{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:01:33Z","timestamp":1791223293840,"version":"4.1.0"},"reference-count":8,"publisher":"American Society for Microbiology","issue":"12","license":[{"start":{"date-parts":[[2012,12,1]],"date-time":"2012-12-01T00:00:00Z","timestamp":1354320000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Vaccine Immunol"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    We compared the performance of four assays for the detection of cryptococcal antigen in serum samples (\n                    <jats:italic>n<\/jats:italic>\n                    = 634) and cerebrospinal fluid (CSF) samples (\n                    <jats:italic>n<\/jats:italic>\n                    = 51). Compared to latex agglutination, the sensitivity and specificity of the Premier enzyme immunoassay (EIA), Alpha CrAg EIA, and CrAg lateral flow assay (LFA) were 55.6 and 100%, 100 and 99.7%, and 100 and 99.8%, respectively, from serum samples. There was 100% agreement among the four tests for CSF samples, with 18 samples testing positive by each of the assays.\n                  <\/jats:p>","DOI":"10.1128\/cvi.00446-12","type":"journal-article","created":{"date-parts":[[2012,10,18]],"date-time":"2012-10-18T21:08:21Z","timestamp":1350594501000},"page":"1988-1990","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":99,"title":["Comparison of Four Assays for the Detection of Cryptococcal Antigen"],"prefix":"10.1128","volume":"19","author":[{"given":"M. J.","family":"Binnicker","sequence":"first","affiliation":[{"name":"Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. J.","family":"Jespersen","sequence":"additional","affiliation":[{"name":"Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. E.","family":"Bestrom","sequence":"additional","affiliation":[{"name":"Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. O.","family":"Rollins","sequence":"additional","affiliation":[{"name":"Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, Minnesota, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1080\/13693780802607400","article-title":"Evaluation of three commercial latex agglutination kits and a commercial enzyme immunoassay for the detection of cryptococcal antigen","volume":"47","author":"Babady NE","year":"2009","unstructured":"BabadyNE . 2009. Evaluation of three commercial latex agglutination kits and a commercial enzyme immunoassay for the detection of cryptococcal antigen. Med. Mycol. 47: 336\u2013 338.","journal-title":"Med. Mycol."},{"key":"e_1_3_2_3_2","volume-title":"C. neoformans cryptococcosis: cryptococcosis statistics. Department of Health and Human Services","author":"CDC","year":"2012","unstructured":"CDC . 5 January 2012 posting date. C. neoformans cryptococcosis: cryptococcosis statistics. Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta, GA. http:\/\/www.cdc.gov\/fungal\/cryptococcosis-neoformans\/statistics.html."},{"key":"e_1_3_2_4_2","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1093\/cid\/cir613","article-title":"Evaluation of a novel point-of-care cryptococcal antigen test on serum, plasma, and urine from patients with HIV-associated cryptococcal meningitis","volume":"53","author":"Jarvis JN","year":"2011","unstructured":"JarvisJN . 2011. Evaluation of a novel point-of-care cryptococcal antigen test on serum, plasma, and urine from patients with HIV-associated cryptococcal meningitis. Clin. Infect. Dis. 53: 1019\u2013 1023.","journal-title":"Clin. Infect. Dis."},{"key":"e_1_3_2_5_2","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1093\/ajcp\/109.5.634","article-title":"Comparison of two rapid latex agglutination tests for detection of cryptococcal capsular polysaccharide","volume":"109","author":"Jaye DL","year":"1998","unstructured":"JayeDL WaitesK ParkerB BraggS MoserSA . 1998. Comparison of two rapid latex agglutination tests for detection of cryptococcal capsular polysaccharide. Am. J. Clin. Pathol. 109: 634\u2013 641.","journal-title":"Am. J. Clin. Pathol."},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.32.9.2309-2311.1994"},{"key":"e_1_3_2_7_2","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/cid\/cir379","article-title":"Evaluation of a newly developed lateral flow immunoassay for the diagnosis of cryptococcosis","volume":"53","author":"Lindsley MD","year":"2011","unstructured":"LindsleyMD . 2011. Evaluation of a newly developed lateral flow immunoassay for the diagnosis of cryptococcosis. Clin. Infect. Dis. 53: 321\u2013 325.","journal-title":"Clin. Infect. Dis."},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.05052-11"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.32.7.1680-1684.1994"}],"container-title":["Clinical and Vaccine Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/CVI.00446-12","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/CVI.00446-12","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T16:46:20Z","timestamp":1627577180000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/CVI.00446-12"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":8,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["10.1128\/CVI.00446-12"],"URL":"https:\/\/doi.org\/10.1128\/cvi.00446-12","relation":{},"ISSN":["1556-6811","1556-679X"],"issn-type":[{"value":"1556-6811","type":"print"},{"value":"1556-679X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12]]},"assertion":[{"value":"2012-07-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-10-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-11-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}