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Multiple bacterial factors are known to contribute to persistent colonization of this niche, and many are important in mucosal immunity and vaccine development. In this work, mice were infected intranasally with transcriptional regulator mutants of the Rgg2\/3 quorum sensing (QS) system\u2014a peptide-based signaling system conserved in sequenced isolates of\n                    <jats:named-content content-type=\"genus-species\">S. pyogenes<\/jats:named-content>\n                    .\n                  <\/jats:p>","DOI":"10.1128\/iai.00464-20","type":"journal-article","created":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T09:38:43Z","timestamp":1596533923000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":19,"title":["Colonization of the Murine Oropharynx by Streptococcus pyogenes Is Governed by the Rgg2\/3 Quorum Sensing System"],"prefix":"10.1128","volume":"88","author":[{"given":"Artemis","family":"Gogos","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology, University of Illinois at Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Federle","sequence":"additional","affiliation":[{"name":"Center for Biomolecular Sciences, Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(05)70267-X"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01560-08"},{"key":"e_1_3_3_4_2","volume-title":"Streptococcus pyogenes: basic biology to clinical manifestations","author":"Wessels MR","year":"2016","unstructured":"Wessels MR. 2016. 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