{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T13:09:59Z","timestamp":1753880999225,"version":"3.41.2"},"reference-count":19,"publisher":"American Society for Microbiology","issue":"4","license":[{"start":{"date-parts":[[2014,7,31]],"date-time":"2014-07-31T00:00:00Z","timestamp":1406764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"},{"start":{"date-parts":[[2014,8,28]],"date-time":"2014-08-28T00:00:00Z","timestamp":1409184000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Genome Announc"],"published-print":{"date-parts":[[2014,8,28]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We report the whole-genome sequence of an extensively drug-resistant (XDR) tuberculosis (TB) strain of Latin American\u2013Mediterranean (LAM) lineage. This strain is phenotypically resistant to aminoglycosides, but carries no related mutations in\n            <jats:italic>rrs<\/jats:italic>\n            ,\n            <jats:italic>tlyA<\/jats:italic>\n            , and\n            <jats:italic>eis<\/jats:italic>\n            . Through genome analysis comparison with 16 XDR strains, we found 218 non-synonymous single nucleotide polymorphisms (SNPs) shared that could confer resistance.\n          <\/jats:p>","DOI":"10.1128\/genomea.00759-14","type":"journal-article","created":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T02:52:36Z","timestamp":1406861556000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":6,"title":["Genome Analysis of 17 Extensively Drug-Resistant Strains Reveals New Potential Mutations for Resistance"],"prefix":"10.1128","volume":"2","author":[{"given":"H.","family":"Guio","sequence":"first","affiliation":[{"name":"Laboratorio de Biotecnolog\u00eda y Biolog\u00eda Molecular, Instituto Nacional de Salud (INS), Lima, Peru"},{"name":"Asociaci\u00f3n Latinoamericana de Biotecnolog\u00eda (NGO-ALBIOTEC), Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Tarazona","sequence":"additional","affiliation":[{"name":"Laboratorio de Biotecnolog\u00eda y Biolog\u00eda Molecular, Instituto Nacional de Salud (INS), Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Galarza","sequence":"additional","affiliation":[{"name":"Laboratorio de Biotecnolog\u00eda y Biolog\u00eda Molecular, Instituto Nacional de Salud (INS), Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Borda","sequence":"additional","affiliation":[{"name":"Laboratorio de Biotecnolog\u00eda y Biolog\u00eda Molecular, Instituto Nacional de Salud (INS), Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Curitomay","sequence":"additional","affiliation":[{"name":"Departamento de Neumolog\u00eda, Hospital Nacional Hip\u00f3lito Unanue, Lima, Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","unstructured":"ESNPyCTB\n. 2012. Informe de la Estrategia Sanitaria Nacional de Prevenci\u00f3n y Control de la Tuberculosis sobre Situaci\u00f3n y Control de TB-MDR y TB-XDR en Per\u00fa. Estrategia Sanitaria Nacional de Prevenci\u00f3n y Control de la Tuberculosis."},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(08)70260-3"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69573-1"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01392-06"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts544"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp324"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2744"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt1226"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000002"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/1574-6968.12238"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00438-013-0758-4"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2735"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2747"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0056577"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/genomeA.00056-12"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0007778"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bti176"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-13-S7-S6"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-4-41"}],"container-title":["Genome Announcements"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/genomeA.00759-14","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/genomeA.00759-14","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T19:59:41Z","timestamp":1646423981000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/genomeA.00759-14"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,28]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,8,28]]}},"alternative-id":["10.1128\/genomeA.00759-14"],"URL":"https:\/\/doi.org\/10.1128\/genomea.00759-14","relation":{},"ISSN":["2169-8287"],"issn-type":[{"type":"electronic","value":"2169-8287"}],"subject":[],"published":{"date-parts":[[2014,8,28]]},"assertion":[{"value":"2014-07-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-07-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-07-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00759-14"}}