{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T09:02:48Z","timestamp":1790413368469,"version":"4.1.0"},"reference-count":59,"publisher":"American Society for Microbiology","issue":"12","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"name":"Michelson Medical Research Foundation","award":["n\/a"],"award-info":[{"award-number":["n\/a"]}]},{"name":"Baylor College of Medicine Pathology and Histology Cancer Center","award":["P30 CA125123"],"award-info":[{"award-number":["P30 CA125123"]}]},{"name":"Veterans Affairs office of research and development","award":["1I01BX002221"],"award-info":[{"award-number":["1I01BX002221"]}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["R01 HL117181"],"award-info":[{"award-number":["R01 HL117181"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"DH | National Institute for Health Research","doi-asserted-by":"publisher","award":["T32 AI055413"],"award-info":[{"award-number":["T32 AI055413"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Infect Immun"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:p>\n                    <jats:named-content content-type=\"genus-species\">Ascaris lumbricoides<\/jats:named-content>\n                    (roundworm) is the most common helminth infection globally and a cause of lifelong morbidity that may include allergic airway disease, an asthma phenotype. We hypothesize that\n                    <jats:italic>Ascaris<\/jats:italic>\n                    larval migration through the lungs leads to persistent airway hyperresponsiveness (AHR) and type 2 inflammatory lung pathology despite resolution of infection that resembles allergic airway disease.\n                  <\/jats:p>","DOI":"10.1128\/iai.00533-18","type":"journal-article","created":{"date-parts":[[2018,9,19]],"date-time":"2018-09-19T07:13:36Z","timestamp":1537341216000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":43,"title":["<i>Ascaris<\/i>\n                    Larval Infection and Lung Invasion Directly Induce Severe Allergic Airway Disease in Mice"],"prefix":"10.1128","volume":"86","author":[{"given":"Jill E.","family":"Weatherhead","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA"},{"name":"Department of Medicine, Baylor College of Medicine, Houston, Texas, USA"},{"name":"National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Porter","sequence":"additional","affiliation":[{"name":"Department of Medicine, Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Coffey","sequence":"additional","affiliation":[{"name":"Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Haydel","sequence":"additional","affiliation":[{"name":"Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leroy","family":"Versteeg","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Zhan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA"},{"name":"National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Clara","family":"Gazzinelli Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"Departamento de Parasitologia, Federal University of Minas Gerais, Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Fujiwara","sequence":"additional","affiliation":[{"name":"Departamento de Parasitologia, Federal University of Minas Gerais, Minas Gerais, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana M.","family":"Jaramillo","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Elena","family":"Bottazzi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA"},{"name":"National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, USA"},{"name":"Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA"},{"name":"Texas Children\u2019s Hospital Center for Vaccine Development-Product Development Partnership, Houston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Hotez","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA"},{"name":"National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, USA"},{"name":"Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA"},{"name":"Texas Children\u2019s Hospital Center for Vaccine Development-Product Development Partnership, Houston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David B.","family":"Corry","sequence":"additional","affiliation":[{"name":"Department of Medicine, Baylor College of Medicine, Houston, Texas, USA"},{"name":"Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA"},{"name":"Biology of Inflammation Center, Baylor College of Medicine, Houston, Texas, USA"},{"name":"Michael E. DeBakey Center for Translational Research in Inflammatory Diseases, Houston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coreen M.","family":"Beaumier","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA"},{"name":"Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31678-6"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/1756-3305-7-37"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1542\/pir.36-8-341"},{"key":"e_1_3_2_5_2","first-page":"467","volume-title":"Disease control priorities in developing countries","author":"Hotez PJ","year":"2006","unstructured":"Hotez PJ, Bundy DAP, Beegle K, Brooker S, Drake L, de Silva N, Montresor A, Engels D, Jukes M, Chitsulo L, Chow J, Laxminarayan R, Michaud C, Bethony J, Correa-Oliveira R, Shuhua X, Fenwick A, Savioli L. 2006. Helminth infections: soil-transmitted helminth infections and schistosomiasis, p 467\u2013482. In Jamison DT, Breman JG, Measham AR, Alleyne G, Claeson M, Evans DB, Jha P, Mills A, Musgrove P (ed), Disease control priorities in developing countries, 2nd ed. Oxford University Press, New York, NY.","edition":"2"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31012-1"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-0262.2004.00481.x"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00025-12"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/29.12.1372"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004944"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200603-331OC"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1967.16.646"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40413-015-0058-z"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.alit.2015.07.002"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20833"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2007.06.010"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2017.12.007"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2628"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2014.06.003"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12026-011-8258-2"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/380627a0"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80477-X"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2172-10-58"},{"key":"e_1_3_2_24_2","volume-title":"The global asthma report 2014","author":"Marks G","year":"2014","unstructured":"Marks G, Pearch N, Strachan IAD. 2014. The global asthma report 2014. Global Asthma Network, Auckland, New Zealand."},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2009.102"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1240342"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2015.01.005"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.2149\/tmh.2013-19"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2015.05.010"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-6786-5_12"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/cea.12880"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200808-089RM"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1111\/pim.12194"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1097\/ACI.0000000000000227"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2016.04.022"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.3791\/1720"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2107020"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40475-015-0058-7"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1177\/039463200601900319"},{"key":"e_1_3_2_40_2","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/796820"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2018.07.016"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2010.12.001"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2018.1424543"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2017.09.005"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004382"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1254\/jjp.27.285"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2007.02.009"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiw027"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2011.10.043"},{"key":"e_1_3_2_50_2","doi-asserted-by":"publisher","DOI":"10.1586\/eri.11.92"},{"key":"e_1_3_2_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2010.09.006"},{"key":"e_1_3_2_52_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2005.02250.x"},{"key":"e_1_3_2_53_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00012-07"},{"key":"e_1_3_2_54_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2014.09.008"},{"key":"e_1_3_2_55_2","doi-asserted-by":"publisher","DOI":"10.1111\/resp.12078"},{"key":"e_1_3_2_56_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0092307"},{"key":"e_1_3_2_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2013.02.009"},{"key":"e_1_3_2_58_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182007002582"},{"key":"e_1_3_2_59_2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00593.2002"},{"key":"e_1_3_2_60_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jim.2016.11.003"}],"container-title":["Infection and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/IAI.00533-18","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/IAI.00533-18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T05:42:44Z","timestamp":1646458964000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/IAI.00533-18"}},"subtitle":[],"editor":[{"given":"John H.","family":"Adams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":59,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["10.1128\/IAI.00533-18"],"URL":"https:\/\/doi.org\/10.1128\/iai.00533-18","relation":{},"ISSN":["0019-9567","1098-5522"],"issn-type":[{"value":"0019-9567","type":"print"},{"value":"1098-5522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"2018-07-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00533-18"}}