{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T13:17:15Z","timestamp":1789996635149,"version":"4.0.1"},"reference-count":17,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Vaccine Immunol"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            The C epitope of\n            <jats:named-content content-type=\"genus-species\">Brucella<\/jats:named-content>\n            O-polysaccharide (O-PS) has so far lacked definitive structural identity. Revised structures for this antigen revealed a unique capping perosamine tetrasaccharide consisting of a sequence of 1,2:1,3:1,2 interresidue linkages. Here, using synthetic oligosaccharide glycoconjugates, the \u03b1-1,3 linkage of the O-PS is shown to be an integral structural requirement of this epitope. Although A-dominant strains possess only one or two copies of the capping tetrasaccharide, this creates a unique pentasaccharide antigenic determinant with the linkage sequence 1,2:1,3:1,2:1,2 that is always present in major pathogenic\n            <jats:named-content content-type=\"genus-species\">Brucella<\/jats:named-content>\n            species.\n          <\/jats:p>","DOI":"10.1128\/cvi.00225-15","type":"journal-article","created":{"date-parts":[[2015,6,11]],"date-time":"2015-06-11T02:01:58Z","timestamp":1433988118000},"page":"979-982","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":14,"title":["Monoclonal Antibody-Defined Specific C Epitope of Brucella O-Polysaccharide Revisited"],"prefix":"10.1128","volume":"22","author":[{"given":"Michel S.","family":"Zygmunt","sequence":"first","affiliation":[{"name":"INRA, UMR1282 Infectiologie et Sant\u00e9 Publique, Nouzilly, France"},{"name":"Universit\u00e9 Fran\u00e7ois Rabelais de Tours, UMR1282 Infectiologie et Sant\u00e9 Publique, Tours, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R.","family":"Bundle","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. Vijaya","family":"Ganesh","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Guiard","sequence":"additional","affiliation":[{"name":"Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Cloeckaert","sequence":"additional","affiliation":[{"name":"INRA, UMR1282 Infectiologie et Sant\u00e9 Publique, Nouzilly, France"},{"name":"Universit\u00e9 Fran\u00e7ois Rabelais de Tours, UMR1282 Infectiologie et Sant\u00e9 Publique, Tours, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.31.12.3136-3141.1993"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/CDLI.5.6.862-870.1998"},{"key":"e_1_3_1_4_2","volume-title":"Techniques for the brucellosis laboratory","author":"Alton GG","year":"1988","unstructured":"Alton GG, Jones LM, Angus RD, Verger JM. 1988. 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L.","family":"Burns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":17,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["10.1128\/CVI.00225-15"],"URL":"https:\/\/doi.org\/10.1128\/cvi.00225-15","relation":{},"ISSN":["1556-6811","1556-679X"],"issn-type":[{"value":"1556-6811","type":"print"},{"value":"1556-679X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8]]},"assertion":[{"value":"2015-04-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-06-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-07-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}