{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T13:37:17Z","timestamp":1780925837118,"version":"3.54.1"},"reference-count":125,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T00:00:00Z","timestamp":1676505600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T00:00:00Z","timestamp":1676505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["01KI1726C"],"award-info":[{"award-number":["01KI1726C"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["01KI1726C"],"award-info":[{"award-number":["01KI1726C"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Infect Immun"],"published-print":{"date-parts":[[2023,2,16]]},"abstract":"<jats:p>\n            Dendritic cells (DCs) belong to the first line of innate defense and come into early contact with invading pathogens, including the zoonotic bacterium\n            <jats:named-content content-type=\"genus-species\">Coxiella burnetii<\/jats:named-content>\n            , the causative agent of Q fever. However, the pathogen-host cell interactions in\n            <jats:named-content content-type=\"genus-species\">C. burnetii<\/jats:named-content>\n            -infected DCs, particularly the role of mechanisms of immune subversion beyond virulent phase I lipopolysaccharide (LPS), as well as the contribution of cellular self-defense strategies, are not understood.\n          <\/jats:p>","DOI":"10.1128\/iai.00323-22","type":"journal-article","created":{"date-parts":[[2023,1,23]],"date-time":"2023-01-23T14:01:46Z","timestamp":1674482506000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":7,"title":["TGF-\u03b2\/IFN-\u03b3 Antagonism in Subversion and Self-Defense of Phase II Coxiella burnetii\n            <i>-<\/i>\n            Infected Dendritic Cells"],"prefix":"10.1128","volume":"91","author":[{"given":"Svea","family":"Matthiesen","sequence":"first","affiliation":[{"name":"Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Isle of Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahne","family":"Christiansen","sequence":"additional","affiliation":[{"name":"Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Isle of Riems, Germany"},{"name":"Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Isle of Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rico","family":"Jahnke","sequence":"additional","affiliation":[{"name":"Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Isle of Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca M.","family":"Zaeck","sequence":"additional","affiliation":[{"name":"Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Isle of Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0054-7394","authenticated-orcid":true,"given":"Axel","family":"Karger","sequence":"additional","affiliation":[{"name":"Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Isle of Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Finke","sequence":"additional","affiliation":[{"name":"Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Isle of Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kati","family":"Franzke","sequence":"additional","affiliation":[{"name":"Institute of Infectology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Isle of Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1603-9861","authenticated-orcid":true,"given":"Michael R.","family":"Knittler","sequence":"additional","affiliation":[{"name":"Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Isle of Riems, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri1246"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2172-12-52"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2006.09.003"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni1001-907"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.56.7.1792-1799.1988"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00045-16"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.12.4.518"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1089\/15303660260613747"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.4161\/auto.2827"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1139\/m56-036"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.170.3.1227-1234.1988"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00406-10"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a120370"},{"key":"e_1_3_3_15_2","first-page":"703","article-title":"Experience in mass immunization of humans with the M-44 live vaccine against Q-fever. 2. Skin and oral routes of immunization","volume":"10","author":"Genig VA","year":"1965","unstructured":"Genig VA. 1965. Experience in mass immunization of humans with the M-44 live vaccine against Q-fever. 2. Skin and oral routes of immunization. Vopr Virusol 10:703\u2013707.","journal-title":"Vopr Virusol"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/am.27.4.777-783.1974"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.754690"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.22.4.484-487.1985"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-015-2143-7"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01767-06"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.12.8372"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.45.3.781-783.1984"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200738067"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0501863102"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M410340200"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01208-15"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.077230-0"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10205"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01536-15"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00532-18"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiq037"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2021.754455"},{"key":"e_1_3_3_33_2","unstructured":"MacKay VL Moore EE. 15 July 1997. Immortalized dendritic cells. US Patent 5 648 219."},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)61258-X"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00172-20"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1202741"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.162.8.4567"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1286-4579(99)00252-x"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1600244"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri1685"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-04142-5"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V76.12.2466.2466"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.174821"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.imlet.2006.02.003"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19123805"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-065X.2000.917307.x"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2014.01.016"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M706909200"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01584-07"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2011.04.029"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.10.5816-5821.2002"},{"key":"e_1_3_3_52_2","first-page":"3","article-title":"Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles","volume":"66","author":"Biederbick A","year":"1995","unstructured":"Biederbick A, Kern HF, Elsasser HP. 1995. Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles. Eur J Cell Biol 66:3\u201314.","journal-title":"Eur J Cell Biol"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1286-4579(03)00096-0"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0005-2728(99)00025-0"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-03-419747"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines6020056"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-0333"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a022236"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000066"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00078-15"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.64.10.4143-4147.1996"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1093\/genetics\/iyab005"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.71.5.845"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01541176"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.00-0508hyp"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a005017"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2015.06.010"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2016.94"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0010850"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1355.025"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00901-07"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004286"},{"key":"e_1_3_3_73_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004013"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12432"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00175-11"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1309195110"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006101"},{"key":"e_1_3_3_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cimid.2017.03.004"},{"key":"e_1_3_3_79_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI65859"},{"key":"e_1_3_3_80_2","doi-asserted-by":"publisher","DOI":"10.1515\/bmc-2020-0006"},{"key":"e_1_3_3_81_2","doi-asserted-by":"publisher","DOI":"10.1093\/jb\/mvq043"},{"key":"e_1_3_3_82_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.00-0233com"},{"key":"e_1_3_3_83_2","doi-asserted-by":"publisher","DOI":"10.1038\/17826"},{"key":"e_1_3_3_84_2","doi-asserted-by":"publisher","DOI":"10.1080\/08830180902978120"},{"key":"e_1_3_3_85_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2567.2003.01620.x"},{"key":"e_1_3_3_86_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.7.4461"},{"key":"e_1_3_3_87_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.173.3.1514"},{"key":"e_1_3_3_88_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00602-17"},{"key":"e_1_3_3_89_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2017.07.008"},{"key":"e_1_3_3_90_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.9.5140-5147.2002"},{"key":"e_1_3_3_91_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.3.1225-1233.2003"},{"key":"e_1_3_3_92_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.72.11.6666-6675.2004"},{"key":"e_1_3_3_93_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.05.035"},{"key":"e_1_3_3_94_2","doi-asserted-by":"publisher","DOI":"10.1111\/all.12172"},{"key":"e_1_3_3_95_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri1186"},{"key":"e_1_3_3_96_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201041022"},{"key":"e_1_3_3_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(03)00171-7"},{"key":"e_1_3_3_98_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00881-06"},{"key":"e_1_3_3_99_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V71.6.1590.1590"},{"key":"e_1_3_3_100_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007955"},{"key":"e_1_3_3_101_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.67.7.3236-3241.1999"},{"key":"e_1_3_3_102_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.imlet.2006.05.008"},{"key":"e_1_3_3_103_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2004.06.061"},{"key":"e_1_3_3_104_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi060143j"},{"key":"e_1_3_3_105_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.046649-0"},{"key":"e_1_3_3_106_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.22.10359"},{"key":"e_1_3_3_107_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.178.2.605"},{"key":"e_1_3_3_108_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.155.4.2077"},{"key":"e_1_3_3_109_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3024.2002.00444.x"},{"key":"e_1_3_3_110_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-8-98"},{"key":"e_1_3_3_111_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2011.00084"},{"key":"e_1_3_3_112_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.186.14.4655-4664.2004"},{"key":"e_1_3_3_113_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2006.05290.x"},{"key":"e_1_3_3_114_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbabio.2011.06.016"},{"key":"e_1_3_3_115_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2006.00838.x"},{"key":"e_1_3_3_116_2","doi-asserted-by":"publisher","DOI":"10.1111\/cas.13945"},{"key":"e_1_3_3_117_2","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2014.264"},{"key":"e_1_3_3_118_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00881-12"},{"key":"e_1_3_3_119_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01487-05"},{"key":"e_1_3_3_120_2","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.201700251"},{"key":"e_1_3_3_121_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaa1100"},{"key":"e_1_3_3_122_2","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12494"},{"key":"e_1_3_3_123_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1231143"},{"key":"e_1_3_3_124_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-19626-1"},{"key":"e_1_3_3_125_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2019"},{"key":"e_1_3_3_126_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.17.8103"}],"container-title":["Infection and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/iai.00323-22","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/iai.00323-22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T14:01:24Z","timestamp":1676556084000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/iai.00323-22"}},"subtitle":[],"editor":[{"given":"Craig R.","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,2,16]]},"references-count":125,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2,16]]}},"alternative-id":["10.1128\/iai.00323-22"],"URL":"https:\/\/doi.org\/10.1128\/iai.00323-22","relation":{},"ISSN":["0019-9567","1098-5522"],"issn-type":[{"value":"0019-9567","type":"print"},{"value":"1098-5522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,16]]},"assertion":[{"value":"2022-07-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00323-22"}}