{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:42:58Z","timestamp":1790962978727,"version":"4.1.0"},"reference-count":47,"publisher":"American Society for Microbiology","issue":"9","license":[{"start":{"date-parts":[[2018,8,22]],"date-time":"2018-08-22T00:00:00Z","timestamp":1534896000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"crossref","award":["097395\/Z\/11\/Z"],"award-info":[{"award-number":["097395\/Z\/11\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Infect Immun"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:p>\n            Vivax malaria remains one of the most serious and neglected tropical diseases, with 132 to 391 million clinical cases per year and 2.5 billion people at risk of infection. A vaccine against\n            <jats:named-content content-type=\"genus-species\">Plasmodium vivax<\/jats:named-content>\n            could have more impact than any other intervention, and the use of a vaccine targeting multiple antigens may result in higher efficacy against sporozoite infection than targeting a single antigen.\n          <\/jats:p>","DOI":"10.1128\/iai.00114-18","type":"journal-article","created":{"date-parts":[[2018,7,9]],"date-time":"2018-07-09T10:42:56Z","timestamp":1531132976000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":37,"title":["Tailoring a Plasmodium vivax Vaccine To Enhance Efficacy through a Combination of a CSP Virus-Like Particle and TRAP Viral Vectors"],"prefix":"10.1128","volume":"86","author":[{"given":"Erwan","family":"Atcheson","sequence":"first","affiliation":[{"name":"The Jenner Institute, University of Oxford, Oxford, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolis","family":"Bauza","sequence":"additional","affiliation":[{"name":"The Jenner Institute, University of Oxford, Oxford, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed M.","family":"Salman","sequence":"additional","affiliation":[{"name":"The Jenner Institute, University of Oxford, Oxford, United Kingdom"},{"name":"Leiden Malaria Research Group, Department of Parasitology, Center of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Alves","sequence":"additional","affiliation":[{"name":"The Jenner Institute, University of Oxford, Oxford, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Blight","sequence":"additional","affiliation":[{"name":"The Jenner Institute, University of Oxford, Oxford, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha Eva","family":"Viveros-Sandoval","sequence":"additional","affiliation":[{"name":"Laboratorio de Hemostasia y Biolog\u00eda Vascular, Divisi\u00f3n de Estudios de Posgrado, Facultad de Ciencias M\u00e9dicas y Biol\u00f3gicas Dr. Ignacio Ch\u00e1vez, Universidad Michoacana de San Nicol\u00e1s de Hidalgo (UMSNH), Morelia, Michoac\u00e1n, Mexico"},{"name":"UMSNH-Oxford University Clinical Research Laboratory, Faculty of Biological and Medical Sciences Dr. Ignacio Ch\u00e1vez, Universidad Michoacana de San Nicol\u00e1s de Hidalgo, Morelia, Michoac\u00e1n, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris J.","family":"Janse","sequence":"additional","affiliation":[{"name":"Leiden Malaria Research Group, Department of Parasitology, Center of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahid M.","family":"Khan","sequence":"additional","affiliation":[{"name":"Leiden Malaria Research Group, Department of Parasitology, Center of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian V. S.","family":"Hill","sequence":"additional","affiliation":[{"name":"The Jenner Institute, University of Oxford, Oxford, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2648-1696","authenticated-orcid":false,"given":"Arturo","family":"Reyes-Sandoval","sequence":"additional","affiliation":[{"name":"The Jenner Institute, University of Oxford, Oxford, United Kingdom"},{"name":"UMSNH-Oxford University Clinical Research Laboratory, Faculty of Biological and Medical Sciences Dr. Ignacio Ch\u00e1vez, Universidad Michoacana de San Nicol\u00e1s de Hidalgo, Morelia, Michoac\u00e1n, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-7-S1-S9"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.4161\/hv.26157"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2007.77.79"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001814"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2006.75.111"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003193"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.07.107"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01063-15"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiw244"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004423"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2011.09-0516"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0040337"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-6851(02)00017-8"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2013.10.041"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep46482"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01187-13"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1982.31.1291"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiu579"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001994"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1208394"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1102287"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms3836"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1827210"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir850"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2009.10.022"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1586\/erv.12.140"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1586\/14760584.2013.814822"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0041451"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-07246-0"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.07.017"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep46621"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.4110\/in.2015.15.2.51"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40264-015-0350-4"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.14-0767"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.30875\/9f925144-en"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2006.53"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2006.88"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1006\/meth.1997.0507"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-11-103"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-026-7_30"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.6985745"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1101004"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444906029799"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034255"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00740-09"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1086\/513996"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1100302"}],"container-title":["Infection and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/IAI.00114-18","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/IAI.00114-18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T11:05:54Z","timestamp":1646478354000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/IAI.00114-18"}},"subtitle":[],"editor":[{"given":"John H.","family":"Adams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":47,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["10.1128\/IAI.00114-18"],"URL":"https:\/\/doi.org\/10.1128\/iai.00114-18","relation":{},"ISSN":["0019-9567","1098-5522"],"issn-type":[{"value":"0019-9567","type":"print"},{"value":"1098-5522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"2018-02-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00114-18"}}