{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T17:17:46Z","timestamp":1793812666268,"version":"4.6.1"},"reference-count":145,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T00:00:00Z","timestamp":1770681600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Infect Immun"],"published-print":{"date-parts":[[2026,2,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Salmonella enterica<\/jats:italic>\n                      infections are a major cause of morbidity and mortality worldwide, especially in sub-Saharan Africa and in the Asian continent, and are increasingly associated with antimicrobial resistance.\n                      <jats:italic toggle=\"yes\">Salmonella enterica<\/jats:italic>\n                      serovars Typhi and Paratyphi A, B, and C cause enteric fever, while non-typhoidal\n                      <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                      serovars (usually Typhimurium and Enteritidis) cause mainly gastroenteritis which can lead to systemic infections. Vaccines are only licensed against\n                      <jats:italic toggle=\"yes\">S<\/jats:italic>\n                      . Typhi, but different combinations are in clinical development to prevent\n                      <jats:italic toggle=\"yes\">S<\/jats:italic>\n                      . Typhi and\n                      <jats:italic toggle=\"yes\">S<\/jats:italic>\n                      . Paratyphi A or\n                      <jats:italic toggle=\"yes\">S<\/jats:italic>\n                      . Typhi and non-typhoidal\n                      <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                      . Here, we describe elements of the pathogenesis of and immunity to\n                      <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                      that are critical to guide the rational design of vaccines. We highlight how the choice of appropriate immunogenic and protective antigens would be essential to achieve the maximum coverage of serovars in a multivalent\n                      <jats:italic toggle=\"yes\">Salmonella<\/jats:italic>\n                      vaccine. The principal vaccines under development at the preclinical and clinical stages are described, together with considerations on the technical and clinical feasibility of moving combination vaccines toward licensure.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1128\/iai.00118-25","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T14:00:11Z","timestamp":1767708011000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":5,"title":["Multivalent vaccines for invasive\n                    <i>Salmonella<\/i>\n                    disease: need, rationale, and immunological foundations"],"prefix":"10.1128","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3838-4962","authenticated-orcid":true,"given":"Pietro","family":"Mastroeni","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/013meh722","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Cambridge","place":["Cambridge, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0170-1285","authenticated-orcid":true,"given":"Omar","family":"Rossi","sequence":"additional","affiliation":[{"name":"GSK, Vaccines Institute for Global Health (GVGH)","place":["Siena, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8243-3181","authenticated-orcid":true,"given":"Francesca","family":"Micoli","sequence":"additional","affiliation":[{"name":"GSK, Vaccines Institute for Global Health (GVGH)","place":["Siena, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(18)30685-6"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2024.102883"},{"key":"e_1_3_1_4_2","first-page":"346","article-title":"The global burden of typhoid fever","volume":"82","author":"Crump JA","year":"2004","unstructured":"Crump JA, Luby SP, Mintz ED. 2004. The global burden of typhoid fever. Bull World Health Organ 82:346\u2013353.","journal-title":"Bull World Health Organ"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2017.11.014"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofad020"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms11092233"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmicrobiol.2015.23"},{"key":"e_1_3_1_9_2","unstructured":"Institute for Health Metrics and Evaluation. 2023. Available from: https:\/\/vizhub.healthdata.org\/gbd-results\/"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.3201\/eid2106.140999"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(21)00615-0"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micres.2023.127488"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-023-00480-z"},{"key":"e_1_3_1_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s44197-023-00160-x"},{"key":"e_1_3_1_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-41152-6"},{"key":"e_1_3_1_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-020-01652-4"},{"key":"e_1_3_1_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-025-10478-5"},{"key":"e_1_3_1_18_2","unstructured":"Estimating the impact of vaccines in reducing antimicrobial resistance and antibiotic use: technical report. 2024. Available from: https:\/\/www.who.int\/publications\/i\/item\/9789240098787"},{"key":"e_1_3_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanmic.2024.101040"},{"key":"e_1_3_1_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-020-00506-3"},{"key":"e_1_3_1_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofad041"},{"key":"e_1_3_1_22_2","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000677"},{"key":"e_1_3_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1286-4579(01)01488-5"},{"key":"e_1_3_1_24_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.139.5.1189"},{"key":"e_1_3_1_25_2","first-page":"74","article-title":"The kinetics of blood clearance o isotopically labelled Salmonella entertidis by the reticulo-endothelial system in mice","volume":"3","author":"BIOZZI G","year":"1960","unstructured":"BIOZZI G, HOWARD JG, HALPERN BN, STIFFEL C, MOUTON D. 1960. The kinetics of blood clearance o isotopically labelled Salmonella entertidis by the reticulo-endothelial system in mice. Immunology 3:74\u201389.","journal-title":"Immunology"},{"key":"e_1_3_1_26_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.186.4.569"},{"key":"e_1_3_1_27_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1462-5822.2001.00137.x"},{"key":"e_1_3_1_28_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1462-5822.2003.00296.x"},{"key":"e_1_3_1_29_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.10.5881-5891.2003"},{"key":"e_1_3_1_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/0882-4010(91)90091-n"},{"key":"e_1_3_1_31_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.63.9.3674-3682.1995"},{"key":"e_1_3_1_32_2","doi-asserted-by":"publisher","DOI":"10.1006\/mpat.1993.1046"},{"key":"e_1_3_1_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.67.2.478-483.1999"},{"key":"e_1_3_1_34_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.64.1.189-196.1996"},{"key":"e_1_3_1_35_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.192.2.237"},{"key":"e_1_3_1_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/0882-4010(92)90014-f"},{"key":"e_1_3_1_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/0882-4010(90)90077-4"},{"key":"e_1_3_1_38_2","doi-asserted-by":"publisher","unstructured":"Vazquez-Torres A Jones-Carson J Mastroeni P Ischiropoulos H Fang FC. 2000. Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis:227\u2013236. doi:10.1084\/jem.192.2.227","DOI":"10.1084\/jem.192.2.227"},{"key":"e_1_3_1_39_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.287.5458.1655"},{"key":"e_1_3_1_40_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003070"},{"key":"e_1_3_1_41_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.0060074"},{"key":"e_1_3_1_42_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.0040349"},{"key":"e_1_3_1_43_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004359"},{"key":"e_1_3_1_44_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2567.2006.02527.x"},{"key":"e_1_3_1_45_2","doi-asserted-by":"publisher","DOI":"10.1111\/imm.13000"},{"key":"e_1_3_1_46_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2567.2006.02416.x"},{"key":"e_1_3_1_47_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.61.9.3981-3984.1993"},{"key":"e_1_3_1_48_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI33998"},{"key":"e_1_3_1_49_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiu045"},{"key":"e_1_3_1_50_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0910497107"},{"key":"e_1_3_1_51_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ295"},{"key":"e_1_3_1_52_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01423-15"},{"key":"e_1_3_1_53_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.156.9.3321"},{"key":"e_1_3_1_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410x(92)90159-h"},{"key":"e_1_3_1_55_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.65.4.1566-1569.1997"},{"key":"e_1_3_1_56_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23061451"},{"key":"e_1_3_1_57_2","doi-asserted-by":"publisher","DOI":"10.1517\/17460441.2011.609554"},{"key":"e_1_3_1_58_2","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2023.2299384"},{"key":"e_1_3_1_59_2","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00023-16"},{"key":"e_1_3_1_60_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.715393"},{"key":"e_1_3_1_61_2","doi-asserted-by":"publisher","DOI":"10.1128\/br.38.4.371-402.1974"},{"key":"e_1_3_1_62_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32149-9"},{"key":"e_1_3_1_63_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1905047"},{"key":"e_1_3_1_64_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200104263441701"},{"key":"e_1_3_1_65_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400034677"},{"key":"e_1_3_1_66_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1807655115"},{"key":"e_1_3_1_67_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.03079-14"},{"key":"e_1_3_1_68_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00547-15"},{"key":"e_1_3_1_69_2","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410X(95)00249-Z"},{"key":"e_1_3_1_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/0882-4010(87)90019-2"},{"key":"e_1_3_1_71_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.61.4.1211-1221.1993"},{"key":"e_1_3_1_72_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.57.10.3159-3164.1989"},{"key":"e_1_3_1_73_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.73.6.3367-3374.2005"},{"key":"e_1_3_1_74_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01571-06"},{"key":"e_1_3_1_75_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197009242831306"},{"key":"e_1_3_1_76_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01265-10"},{"key":"e_1_3_1_77_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.9.4418-4425.2005"},{"key":"e_1_3_1_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/0882-4010(89)90086-7"},{"key":"e_1_3_1_79_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1111413109"},{"key":"e_1_3_1_80_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep01043"},{"key":"e_1_3_1_81_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1989.tb00957.x"},{"key":"e_1_3_1_82_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0812431106"},{"key":"e_1_3_1_83_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1700952"},{"key":"e_1_3_1_84_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-14655-9"},{"key":"e_1_3_1_85_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1900624"},{"key":"e_1_3_1_86_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.55.3.822-824.1987"},{"key":"e_1_3_1_87_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1302526"},{"key":"e_1_3_1_88_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.25.3.863-872.1979"},{"key":"e_1_3_1_89_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.25.3.857-862.1979"},{"key":"e_1_3_1_90_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1180346"},{"key":"e_1_3_1_91_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiae641"},{"key":"e_1_3_1_92_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0803706"},{"key":"e_1_3_1_93_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1001431"},{"key":"e_1_3_1_94_2","doi-asserted-by":"publisher","DOI":"10.4172\/2157-7560.1000322"},{"key":"e_1_3_1_95_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2567.2011.03411.x"},{"key":"e_1_3_1_96_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004604"},{"key":"e_1_3_1_97_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/131.5.553"},{"key":"e_1_3_1_98_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.4.6.663-673.1971"},{"key":"e_1_3_1_99_2","doi-asserted-by":"publisher","DOI":"10.1086\/518141"},{"key":"e_1_3_1_100_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.07.051"},{"key":"e_1_3_1_101_2","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00058-12"},{"key":"e_1_3_1_102_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.10.002"},{"key":"e_1_3_1_103_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.316.7125.110"},{"key":"e_1_3_1_104_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2007.08.027"},{"key":"e_1_3_1_105_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(18)30087-2"},{"key":"e_1_3_1_106_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)01124-7"},{"key":"e_1_3_1_107_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2035916"},{"key":"e_1_3_1_108_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(21)00255-2"},{"key":"e_1_3_1_109_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2005857117"},{"key":"e_1_3_1_110_2","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines12111272"},{"key":"e_1_3_1_111_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)00249-6"},{"key":"e_1_3_1_112_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.02379-17"},{"key":"e_1_3_1_113_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2023-072938"},{"key":"e_1_3_1_114_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2025.105903"},{"key":"e_1_3_1_115_2","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23071749"},{"key":"e_1_3_1_116_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-025-04003-z"},{"key":"e_1_3_1_117_2","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines11111671"},{"key":"e_1_3_1_118_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40259-023-00627-0"},{"key":"e_1_3_1_119_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00699-20"},{"key":"e_1_3_1_120_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2020.101433"},{"key":"e_1_3_1_121_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2023.11.034"},{"key":"e_1_3_1_122_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1473064"},{"key":"e_1_3_1_123_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2017.03.011"},{"key":"e_1_3_1_124_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jim.2019.04.012"},{"key":"e_1_3_1_125_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2023.120920"},{"key":"e_1_3_1_126_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2024.1347813"},{"key":"e_1_3_1_127_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2013.02.006"},{"key":"e_1_3_1_128_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biologicals.2018.09.001"},{"key":"e_1_3_1_129_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1466869"},{"key":"e_1_3_1_130_2","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00786-13"},{"key":"e_1_3_1_131_2","doi-asserted-by":"publisher","DOI":"10.3390\/mps5060100"},{"key":"e_1_3_1_132_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1443137"},{"key":"e_1_3_1_133_2","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines13020122"},{"key":"e_1_3_1_134_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1610067"},{"key":"e_1_3_1_135_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201343529"},{"key":"e_1_3_1_136_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12977-017-0380-3"},{"key":"e_1_3_1_137_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20201116"},{"key":"e_1_3_1_138_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2019.03.003"},{"key":"e_1_3_1_139_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.00398"},{"key":"e_1_3_1_140_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2010.11.006"},{"key":"e_1_3_1_141_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2006.10.040"},{"key":"e_1_3_1_142_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1190339"},{"key":"e_1_3_1_143_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix042"},{"key":"e_1_3_1_144_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2023-076477"},{"key":"e_1_3_1_145_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0008783"},{"key":"e_1_3_1_146_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy670"}],"container-title":["Infection and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/iai.00118-25","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/iai.00118-25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T14:01:43Z","timestamp":1770732103000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/iai.00118-25"}},"subtitle":[],"editor":[{"given":"Karen M.","family":"Ottemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,2,10]]},"references-count":145,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2,10]]}},"alternative-id":["10.1128\/iai.00118-25"],"URL":"https:\/\/doi.org\/10.1128\/iai.00118-25","relation":{},"ISSN":["0019-9567","1098-5522"],"issn-type":[{"value":"0019-9567","type":"print"},{"value":"1098-5522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,10]]},"assertion":[{"value":"2026-01-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00118-25"}}