"e_1_3_4_132_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004191"},{"key":"e_1_3_4_133_2","doi-asserted-by":"publisher","DOI":"10.3343\/kjlm.2011.31.2.115"},{"key":"e_1_3_4_134_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eimce.2021.11.001"},{"key":"e_1_3_4_135_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2018-228501"},{"key":"e_1_3_4_136_2","doi-asserted-by":"publisher","DOI":"10.1097\/ICB.0000000000001261"},{"key":"e_1_3_4_137_2","first-page":"1274","article-title":"Streptococcus suis peritonitis: case report","volume":"83","author":"Vilaichone RK","year":"2000","unstructured":"Vilaichone RK, Mahachai V, Nunthapisud P. 2000. Streptococcus suis peritonitis: case report. J Med Assoc Thai 83:1274\u20131277.","journal-title":"J Med Assoc Thai"},{"key":"e_1_3_4_138_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-026-13332-4"},{"key":"e_1_3_4_139_2","doi-asserted-by":"publisher","DOI":"10.1093\/jacamr\/dlae215"},{"key":"e_1_3_4_140_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2017.09.011"},{"key":"e_1_3_4_141_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehad193"},{"key":"e_1_3_4_142_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0008985"},{"key":"e_1_3_4_143_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-023-15623-w"},{"key":"e_1_3_4_144_2","first-page":"322","article-title":"Streptococcus suis serotype 2 outbreak at Chomthong district, Chiang Mai province, June\u2013July 2008","volume":"6","author":"Wongsawat S","year":"2010","unstructured":"Wongsawat S. 2010. Streptococcus suis serotype 2 outbreak at Chomthong district, Chiang Mai province, June\u2013July 2008. Lanna Public Health J 6:322\u2013336.","journal-title":"Lanna Public Health J"},{"key":"e_1_3_4_145_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2017.09.019"},{"key":"e_1_3_4_146_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0228488"},{"key":"e_1_3_4_147_2","first-page":"654","article-title":"Streptococcus suis meningitis: the newest serious infectious disease","volume":"91","author":"Rusmeechan S","year":"2008","unstructured":"Rusmeechan S, Sribusara P. 2008. Streptococcus suis meningitis: the newest serious infectious disease. J Med Assoc Thai 91:654\u2013658.","journal-title":"J Med Assoc Thai"},{"key":"e_1_3_4_148_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11030410"},{"key":"e_1_3_4_149_2","unstructured":"Wattanaphansak S. 2025. Updated information on Streptococcus suis in diseased pigs in Thailand"},{"key":"e_1_3_4_150_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-019-4826-7"},{"key":"e_1_3_4_151_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13567-021-00918-w"},{"key":"e_1_3_4_152_2","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2022.1048861"},{"key":"e_1_3_4_153_2","doi-asserted-by":"publisher","DOI":"10.1354\/vp.37-2-143"},{"key":"e_1_3_4_154_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid1902.120470"},{"key":"e_1_3_4_155_2","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.14-0380"},{"key":"e_1_3_4_156_2","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens9010050"},{"key":"e_1_3_4_157_2","doi-asserted-by":"publisher","DOI":"10.1155\/2024\/3186518"},{"key":"e_1_3_4_158_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0017943"},{"key":"e_1_3_4_159_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-48406-9"},{"key":"e_1_3_4_160_2","first-page":"8","article-title":"Prevalence of Streptococcus suis in tonsils of slaughtered pigs in Lampang and Phayao provinces, Thailand, 2009\u20132010","volume":"36","author":"Pathanasophon P","year":"2013","unstructured":"Pathanasophon P, Worarach A, Narongsak W, Yuwapanichsampan S, Nuangmek A, Sakdasirisathaporn A, Chuxnum T. 2013. Prevalence of Streptococcus suis in tonsils of slaughtered pigs in Lampang and Phayao provinces, Thailand, 2009\u20132010. J Trop Med Parasitol 36:8\u201314.","journal-title":"J Trop Med Parasitol"},{"key":"e_1_3_4_161_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-016-2354-2"},{"key":"e_1_3_4_162_2","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/350416"},{"key":"e_1_3_4_163_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2013.04.025"},{"key":"e_1_3_4_164_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2406.171271"},{"key":"e_1_3_4_165_2","doi-asserted-by":"publisher","DOI":"10.7589\/2017-11-281"},{"key":"e_1_3_4_166_2","first-page":"43","article-title":"Endocarditis and meningitis caused by Streptococcus suis after cardiac surgery in a sheep","volume":"39","author":"Wilson RP","year":"2000","unstructured":"Wilson RP, Griffith JW. 2000. Endocarditis and meningitis caused by Streptococcus suis after cardiac surgery in a sheep. Contemp Top Lab Anim Sci 39:43\u201346.","journal-title":"Contemp Top Lab Anim Sci"},{"key":"e_1_3_4_167_2","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12711"},{"key":"e_1_3_4_168_2","doi-asserted-by":"publisher","DOI":"10.1177\/20551169211012346"},{"key":"e_1_3_4_169_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2022.739173"},{"key":"e_1_3_4_170_2","doi-asserted-by":"publisher","DOI":"10.47665\/tb.41.1.012"},{"key":"e_1_3_4_171_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12915-025-02477-4"},{"key":"e_1_3_4_172_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro.2017.45"},{"key":"e_1_3_4_173_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms12112191"},{"key":"e_1_3_4_174_2","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000882"},{"key":"e_1_3_4_175_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-11-6"},{"key":"e_1_3_4_176_2","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens10091178"},{"key":"e_1_3_4_177_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-018-1732-5"},{"key":"e_1_3_4_178_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.12.3675-3681.2003"},{"key":"e_1_3_4_179_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2016.00118"},{"key":"e_1_3_4_180_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2011.00235"},{"key":"e_1_3_4_181_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-016-2616-x"},{"key":"e_1_3_4_182_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkf099"},{"key":"e_1_3_4_183_2","doi-asserted-by":"publisher","DOI":"10.7883\/yoken.JJID.2006.397"},{"key":"e_1_3_4_184_2","doi-asserted-by":"publisher","DOI":"10.7883\/yoken.JJID.2016.294"},{"key":"e_1_3_4_185_2","doi-asserted-by":"publisher","DOI":"10.5455\/IJMRCR.172-1666274899"},{"key":"e_1_3_4_186_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics12010158"},{"key":"e_1_3_4_187_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkad395"},{"key":"e_1_3_4_188_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2025.110569"},{"key":"e_1_3_4_189_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2025.107604"},{"key":"e_1_3_4_190_2","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2024.2339946"},{"key":"e_1_3_4_191_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms8091292"},{"key":"e_1_3_4_192_2","first-page":"66","article-title":"Farm characteristics and management practices associated with the detection of Streptococcus suis among smallhold swine farms in the Philippines","volume":"61","author":"Sedano SA","year":"2024","unstructured":"Sedano SA, Tandang NA, Estacio MAC, Cantalejo M, Guzman A, Lapitan C, Silva BBI. 2024. Farm characteristics and management practices associated with the detection of Streptococcus suis among smallhold swine farms in the Philippines. Philipp J Vet Med 61:66\u201377.","journal-title":"Philipp J Vet Med"},{"key":"e_1_3_4_193_2","doi-asserted-by":"publisher","DOI":"10.59796\/jcst.V14N2.2024.70"},{"key":"e_1_3_4_194_2","doi-asserted-by":"publisher","DOI":"10.1111\/zph.13132"},{"key":"e_1_3_4_195_2","first-page":"152","article-title":"Streptococcus suis contamination in raw pork meat, fresh pig blood, visceral organs, fermented pork (Nham-mooh), and raw spicy minced pork salad (Larb) in the upper part of northeastern Thailand","volume":"16","author":"Tongsakulpanis N","year":"2016","unstructured":"Tongsakulpanis N, Direksin K. 2016. Streptococcus suis contamination in raw pork meat, fresh pig blood, visceral organs, fermented pork (Nham-mooh), and raw spicy minced pork salad (Larb) in the upper part of northeastern Thailand. KKU Vet J 16:152\u2013174.","journal-title":"KKU Vet J"},{"key":"e_1_3_4_196_2","doi-asserted-by":"publisher","DOI":"10.14202\/vetworld.2019.165-169"},{"key":"e_1_3_4_197_2","doi-asserted-by":"publisher","DOI":"10.3390\/foods13132119"},{"key":"e_1_3_4_198_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-95480-2"},{"key":"e_1_3_4_199_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2020.107432"},{"key":"e_1_3_4_200_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fm.2016.09.002"}],"container-title":["Clinical Microbiology Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/cmr.00133-25","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/cmr.00133-25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T13:01:54Z","timestamp":1789045314000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/cmr.00133-25"}},"subtitle":[],"editor":[{"given":"Graeme N.","family":"Forrest","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,9,10]]},"references-count":199,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,9,10]]}},"alternative-id":["10.1128\/cmr.00133-25"],"URL":"https:\/\/doi.org\/10.1128\/cmr.00133-25","relation":{},"ISSN":["0893-8512","1098-6618"],"issn-type":[{"value":"0893-8512","type":"print"},{"value":"1098-6618","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,10]]},"assertion":[{"value":"2026-08-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00133-25"}}