{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T18:51:13Z","timestamp":1789930273197,"version":"4.0.1"},"reference-count":21,"publisher":"American Society for Microbiology","issue":"8","license":[{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Infect Immun"],"published-print":{"date-parts":[[2006,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            A\n            <jats:italic>Brucella suis<\/jats:italic>\n            mutant with a nonpolar deletion in the\n            <jats:italic>virB8<\/jats:italic>\n            gene was attenuated in a macrophage infection model. Complementation with the\n            <jats:italic>B. suis<\/jats:italic>\n            VirB8 protein expressed from the\n            <jats:italic>virB<\/jats:italic>\n            promoter restored virulence. Expression of TraJ, a VirB8 homologue from plasmid pSB102, did not restore virulence; however, virulence was partially restored by a chimeric protein containing the N terminus of the\n            <jats:italic>B. suis<\/jats:italic>\n            VirB8 protein and the C-terminal periplasmic domain of TraJ.\n          <\/jats:p>","DOI":"10.1128\/iai.00584-06","type":"journal-article","created":{"date-parts":[[2006,7,22]],"date-time":"2006-07-22T00:24:50Z","timestamp":1153527890000},"page":"4945-4949","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":26,"title":["Swapping of Periplasmic Domains between\n            <i>Brucella suis<\/i>\n            VirB8 and a pSB102 VirB8 Homologue Allows Heterologous Complementation"],"prefix":"10.1128","volume":"74","author":[{"given":"Gilles","family":"Patey","sequence":"first","affiliation":[{"name":"Institut National de la Sante\u0301 et de la Recherche Me\u0301dicale U431, UFR Me\u0301decine, CS83021, Avenue Kennedy, 30908 Ni\u0302mes Cedex 02, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhong","family":"Qi","sequence":"additional","affiliation":[{"name":"Institut National de la Sante\u0301 et de la Recherche Me\u0301dicale U431, UFR Me\u0301decine, CS83021, Avenue Kennedy, 30908 Ni\u0302mes Cedex 02, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisele","family":"Bourg","sequence":"additional","affiliation":[{"name":"Institut National de la Sante\u0301 et de la Recherche Me\u0301dicale U431, UFR Me\u0301decine, CS83021, Avenue Kennedy, 30908 Ni\u0302mes Cedex 02, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Baron","sequence":"additional","affiliation":[{"name":"Department of Biology, McMaster University, 1280 Main St. West, Hamilton, Ontario LS8 4K1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"O'Callaghan","sequence":"additional","affiliation":[{"name":"Institut National de la Sante\u0301 et de la Recherche Me\u0301dicale U431, UFR Me\u0301decine, CS83021, Avenue Kennedy, 30908 Ni\u0302mes Cedex 02, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0511216103"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.032514299"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.74.1.108-117.2006"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro753"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1095211"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.58.030603.123630"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.186.5.1415-1422.2004"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0505290102"},{"key":"e_1_3_2_10_2","first-page":"800","volume":"16","year":"1994","unstructured":"Kovach, M. 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