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Some of these pathogens also have a tropism for the reproductive system, thereby increasing the risk of reproductive disease and infertility. To date, the pathogenic mechanism involved remains poorly understood. Here, we demonstrate that<jats:named-content content-type=\"genus-species\">Brucella abortus<\/jats:named-content>, a notorious reproductive pathogen, has the ability to infect the nonpregnant uterus, sustain infection, and induce inflammatory changes during both acute and chronic stages of infection.<\/jats:p>","DOI":"10.1128\/iai.00257-20","type":"journal-article","created":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T14:56:41Z","timestamp":1594997801000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":11,"title":["Brucella abortus and Pregnancy in Mice: Impact of Chronic Infection on Fertility and the Role of Regulatory T Cells in Tissue Colonization"],"prefix":"10.1128","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5352-3695","authenticated-orcid":false,"given":"Shakirat A.","family":"Adetunji","sequence":"first","affiliation":[{"name":"Department of Veterinary Pathobiology, Texas A&amp;M University, College Station, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise L.","family":"Faustman","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. 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