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To better understand the mechanisms associated with\n                    <jats:italic>Chlamydia<\/jats:italic>\n                    -induced genital tract pathogenesis in humans, we used CRISPR genome editing to disrupt Toll-like receptor 3 (TLR3) function in the human oviduct epithelial (hOE) cell line OE-E6\/E7 in order to investigate the possible role(s) of TLR3 signaling in the immune response to\n                    <jats:italic>Chlamydia<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1128\/iai.00483-19","type":"journal-article","created":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T09:25:07Z","timestamp":1564651507000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":12,"title":["Toll-Like Receptor 3 Deficiency Leads to Altered Immune Responses to Chlamydia trachomatis Infection in Human Oviduct Epithelial Cells"],"prefix":"10.1128","volume":"87","author":[{"given":"Jerry Z.","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramesh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoli","family":"Gong","sequence":"additional","affiliation":[{"name":"Xiangya Second Hospital, Central South University, Changsha, Hunan Province, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luyao","family":"Liu","sequence":"additional","affiliation":[{"name":"Xiangya Second Hospital, Central South University, Changsha, Hunan Province, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Ramos-Solis","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8250-6261","authenticated-orcid":false,"given":"Wilbert A.","family":"Derbigny","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","volume-title":"2015 sexually transmitted diseases survey","author":"CDC","year":"2017","unstructured":"CDC. 2017. 2015 sexually transmitted diseases survey. 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