{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T12:51:07Z","timestamp":1791723067151,"version":"4.3.4"},"reference-count":28,"publisher":"American Society for Microbiology","issue":"12","license":[{"start":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T00:00:00Z","timestamp":1164931200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Infect Immun"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The facultative intracellular pathogen\n                    <jats:italic>Salmonella enterica<\/jats:italic>\n                    causes a variety of diseases, including gastroenteritis and typhoid fever. Inside epithelial cells,\n                    <jats:italic>Salmonella<\/jats:italic>\n                    replicates in vacuoles, which localize in the perinuclear area in close proximity to the Golgi apparatus. Among the effector proteins translocated by the\n                    <jats:italic>Salmonella<\/jats:italic>\n                    pathogenicity island 2-encoded type III secretion system, SifA and SseG have been shown necessary but not sufficient to ensure the intracellular positioning of\n                    <jats:italic>Salmonella<\/jats:italic>\n                    vacuoles. Hence, we have investigated the involvement of other secreted effector proteins in this process. Here we show that SseF interacts functionally and physically with SseG but not SifA and is also required for the perinuclear localization of\n                    <jats:italic>Salmonella<\/jats:italic>\n                    vacuoles. The observations show that the intracellular positioning of\n                    <jats:italic>Salmonella<\/jats:italic>\n                    vacuoles is a complex phenomenon resulting from the combined action of several effector proteins.\n                  <\/jats:p>","DOI":"10.1128\/iai.00648-06","type":"journal-article","created":{"date-parts":[[2006,11,20]],"date-time":"2006-11-20T20:05:37Z","timestamp":1164053137000},"page":"6965-6972","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":114,"title":["The Translocated\n                    <i>Salmonella<\/i>\n                    Effector Proteins SseF and SseG Interact and Are Required To Establish an Intracellular Replication Niche"],"prefix":"10.1128","volume":"74","author":[{"given":"Jo\u0308rg","family":"Deiwick","sequence":"first","affiliation":[{"name":"Centre d'Immunologie de Marseille-Luminy, CNRS-INSERM-Universite\u0301 de la Me\u0301diterrane\u0301e, Parc Scientifique de Luminy, Case 906-13288, Marseille Cedex 9, France"},{"name":"Institute of Biochemistry, Center for Structural and Cell Biology in Medicine, University of Lu\u0308beck, Ratzeburger Allee 160, 23538 Lu\u0308beck, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzana P.","family":"Salcedo","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Centre for Molecular Microbiology and Infection, Imperial College London, Armstrong Road, London SW7 2AZ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Boucrot","sequence":"additional","affiliation":[{"name":"Centre d'Immunologie de Marseille-Luminy, CNRS-INSERM-Universite\u0301 de la Me\u0301diterrane\u0301e, Parc Scientifique de Luminy, Case 906-13288, Marseille Cedex 9, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah M.","family":"Gilliland","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Centre for Molecular Microbiology and Infection, Imperial College London, Armstrong Road, London SW7 2AZ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Henry","sequence":"additional","affiliation":[{"name":"Centre d'Immunologie de Marseille-Luminy, CNRS-INSERM-Universite\u0301 de la Me\u0301diterrane\u0301e, Parc Scientifique de Luminy, Case 906-13288, Marseille Cedex 9, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nele","family":"Petermann","sequence":"additional","affiliation":[{"name":"Institute of Biochemistry, Center for Structural and Cell Biology in Medicine, University of Lu\u0308beck, Ratzeburger Allee 160, 23538 Lu\u0308beck, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott R.","family":"Waterman","sequence":"additional","affiliation":[{"name":"Department of 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