{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T08:47:45Z","timestamp":1778575665156,"version":"3.51.4"},"reference-count":3,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Vaccine Immunol"],"published-print":{"date-parts":[[2008,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            Patients with histoplasmosis may test falsely negative for\n            <jats:italic>Histoplasma capsulatum<\/jats:italic>\n            antigenuria. In some cases antigen is present at levels below the assay's detection limit, and ultrafiltration could improve sensitivity. Antigen was detected following ultrafiltration in 73.8% of falsely negative specimens versus 2% of controls. Ultrafiltration improved sensitivity with a small reduction in specificity.\n          <\/jats:p>","DOI":"10.1128\/cvi.00493-07","type":"journal-article","created":{"date-parts":[[2008,2,28]],"date-time":"2008-02-28T02:09:53Z","timestamp":1204164593000},"page":"726-728","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":15,"title":["Detection of\n            <i>Histoplasma capsulatum<\/i>\n            Antigenuria by Ultrafiltration of Samples with False-Negative Results"],"prefix":"10.1128","volume":"15","author":[{"given":"Lindsey","family":"Egan","sequence":"first","affiliation":[{"name":"MiraVista Diagnostics, Indianapolis, Indiana"},{"name":"Indiana University School of Medicine, Department of Pathology, Wishard Memorial Hospital, 1001 West Tenth Street, Indianapolis, Indiana 46202"},{"name":"Indiana University School of Medicine, Department of Pulmonary Medicine, Roudebush Veterans\u2019 Administration Hospital, 1481 West Tenth Street, Indianapolis, Indiana 46202"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia A.","family":"Connolly","sequence":"additional","affiliation":[{"name":"MiraVista Diagnostics, Indianapolis, Indiana"},{"name":"Indiana University School of Medicine, Department of Pathology, Wishard Memorial Hospital, 1001 West Tenth Street, Indianapolis, Indiana 46202"},{"name":"Indiana University School of Medicine, Department of Pulmonary Medicine, Roudebush Veterans\u2019 Administration Hospital, 1481 West Tenth Street, Indianapolis, Indiana 46202"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deanna","family":"Fuller","sequence":"additional","affiliation":[{"name":"MiraVista Diagnostics, Indianapolis, Indiana"},{"name":"Indiana University School of Medicine, Department of Pathology, Wishard Memorial Hospital, 1001 West Tenth Street, Indianapolis, Indiana 46202"},{"name":"Indiana University School of Medicine, Department of Pulmonary Medicine, Roudebush Veterans\u2019 Administration Hospital, 1481 West Tenth Street, Indianapolis, Indiana 46202"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas E.","family":"Davis","sequence":"additional","affiliation":[{"name":"MiraVista Diagnostics, Indianapolis, Indiana"},{"name":"Indiana University School of Medicine, Department of Pathology, Wishard Memorial Hospital, 1001 West Tenth Street, Indianapolis, Indiana 46202"},{"name":"Indiana University School of Medicine, Department of Pulmonary Medicine, Roudebush Veterans\u2019 Administration Hospital, 1481 West Tenth Street, Indianapolis, Indiana 46202"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"III","given":"John","family":"Witt","sequence":"additional","affiliation":[{"name":"MiraVista Diagnostics, Indianapolis, Indiana"},{"name":"Indiana University School of Medicine, Department of Pathology, Wishard Memorial Hospital, 1001 West Tenth Street, Indianapolis, Indiana 46202"},{"name":"Indiana University School of Medicine, Department of Pulmonary Medicine, Roudebush Veterans\u2019 Administration Hospital, 1481 West Tenth Street, Indianapolis, Indiana 46202"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth S.","family":"Knox","sequence":"additional","affiliation":[{"name":"MiraVista Diagnostics, Indianapolis, Indiana"},{"name":"Indiana University School of Medicine, Department of Pathology, Wishard Memorial Hospital, 1001 West Tenth Street, Indianapolis, Indiana 46202"},{"name":"Indiana University School of Medicine, Department of Pulmonary Medicine, Roudebush Veterans\u2019 Administration Hospital, 1481 West Tenth Street, Indianapolis, Indiana 46202"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chadi A.","family":"Hage","sequence":"additional","affiliation":[{"name":"MiraVista Diagnostics, Indianapolis, Indiana"},{"name":"Indiana University School of Medicine, Department of Pathology, Wishard Memorial Hospital, 1001 West Tenth Street, Indianapolis, Indiana 46202"},{"name":"Indiana University School of Medicine, Department of Pulmonary Medicine, Roudebush Veterans\u2019 Administration Hospital, 1481 West Tenth Street, Indianapolis, Indiana 46202"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. Joseph","family":"Wheat","sequence":"additional","affiliation":[{"name":"MiraVista Diagnostics, Indianapolis, Indiana"},{"name":"Indiana University School of Medicine, Department of Pathology, Wishard Memorial Hospital, 1001 West Tenth Street, Indianapolis, Indiana 46202"},{"name":"Indiana University School of Medicine, Department of Pulmonary Medicine, Roudebush Veterans\u2019 Administration Hospital, 1481 West Tenth Street, Indianapolis, Indiana 46202"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00071-07"},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.rmed.2006.04.017","volume":"101","year":"2007","unstructured":"Hage, C. A., T. E. Davis, L. Egan, M. Parker, D. Fuller, A. M. LeMonte, M. Durkin, P. Connelly, L. J. Wheat, D. Blue-Hnidy, and K. S. Knox. 2007. Diagnosis of pulmonary histoplasmosis and blastomycosis by detection of antigen in bronchoalveolar lavage fluid using an improved second-generation enzyme-linked immunoassay. Respir. Med.101:43-47.","journal-title":"Respir. Med."},{"key":"e_1_3_2_4_2","first-page":"e50-e54","volume":"44","year":"2007","unstructured":"Kuberski, T., R. Myers, L. J. Wheat, B. M. Kubak, D. Bruckner, and D. Peuges. 2007. Diagnosis of coccidioidomycosis by antigen detection using cross-reaction with a Histoplasma antigen. Clin. Infect. Dis.44:e50-e54.","journal-title":"Clin. Infect. Dis."}],"container-title":["Clinical and Vaccine Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/CVI.00493-07","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/CVI.00493-07","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T20:39:47Z","timestamp":1627591187000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/CVI.00493-07"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":3,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["10.1128\/CVI.00493-07"],"URL":"https:\/\/doi.org\/10.1128\/cvi.00493-07","relation":{},"ISSN":["1556-6811","1556-679X"],"issn-type":[{"value":"1556-6811","type":"print"},{"value":"1556-679X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4]]},"assertion":[{"value":"2007-12-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-02-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}