{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T16:10:37Z","timestamp":1757779837749},"reference-count":19,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2009,11,1]],"date-time":"2009-11-01T00:00:00Z","timestamp":1257033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Vaccine Immunol"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Recombinant Sindbis viruses were engineered to express alternative forms of the protective antigen (PA) of\n            <jats:italic>Bacillus anthracis<\/jats:italic>\n            . The recombinant viruses induced PA-specific immunoglobulin G and neutralizing antibodies in Swiss Webster mice. Vaccination with the recombinant viruses induced immunity that offered some protection from a lethal Ames strain spore challenge and synergized the protective effects of ciprofloxacin.\n          <\/jats:p>","DOI":"10.1128\/cvi.00173-09","type":"journal-article","created":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T01:47:04Z","timestamp":1253152024000},"page":"1696-1699","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":17,"title":["Recombinant Sindbis Virus Vectors Designed To Express Protective Antigen of\n            <i>Bacillus anthracis<\/i>\n            Protect Animals from Anthrax and Display Synergy with Ciprofloxacin"],"prefix":"10.1128","volume":"16","author":[{"given":"John M.","family":"Thomas","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott T.","family":"Moen","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryan T.","family":"Gnade","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego A.","family":"Vargas-Inchaustegui","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheri M.","family":"Foltz","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Suarez","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans W.","family":"Heidner","sequence":"additional","affiliation":[{"name":"University of Texas at San Antonio, Department of Biology, San Antonio, Texas 78249"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rolf","family":"Ko\u0308nig","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology"},{"name":"Sealy Center for Vaccine Development"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashok K.","family":"Chopra","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology"},{"name":"Sealy Center for Vaccine Development"},{"name":"Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston, Texas 77555-1070"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johnny W.","family":"Peterson","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology"},{"name":"Sealy Center for Vaccine Development"},{"name":"Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston, Texas 77555-1070"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00015-08"},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/n35101999","volume":"414","year":"2001","unstructured":"Bradley, K. A., J. Mogridge, M. Mourez, R. J. Collier, and J. A. Young. 2001. Identification of the cellular receptor for anthrax toxin. Nature414:225-229.","journal-title":"Nature"},{"key":"e_1_3_2_4_2","first-page":"909","volume":"50","year":"2001","unstructured":"Centers for Disease Control. 2001. Update: investigation of bioterrorism-related anthrax and interim guidelines for exposure management and antimicrobial therapy, October 2001. Morb. Mortal. Wkly. Rep.50:909-919.","journal-title":"Morb. Mortal. Wkly. Rep."},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.3.1653-1656.2002"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.61.1.245-252.1993"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.56.5.1066-1069.1988"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00360-08"},{"key":"e_1_3_2_9_2","doi-asserted-by":"crossref","first-page":"4262","DOI":"10.1016\/j.vaccine.2008.05.068","volume":"26","year":"2008","unstructured":"Hewetson, J. F., S. F. Little, B. E. Ivins, W. M. Johnson, P. R. Pittman, J. E. Brown, S. L. Norris, and C. J. Nielsen. 2008. An in vivo passive protection assay for the evaluation of immunity in AVA-vaccinated individuals. Vaccine26:4262-4266.","journal-title":"Vaccine"},{"key":"e_1_3_2_10_2","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1196\/annals.1348.030","volume":"1082","year":"2006","unstructured":"Klinman, D. M., H. Xie, and B. E. Ivins. 2006. CpG oligonucleotides improve the protective immune response induced by the licensed anthrax vaccine. Ann. N. Y. Acad. Sci.1082:137-150.","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.3.1491-1496.2003"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.74.2.1009-1015.2006"},{"key":"e_1_3_2_13_2","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1111\/j.1365-2958.1993.tb00936.x","volume":"10","year":"1993","unstructured":"Milne, J. C., and R. J. Collier. 1993. pH-dependent permeabilization of the plasma membrane of mammalian cells by anthrax protective antigen. Mol. Microbiol.10:647-653.","journal-title":"Mol. Microbiol."},{"key":"e_1_3_2_14_2","doi-asserted-by":"crossref","first-page":"758","DOI":"10.4161\/cc.6.6.3991","volume":"6","year":"2007","unstructured":"Muehlbauer, S. M., T. H. Evering, G. Bonuccelli, R. C. Squires, A. W. Ashton, S. A. Porcelli, M. P. Lisanti, and J. Brojatsch. 2007. Anthrax lethal toxin kills macrophages in a strain-specific manner by apoptosis or caspase-1-mediated necrosis. Cell Cycle6:758-766.","journal-title":"Cell Cycle"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.74.2.1016-1024.2006"},{"key":"e_1_3_2_16_2","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1046\/j.1365-2672.1999.00897.x","volume":"87","year":"1999","unstructured":"Pitt, M. L., S. Little, B. E. Ivins, P. Fellows, J. Boles, J. Barth, J. Hewetson, and A. M. Friedlander. 1999. In vitro correlate of immunity in an animal model of inhalational anthrax. J. Appl. Microbiol.87:304.","journal-title":"J. Appl. Microbiol."},{"key":"e_1_3_2_17_2","doi-asserted-by":"crossref","first-page":"5170","DOI":"10.1073\/pnas.0431098100","volume":"100","year":"2003","unstructured":"Scobie, H. M., G. J. Rainey, K. A. Bradley, and J. A. Young. 2003. Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor. Proc. Natl. Acad. Sci. USA100:5170-5174.","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.10.5598-5606.2003"},{"key":"e_1_3_2_19_2","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1007\/s00253-007-1222-3","volume":"77","year":"2007","unstructured":"Wang, S., Q. Yao, J. Tao, Y. Qiao, and Z. Zhang. 2007. Co-ordinate expression of glycine betaine synthesis genes linked by the FMDV 2A region in a single open reading frame in Pichia pastoris. Appl. Microbiol. Biotechnol.77:891-899.","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.2.828-833.2005"}],"container-title":["Clinical and Vaccine Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/CVI.00173-09","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/CVI.00173-09","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T20:41:29Z","timestamp":1627591289000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/CVI.00173-09"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11]]},"references-count":19,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["10.1128\/CVI.00173-09"],"URL":"https:\/\/doi.org\/10.1128\/cvi.00173-09","relation":{},"ISSN":["1556-6811","1556-679X"],"issn-type":[{"value":"1556-6811","type":"print"},{"value":"1556-679X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,11]]},"assertion":[{"value":"2009-04-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-09-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}