{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T14:41:50Z","timestamp":1783953710611,"version":"3.55.0"},"reference-count":32,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2008,1,1]],"date-time":"2008-01-01T00:00:00Z","timestamp":1199145600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Vaccine Immunol"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Four different recombinant antigens derived from\n            <jats:italic>Echinococcus granulosus<\/jats:italic>\n            , designated B1t, B2t, E14t, and C317, were tested with enzyme-linked immunosorbent assays (ELISAs) for the detection of specific immunoglobulin G (IgG) in patients with unilocular hydatid disease (UHD). The results were compared to those obtained with hydatid fluid and were subjected to receiver operator characteristic analysis. The diagnostic performance of the above-listed proteins was defined with respect to their specificity, sensitivity, and predictive values (PV); the influence of cyst location; and usefulness in the follow-up of surgical treatment for UHD and in the determination of whether or not patients have been surgically cured of UHD. The best diagnostic results were obtained with the anti-B2t IgG ELISA, with 91.2% sensitivity, 93% specificity, and high positive and negative PV (89.4 and 94.2, respectively). In addition, this diagnostic tool proved to be useful for the follow-up of surgically treated UHD patients. The anti-B2t IgG ELISA may find an application in the serodiagnosis of UHD in clinical laboratories.\n          <\/jats:p>","DOI":"10.1128\/cvi.00363-07","type":"journal-article","created":{"date-parts":[[2007,11,8]],"date-time":"2007-11-08T02:38:58Z","timestamp":1194489538000},"page":"147-153","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":60,"title":["Usefulness of Four Different\n            <i>Echinococcus granulosus<\/i>\n            Recombinant Antigens for Serodiagnosis of Unilocular Hydatid Disease (UHD) and Postsurgical Follow-Up of Patients Treated for UHD"],"prefix":"10.1128","volume":"15","author":[{"given":"Ana","family":"Herna\u0301ndez-Gonza\u0301lez","sequence":"first","affiliation":[{"name":"IRNASA, CSIC, Cordel de Merinas, 50, 37008 Salamanca, Spain"},{"name":"Laboratorio de Parasitologi\u0301a, CIETUS, Facultad de Farmacia, Universidad de Salamanca, Campo Charro, s\/n, 37007 Salamanca, Spain"},{"name":"Departamento de Estadi\u0301stica, Facultad de Biologi\u0301a, Universidad de Salamanca, Campo Charro, s\/n, 37007 Salamanca, Spain"},{"name":"Hospital Universitario de Valladolid, Ramo\u0301n y Cajal, 3, 47003 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Muro","sequence":"additional","affiliation":[{"name":"IRNASA, CSIC, Cordel de Merinas, 50, 37008 Salamanca, Spain"},{"name":"Laboratorio de Parasitologi\u0301a, CIETUS, Facultad de Farmacia, Universidad de Salamanca, Campo Charro, s\/n, 37007 Salamanca, Spain"},{"name":"Departamento de Estadi\u0301stica, Facultad de Biologi\u0301a, Universidad de Salamanca, Campo Charro, s\/n, 37007 Salamanca, Spain"},{"name":"Hospital Universitario de Valladolid, Ramo\u0301n y Cajal, 3, 47003 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inmaculada","family":"Barrera","sequence":"additional","affiliation":[{"name":"IRNASA, CSIC, Cordel de Merinas, 50, 37008 Salamanca, Spain"},{"name":"Laboratorio de Parasitologi\u0301a, CIETUS, Facultad de Farmacia, Universidad de Salamanca, Campo Charro, s\/n, 37007 Salamanca, Spain"},{"name":"Departamento de Estadi\u0301stica, Facultad de Biologi\u0301a, Universidad de Salamanca, Campo Charro, s\/n, 37007 Salamanca, Spain"},{"name":"Hospital Universitario de Valladolid, Ramo\u0301n y Cajal, 3, 47003 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Ramos","sequence":"additional","affiliation":[{"name":"IRNASA, CSIC, Cordel de Merinas, 50, 37008 Salamanca, Spain"},{"name":"Laboratorio de Parasitologi\u0301a, CIETUS, Facultad de Farmacia, Universidad de Salamanca, Campo Charro, s\/n, 37007 Salamanca, Spain"},{"name":"Departamento de Estadi\u0301stica, Facultad de Biologi\u0301a, Universidad de Salamanca, Campo Charro, s\/n, 37007 Salamanca, Spain"},{"name":"Hospital Universitario de Valladolid, Ramo\u0301n y Cajal, 3, 47003 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Ordun\u0303a","sequence":"additional","affiliation":[{"name":"IRNASA, CSIC, Cordel de Merinas, 50, 37008 Salamanca, Spain"},{"name":"Laboratorio de Parasitologi\u0301a, CIETUS, Facultad de Farmacia, Universidad de Salamanca, Campo Charro, s\/n, 37007 Salamanca, Spain"},{"name":"Departamento de Estadi\u0301stica, Facultad de Biologi\u0301a, Universidad de Salamanca, Campo Charro, s\/n, 37007 Salamanca, Spain"},{"name":"Hospital Universitario de Valladolid, Ramo\u0301n y Cajal, 3, 47003 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar","family":"Siles-Lucas","sequence":"additional","affiliation":[{"name":"IRNASA, CSIC, Cordel de Merinas, 50, 37008 Salamanca, Spain"},{"name":"Laboratorio de Parasitologi\u0301a, CIETUS, Facultad de Farmacia, Universidad de Salamanca, Campo Charro, s\/n, 37007 Salamanca, Spain"},{"name":"Departamento de Estadi\u0301stica, Facultad de Biologi\u0301a, Universidad de Salamanca, Campo Charro, s\/n, 37007 Salamanca, Spain"},{"name":"Hospital Universitario de Valladolid, Ramo\u0301n y Cajal, 3, 47003 Valladolid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"64","DOI":"10.4269\/ajtmh.1994.50.64","volume":"50","year":"1994","unstructured":"Babba, H., A. 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