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Localized disease is the typical clinical form in immunocompetent patients. Immunocompromised hosts at elevated risk of developing invasive fusariosis are patients with acute leukemia receiving chemotherapeutic regimens for remission induction, and those undergoing allogeneic hematopoietic cell transplant. In this setting, the infection is usually disseminated with positive blood cultures, multiple painful metastatic skin lesions, and lung involvement. Currently available antifungal agents have poor\n            <jats:italic>in vitro<\/jats:italic>\n            activity against\n            <jats:italic>Fusarium<\/jats:italic>\n            species, but a clear-cut correlation between\n            <jats:italic>in vitro<\/jats:italic>\n            activity and clinical effectiveness does not exist. The outcome of invasive fusariosis is largely dependent on the resolution of immunosuppression, especially neutrophil recovery in neutropenic patients.\n          <\/jats:p>","DOI":"10.1128\/cmr.00159-22","type":"journal-article","created":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T14:01:08Z","timestamp":1699452068000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":82,"title":["Invasive fusariosis"],"prefix":"10.1128","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4867-0014","authenticated-orcid":true,"given":"Marcio","family":"Nucci","sequence":"first","affiliation":[{"name":"University Hospital, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil"},{"name":"Grupo Oncocl\u00ednicas, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elias","family":"Anaissie","sequence":"additional","affiliation":[{"name":"CTI Clinical Trial and Consulting, 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