{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,30]],"date-time":"2024-06-30T02:50:55Z","timestamp":1719715855463},"reference-count":14,"publisher":"American Society for Microbiology","issue":"9","license":[{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Vaccine Immunol"],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Cultures of\n            <jats:italic>Mycobacterium bovis<\/jats:italic>\n            BCG, comprising predominantly single-cell bacilli, were prepared in broth without animal-derived reagents. When formulated into a vegetable-derived lipid matrix, the vaccine was stable in vitro and was immunogenic in vivo upon feeding it to mice. This formulation could be useful for oral vaccination of wildlife against tuberculosis, where concern over transmissible prions may preclude the field use of vaccines containing animal products.\n          <\/jats:p>","DOI":"10.1128\/cvi.00198-09","type":"journal-article","created":{"date-parts":[[2009,7,2]],"date-time":"2009-07-02T01:46:33Z","timestamp":1246499193000},"page":"1378-1380","update-policy":"http:\/\/dx.doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":3,"title":["An Oral\n            <i>Mycobacterium bovis<\/i>\n            BCG Vaccine for Wildlife Produced in the Absence of Animal-Derived Reagents"],"prefix":"10.1128","volume":"16","author":[{"given":"Martin L.","family":"Cross","sequence":"first","affiliation":[{"name":"Centre for Innovation, University of Otago, P.O. 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