{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:48:31Z","timestamp":1790700511279,"version":"4.1.0"},"reference-count":45,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T00:00:00Z","timestamp":1589932800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T00:00:00Z","timestamp":1589932800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP-81301"],"award-info":[{"award-number":["MOP-81301"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["PJT-153285"],"award-info":[{"award-number":["PJT-153285"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Gouvernement du Canada | Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP-110988"],"award-info":[{"award-number":["MOP-110988"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Infect Immun"],"published-print":{"date-parts":[[2020,5,20]]},"abstract":"<jats:p><jats:named-content content-type=\"genus-species\">Pseudomonas aeruginosa<\/jats:named-content>is an opportunistic pathogen that causes chronic and life-threatening infections in immunocompromised patients. A better understanding of the role that innate immunity plays in the control of<jats:named-content content-type=\"genus-species\">P. aeruginosa<\/jats:named-content>infection is crucial for therapeutic development. Specifically, the role of unconventional immune cells like \u03b3\u03b4 T cells in the clearance of<jats:named-content content-type=\"genus-species\">P. aeruginosa<\/jats:named-content>lung infection is not yet well characterized.<\/jats:p>","DOI":"10.1128\/iai.00171-20","type":"journal-article","created":{"date-parts":[[2020,3,30]],"date-time":"2020-03-30T14:20:32Z","timestamp":1585578032000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":20,"title":["Mice Lacking \u03b3\u03b4 T Cells Exhibit Impaired Clearance of Pseudomonas aeruginosa Lung Infection and Excessive Production of Inflammatory Cytokines"],"prefix":"10.1128","volume":"88","author":[{"given":"Toka","family":"Omar","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Ziltener","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin","family":"Chamberlain","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7240-9126","authenticated-orcid":false,"given":"Zhenyu","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5456-2824","authenticated-orcid":false,"given":"Brent","family":"Johnston","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada"},{"name":"Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada"},{"name":"Department of Pathology, Dalhousie University, Halifax, Nova Scotia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","unstructured":"Reference deleted."},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-2920.2011.02469.x"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pupt.2007.12.001"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.15.2.194-222.2002"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2310002"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200302-303OC"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00501-09"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.7.4945"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2014.120"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.1010550"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0004891"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.8.5481"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.7.4662"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200737216"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2172-13-38"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.7.4289-4296.2000"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00312.2006"},{"key":"e_1_3_3_19_2","first-page":"809","article-title":"Role of interleukin-17 in defense against Pseudomonas aeruginosa infection in lungs","volume":"7","author":"Xu X","year":"2014","unstructured":"Xu X, Shao B, Wang R, Zhou S, Tang Z, Lu W, Xiong S. 2014. Role of interleukin-17 in defense against Pseudomonas aeruginosa infection in lungs. Int J Clin Exp Med 7:809\u2013816.","journal-title":"Int J Clin Exp Med"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-016-2387-9"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M402111200"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2005-0246OC"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.2010.00764.x"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2008.03.006"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jir266"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.177.2.475"},{"key":"e_1_3_3_27_2","doi-asserted-by":"crossref","first-page":"275","DOI":"10.4049\/jimmunol.155.1.275","article-title":"Two waves of \u03b3\u03b4 T cells expressing different V \u03b4 genes are recruited into schistosome-induced liver granulomas","volume":"155","author":"Sandor M","year":"1995","unstructured":"Sandor M, Sperling AI, Cook GA, Weinstock JV, Lynch RG, Bluestone JA. 1995. Two waves of \u03b3\u03b4 T cells expressing different V \u03b4 genes are recruited into schistosome-induced liver granulomas. J Immunol 155:275\u2013284.","journal-title":"J Immunol"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1002300"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2014.12.017"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1177\/1753425916668244"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2008.04.022"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1111\/2049-632X.12043"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00717-16"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2011.01.016"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.74.5.2578-2586.2006"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.66.7.3164-3169.1998"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2016.07.052"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm0602-588"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2006.07.016"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI117676"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI121486"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3800"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1999.276.5.L715"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1038\/srep36924"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90112-4"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.278.5343.1623"}],"container-title":["Infection and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/IAI.00171-20","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/IAI.00171-20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T08:28:01Z","timestamp":1695976081000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/IAI.00171-20"}},"subtitle":[],"editor":[{"given":"Marvin","family":"Whiteley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,5,20]]},"references-count":45,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,5,20]]}},"alternative-id":["10.1128\/IAI.00171-20"],"URL":"https:\/\/doi.org\/10.1128\/iai.00171-20","relation":{},"ISSN":["0019-9567","1098-5522"],"issn-type":[{"value":"0019-9567","type":"print"},{"value":"1098-5522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,20]]},"assertion":[{"value":"2020-03-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00171-20"}}