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Uptake of manganese (Mn) is essential for\n                    <jats:named-content content-type=\"genus-species\">Enterococcus faecalis<\/jats:named-content>\n                    growth and virulence; however, it is not known how this organism prevents Mn toxicity. In this study, we examine the role of the highly conserved MntE transporter in\n                    <jats:named-content content-type=\"genus-species\">E. faecalis<\/jats:named-content>\n                    Mn homeostasis and virulence. We show that inactivation of\n                    <jats:italic>mntE<\/jats:italic>\n                    results in growth restriction in the presence of excess Mn, but not other metals, demonstrating its specific role in Mn detoxification.\n                  <\/jats:p>","DOI":"10.1128\/iai.00058-20","type":"journal-article","created":{"date-parts":[[2020,3,26]],"date-time":"2020-03-26T09:06:02Z","timestamp":1585213562000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":18,"title":["Enterococcus faecalis Manganese Exporter MntE Alleviates Manganese Toxicity and Is Required for Mouse Gastrointestinal Colonization"],"prefix":"10.1128","volume":"88","author":[{"given":"Ling Ning","family":"Lam","sequence":"first","affiliation":[{"name":"Singapore Centre for Environmental Life Science Engineering, Nanyang Technological University, Singapore"},{"name":"School of Biological Sciences, Nanyang Technological University, 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