{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T04:24:52Z","timestamp":1793334292651,"version":"4.5.0"},"reference-count":39,"publisher":"American Society for Microbiology","issue":"1","license":[{"start":{"date-parts":[[2020,12,15]],"date-time":"2020-12-15T00:00:00Z","timestamp":1607990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["1R21AI115203"],"award-info":[{"award-number":["1R21AI115203"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Infect Immun"],"published-print":{"date-parts":[[2020,12,15]]},"abstract":"<jats:p>\n            A critical facet of mammalian innate immunity involves the hosts\u2019 attempts to sequester and\/or limit the availability of key metabolic products from pathogens. For example, nutritional immunity encompasses host approaches to limit the availability of key heavy metal ions such as zinc and iron. Previously, we identified several hundred genes in a multidrug-resistant isolate of\n            <jats:named-content content-type=\"genus-species\">Acinetobacter baumannii<\/jats:named-content>\n            that are required for growth and\/or survival in the\n            <jats:named-content content-type=\"genus-species\">Galleria mellonella<\/jats:named-content>\n            infection model.\n          <\/jats:p>","DOI":"10.1128\/iai.00180-20","type":"journal-article","created":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T14:03:53Z","timestamp":1602857033000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":18,"title":["GigC, a LysR Family Transcription Regulator, Is Required for Cysteine Metabolism and Virulence in Acinetobacter baumannii"],"prefix":"10.1128","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1213-8408","authenticated-orcid":false,"given":"Michael J.","family":"Gebhardt","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Boston Children\u2019s Hospital, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7491-5292","authenticated-orcid":false,"given":"Daniel M.","family":"Czyz","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Cell Science, University of Florida, Gainesville, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shweta","family":"Singh","sequence":"additional","affiliation":[{"name":"Wound Infections Dept., Bacterial Diseases Branch, Center for Infectious Diseases Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7920-5601","authenticated-orcid":false,"given":"Daniel V.","family":"Zurawski","sequence":"additional","affiliation":[{"name":"Wound Infections Dept., Bacterial Diseases Branch, Center for Infectious Diseases Research, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9663-8038","authenticated-orcid":false,"given":"Lev","family":"Becker","sequence":"additional","affiliation":[{"name":"Ben May Department of Cancer Research, University of Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7955-8709","authenticated-orcid":false,"given":"Howard A.","family":"Shuman","sequence":"additional","affiliation":[{"name":"Department of Microbiology, University of Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00058-16"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2012.00148"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/gbe\/evu225"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/2049-632X.12125"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00315-10"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1377"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2009.08.003"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01660-15"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01163-14"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00013-15"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.2174\/0929867321666141112122553"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01076-14"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002030100298"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2006.00036.x"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2015.01.058"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.2008\/022772-0"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.2174\/0929866033478942"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2011.07919.x"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.3791\/51809"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1101\/pdb.prot5414"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.39.6.853"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.179.24.7671-7678.1997"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky752"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1209855"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm800571m"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm900728u"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm901325e"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2007.09.009"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.9b00406"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/0076-6879(87)43065-6"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.177.1.1-10.1995"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.148.2.639-646.1981"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055594"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055593"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01578-08"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1119(87)90095-3"},{"key":"e_1_3_3_38_2","volume-title":"Experiments in molecular genetics","author":"Miller JH","year":"1972","unstructured":"Miller JH. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY."},{"key":"e_1_3_3_39_2","volume-title":"Guide for the care and use of laboratory animals","author":"National Research Council","year":"2011","unstructured":"National Research Council. 2011. Guide for the care and use of laboratory animals, 8th ed. National Academies Press, Washington, DC. https:\/\/doi.org\/10.17226\/12910.","edition":"8"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2009.09.004"}],"container-title":["Infection and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/IAI.00180-20","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/IAI.00180-20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T11:54:14Z","timestamp":1646481254000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/IAI.00180-20"}},"subtitle":[],"editor":[{"given":"Igor E.","family":"Brodsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,12,15]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,12,15]]}},"alternative-id":["10.1128\/IAI.00180-20"],"URL":"https:\/\/doi.org\/10.1128\/iai.00180-20","relation":{},"ISSN":["0019-9567","1098-5522"],"issn-type":[{"value":"0019-9567","type":"print"},{"value":"1098-5522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,15]]},"assertion":[{"value":"2020-03-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00180-20"}}