{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T00:04:51Z","timestamp":1793232291206,"version":"4.5.0"},"reference-count":36,"publisher":"American Society for Microbiology","issue":"7","license":[{"start":{"date-parts":[[2006,7,1]],"date-time":"2006-07-01T00:00:00Z","timestamp":1151712000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Vaccine Immunol"],"published-print":{"date-parts":[[2006,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Guillain-Barre\u0301 syndrome (GBS) is a postinfectious autoimmune polyradiculoneuropathy. The most frequent antecedent pathogen is\n            <jats:italic>Campylobacter jejuni<\/jats:italic>\n            , followed by cytomegalovirus. However, more than 40% of GBS cases currently cannot be attributed to triggering events. This might be due to the shortcomings of the serological assays used for diagnosing infections, in particular for\n            <jats:italic>C. jejuni<\/jats:italic>\n            . In our study investigating 36 patients with acute GBS, standard serological methods identified the triggering viral or bacterial etiology in only 25% of cases. However, using a highly specific enzyme-linked immunosorbent assay based on two recombinant outer antigens encoded by\n            <jats:italic>C. jejuni<\/jats:italic>\n            genes Cj0017 (P39) and Cj0113 (P18), we found serological evidence of a preceding\n            <jats:italic>C. jejuni<\/jats:italic>\n            infection in 80.6% of the patients but in only 3.5% of the controls. We conclude that the role of\n            <jats:italic>C. jejuni<\/jats:italic>\n            in triggering GBS has been greatly underestimated.\n          <\/jats:p>","DOI":"10.1128\/cvi.00065-06","type":"journal-article","created":{"date-parts":[[2006,7,7]],"date-time":"2006-07-07T19:12:52Z","timestamp":1152299572000},"page":"779-783","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":34,"title":["Improved Serological Diagnosis Stresses the Major Role of\n            <i>Campylobacter jejuni<\/i>\n            in Triggering Guillain-Barre\u0301 Syndrome"],"prefix":"10.1128","volume":"13","author":[{"given":"Ruprecht","family":"Schmidt-Ott","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology"},{"name":"Department of Neurology"},{"name":"Department of Virology, University of Go\u0308ttingen, D-37075 Go\u0308ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology"},{"name":"Department of Neurology"},{"name":"Department of Virology, University of Go\u0308ttingen, D-37075 Go\u0308ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvia","family":"Feldmann","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology"},{"name":"Department of Neurology"},{"name":"Department of Virology, University of Go\u0308ttingen, D-37075 Go\u0308ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicitas","family":"Brass","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology"},{"name":"Department of Neurology"},{"name":"Department of Virology, University of Go\u0308ttingen, D-37075 Go\u0308ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Krone","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology"},{"name":"Department of Neurology"},{"name":"Department of Virology, University of Go\u0308ttingen, D-37075 Go\u0308ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uwe","family":"Gross","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology"},{"name":"Department of Neurology"},{"name":"Department of Virology, University of Go\u0308ttingen, D-37075 Go\u0308ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.44.2.292-298.1984"},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/0022-510X(91)90216-T","volume":"104","year":"1991","unstructured":"Boucquey, D., C. 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