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The twin-arginine translocation (Tat) pathway transports folded proteins across the cytoplasmic membrane and has been implicated in virulence in many bacterial pathogens. However, the roles of the Tat system and related substrates in\n            <jats:italic>Brucella<\/jats:italic>\n            remain unclear. We report here that disruption of Tat increases the sensitivity of\n            <jats:named-content content-type=\"genus-species\">Brucella melitensis<\/jats:named-content>\n            M28 to the membrane stressor sodium dodecyl sulfate (SDS), indicating cell envelope defects, as well as to EDTA.\n          <\/jats:p>","DOI":"10.1128\/iai.00389-20","type":"journal-article","created":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T12:46:55Z","timestamp":1596804415000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":19,"title":["The Twin-Arginine Translocation System Is Important for Stress Resistance and Virulence of Brucella melitensis"],"prefix":"10.1128","volume":"88","author":[{"given":"Xin","family":"Yan","sequence":"first","affiliation":[{"name":"Key Laboratory of Veterinary Public Health of Ministry of Agriculture, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, 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