{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T04:15:38Z","timestamp":1791432938873,"version":"4.3.3"},"reference-count":87,"publisher":"American Society for Microbiology","issue":"9","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Vaccine Immunol"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:named-content content-type=\"genus-species\">Toxoplasma gondii<\/jats:named-content>is a parasitic protozoan which is the cause of toxoplasmosis. Although human toxoplasmosis in healthy adults is usually asymptomatic, serious disease can occur in the case of congenital infections and immunocompromised individuals. Furthermore, despite the exact recognition of its etiology, it still presents a diagnostic problem. Diagnosis of toxoplasmosis is mainly based on the results of serological tests detecting anti-<jats:named-content content-type=\"genus-species\">T. gondii<\/jats:named-content>-specific antibodies in the patient's serum sample. The specificities and sensitivities of serology tests depend mostly on the diagnostic antigen(s) used. Most of the commercial serological kits currently available are based on<jats:named-content content-type=\"genus-species\">Toxoplasma<\/jats:named-content>lysate antigens (TLAs). In recent years, many studies showed that recombinant antigenic proteins of<jats:named-content content-type=\"genus-species\">T. gondii<\/jats:named-content>may be an alternative source of antigens which are very useful for the serodiagnosis of toxoplasmosis. This article presents a review of current studies on the application and usefulness of different<jats:named-content content-type=\"genus-species\">T. gondii<\/jats:named-content>recombinant antigens in serological tests for the diagnosis of human toxoplasmosis.<\/jats:p>","DOI":"10.1128\/cvi.00117-13","type":"journal-article","created":{"date-parts":[[2013,6,20]],"date-time":"2013-06-20T04:29:40Z","timestamp":1371702580000},"page":"1343-1351","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":115,"title":["Toxoplasma gondii Recombinant Antigens as Tools for Serodiagnosis of Human Toxoplasmosis: Current Status of Studies"],"prefix":"10.1128","volume":"20","author":[{"given":"Lucyna","family":"Holec-G\u0105sior","sequence":"first","affiliation":[{"name":"Gda\u0144sk University of Technology, Chemical Faculty, Department of Microbiology, Gda\u0144sk, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(00)00124-7"},{"key":"e_1_3_1_3_2","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1016\/S0140-6736(98)08220-8","article-title":"Mother-to-child transmission of toxoplasmosis: risk estimates for clinical counselling","volume":"353","author":"Dunn D","year":"1999","unstructured":"DunnDWallonMPeyronFPetersenEPeckhamCGilbertR. 1999. 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