{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T06:26:55Z","timestamp":1789626415941,"version":"build-2803163510"},"reference-count":38,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["AI109591-01A1"],"award-info":[{"award-number":["AI109591-01A1"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Clin Vaccine Immunol"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            For years, studies of the immune response to\n            <jats:named-content content-type=\"genus-species\">Giardia lamblia<\/jats:named-content>\n            infection focused on the production of IgA by infected hosts and antigenic variation by the parasite to escape destruction by this IgA. A new study by Hanevik and colleagues (C. S. Saghaug, S. S\u00f8rnes, D. Peirasmaki, S. Sv\u00e4rd, N. Langeland, and K. Hanevik, Clin Vaccine Immunol 23:11\u201318, 2016,\n            <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/dx.doi.org\/10.1128\/CVI.00419-15\">http:\/\/dx.doi.org\/10.1128\/CVI.00419-15<\/jats:ext-link>\n            ) highlights the emerging role of interleukin-17 (IL-17) in immunity to this parasite. Along with recent studies of\n            <jats:named-content content-type=\"genus-species\">Giardia<\/jats:named-content>\n            infections of animals, this work shows that IL-17 appears to be essential for the control of these infections and to be a key factor linking cellular and humoral immune responses.\n          <\/jats:p>","DOI":"10.1128\/cvi.00648-15","type":"journal-article","created":{"date-parts":[[2015,11,19]],"date-time":"2015-11-19T03:34:22Z","timestamp":1447904062000},"page":"2-5","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":25,"title":["Control of Giardiasis by Interleukin-17 in Humans and Mice\u2014Are the Questions All Answered?"],"prefix":"10.1128","volume":"23","author":[{"given":"Steven M.","family":"Singer","sequence":"first","affiliation":[{"name":"Department of Biology, Georgetown University, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00419-15"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2005.05.006"},{"key":"e_1_3_1_4_2","first-page":"160","article-title":"Role of IL-2, IL-4 and IL-10 in patients infected with Giardia lamblia","volume":"29","author":"Bayraktar MR","year":"2005","unstructured":"Bayraktar MR, Mehmet N, Durmaz R. 2005. Role of IL-2, IL-4 and IL-10 in patients infected with Giardia lamblia. 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