{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T16:06:50Z","timestamp":1779293210634,"version":"3.51.4"},"reference-count":31,"publisher":"American Society for Microbiology","issue":"12","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["AI119646"],"award-info":[{"award-number":["AI119646"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000069","name":"HHS | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["P50AR072000"],"award-info":[{"award-number":["P50AR072000"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Infect Immun"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:p>\n            Management of foot salvage therapy (FST) for diabetic foot infections (DFI) is challenging due to the absence of reliable diagnostics to identify the etiologic agent and prognostics to justify aggressive treatments. As\n            <jats:named-content content-type=\"genus-species\">Staphylococcus aureus<\/jats:named-content>\n            is the most common pathogen associated with DFI, we aimed to develop a multiplex immunoassay of IgG in serum and medium enriched for newly synthesized anti-\n            <jats:named-content content-type=\"genus-species\">S. aureus<\/jats:named-content>\n            antibodies (MENSA) generated from cultured peripheral blood mononuclear cells of DFI patients undergoing FST.\n          <\/jats:p>","DOI":"10.1128\/iai.00629-18","type":"journal-article","created":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T11:39:31Z","timestamp":1538393971000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":34,"title":["Tracking Anti-\n            <i>Staphylococcus aureus<\/i>\n            Antibodies Produced\n            <i>In Vivo<\/i>\n            and\n            <i>Ex Vivo<\/i>\n            during Foot Salvage Therapy for Diabetic Foot Infections Reveals Prognostic Insights and Evidence of Diversified Humoral Immunity"],"prefix":"10.1128","volume":"86","author":[{"given":"Irvin","family":"Oh","sequence":"first","affiliation":[{"name":"Center for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7521-6154","authenticated-orcid":false,"given":"Gowrishankar","family":"Muthukrishnan","sequence":"additional","affiliation":[{"name":"Center for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark J.","family":"Ninomiya","sequence":"additional","affiliation":[{"name":"Center for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"James D.","family":"Brodell","sequence":"additional","affiliation":[{"name":"Center for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin L.","family":"Smith","sequence":"additional","affiliation":[{"name":"Center for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles C.","family":"Lee","sequence":"additional","affiliation":[{"name":"Center for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven R.","family":"Gill","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher A.","family":"Beck","sequence":"additional","affiliation":[{"name":"Center for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA"},{"name":"Department of Biostatistics and Computational Biology, University of Rochester, Rochester, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward M.","family":"Schwarz","sequence":"additional","affiliation":[{"name":"Center for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA"},{"name":"Department of Microbiology and Immunology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John L.","family":"Daiss","sequence":"additional","affiliation":[{"name":"Center for Musculoskeletal Research and Department of Orthopaedics, University of Rochester Medical Center, Rochester, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1615439"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.3947\/ic.2018.50.1.11"},{"key":"e_1_3_3_4_2","volume-title":"National diabetes statistics report, 2017","author":"Centers for Disease Control and Prevention","year":"2017","unstructured":"Centers for Disease Control and Prevention. 2017. 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