{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T23:53:40Z","timestamp":1790380420235,"version":"4.1.0"},"reference-count":60,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T00:00:00Z","timestamp":1595289600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["AI121752"],"award-info":[{"award-number":["AI121752"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["AI130059"],"award-info":[{"award-number":["AI130059"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Infect Immun"],"published-print":{"date-parts":[[2020,7,21]]},"abstract":"<jats:p>\n            <jats:italic>Chlamydia<\/jats:italic>\n            bacteria are obligate intracellular pathogens which can cause a variety of disease in humans and other vertebrate animals. To successfully complete its life cycle,\n            <jats:italic>Chlamydia<\/jats:italic>\n            must evade both intracellular innate immune responses and adaptive cytotoxic T cell responses. Here, we report on the role of the chlamydial lipooligosaccharide (LOS) in evading the immune response.\n            <jats:italic>Chlamydia<\/jats:italic>\n            infection is known to block the induction of apoptosis. However, when LOS synthesis was inhibited during\n            <jats:named-content content-type=\"genus-species\">Chlamydia trachomatis<\/jats:named-content>\n            infection, HeLa cells regained susceptibility to apoptosis induction following staurosporine treatment.\n          <\/jats:p>","DOI":"10.1128\/iai.00198-20","type":"journal-article","created":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T13:24:34Z","timestamp":1589808274000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":12,"title":["<i>Chlamydia<\/i>\n            Lipooligosaccharide Has Varied Direct and Indirect Roles in Evading both Innate and Adaptive Host Immune Responses"],"prefix":"10.1128","volume":"88","author":[{"given":"Xisheng","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences, Carlson College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel D.","family":"Rockey","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Carlson College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5985-1887","authenticated-orcid":false,"given":"Brian P.","family":"Dolan","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Carlson College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1865-1682.2011.01274.x"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1086\/652401"},{"key":"e_1_3_2_4_2","first-page":"844","article-title":"Global data on visual impairment in the year 2002","volume":"82","author":"Resnikoff S","year":"2004","unstructured":"Resnikoff S, Pascolini D, Etya'ale D, Kocur I, Pararajasegaram R, Pokharel GP, Mariotti SP. 2004. 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