{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T14:05:05Z","timestamp":1773065105680,"version":"3.50.1"},"reference-count":46,"publisher":"American Society for Microbiology","issue":"6","license":[{"start":{"date-parts":[[2022,6,16]],"date-time":"2022-06-16T00:00:00Z","timestamp":1655337600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2022,6,16]],"date-time":"2022-06-16T00:00:00Z","timestamp":1655337600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","award":["201706170060"],"award-info":[{"award-number":["201706170060"]}],"id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Infect Immun"],"published-print":{"date-parts":[[2022,6,16]]},"abstract":"<jats:p>Peritonitis and abdominal sepsis remain major health problems and challenge for clinicians. Bruton\u2019s tyrosine kinase (Btk) is a versatile signaling protein involved in the regulation of B cell development and function, as well as innate host defense.<\/jats:p>","DOI":"10.1128\/iai.00674-21","type":"journal-article","created":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T13:01:13Z","timestamp":1652965273000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":1,"title":["Bruton\u2019s Tyrosine Kinase Deficiency Ameliorates Antimicrobial Host Defense during Peritonitis Induced by Pathogenic Escherichia coli"],"prefix":"10.1128","volume":"90","author":[{"given":"Zhe","family":"Liu","sequence":"first","affiliation":[{"name":"Center for Experimental and Molecular Medicine (CEMM), Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Amsterdam Infection and Immunity Institute (AI&amp;II), Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cornelis","family":"van \u2018t Veer","sequence":"additional","affiliation":[{"name":"Center for Experimental and Molecular Medicine (CEMM), Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Amsterdam Infection and Immunity Institute (AI&amp;II), Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudi W.","family":"Hendriks","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joris J. T. H.","family":"Roelofs","sequence":"additional","affiliation":[{"name":"Amsterdam Infection and Immunity Institute (AI&amp;II), Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Department of Pathology, Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"van der Poll","sequence":"additional","affiliation":[{"name":"Center for Experimental and Molecular Medicine (CEMM), Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Amsterdam Infection and Immunity Institute (AI&amp;II), Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Division of Infectious Diseases, Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2472-3014","authenticated-orcid":true,"given":"Alex F.","family":"de Vos","sequence":"additional","affiliation":[{"name":"Center for Experimental and Molecular Medicine (CEMM), Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Amsterdam Infection and Immunity Institute (AI&amp;II), Amsterdam UMC, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.0287"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1312359"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-007-0194-6"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830231210"},{"key":"e_1_3_3_6_2","doi-asserted-by":"crossref","first-page":"557","DOI":"10.4049\/jimmunol.152.2.557","article-title":"Expression of Bruton's agammaglobulinemia tyrosine kinase gene, BTK, is selectively down-regulated in T lymphocytes and plasma cells","volume":"152","author":"Smith CI","year":"1994","unstructured":"Smith CI, Baskin B, Humire-Greiff P, Zhou JN, Olsson PG, Maniar HS, Kjellen P, Lambris JD, Christensson B, Hammarstrom L, et al. 1994. Expression of Bruton's agammaglobulinemia tyrosine kinase gene, BTK, is selectively down-regulated in T lymphocytes and plasma cells. J Immunol 152:557\u2013565.","journal-title":"J Immunol"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1006\/smim.1998.0123"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-065x.2000.17811.x"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1615\/CritRevImmunol.2018025184"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-07-102343"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.176.6.3635"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/s10020-018-0069-7"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M301484200"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2006.08.013"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2017.07.008"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.153.3.694"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.723967"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.581758"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.189126"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365540310015935"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/shk.0b013e318063e6ca"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.178.2.993"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/4137563"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1385\/CRIAI:19:2:183"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199611000-00001"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01073-15"},{"key":"e_1_3_3_27_2","doi-asserted-by":"crossref","first-page":"720","DOI":"10.4049\/jimmunol.123.2.720","article-title":"Susceptibility of CBA\/N mice to infection with Salmonella typhimurium: influence of the X-linked gene controlling B lymphocyte function","volume":"123","author":"O'Brien AD","year":"1979","unstructured":"O'Brien AD, Scher I, Campbell GH, MacDermott RP, Formal SB. 1979. Susceptibility of CBA\/N mice to infection with Salmonella typhimurium: influence of the X-linked gene controlling B lymphocyte function. J Immunol 123:720\u2013724.","journal-title":"J Immunol"},{"key":"e_1_3_3_28_2","doi-asserted-by":"crossref","first-page":"970","DOI":"10.4049\/jimmunol.159.2.970","article-title":"Endotoxin shock in antibody-deficient mice: unraveling the role of natural antibody and complement in the clearance of lipopolysaccharide","volume":"159","author":"Reid RR","year":"1997","unstructured":"Reid RR, Prodeus AP, Khan W, Hsu T, Rosen FS, Carroll MC. 1997. Endotoxin shock in antibody-deficient mice: unraveling the role of natural antibody and complement in the clearance of lipopolysaccharide. J Immunol 159:970\u2013975.","journal-title":"J Immunol"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.188.12.2381"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2015.11.011"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-01-0207"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40635-016-0096-z"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-001-0261-y"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1996.tb00867.x"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.200324051"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0060476"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1202697"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1086\/427815"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109696200"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.01454"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-11-254185"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-12-259556"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02129"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3884"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00047.2018"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2021.108816"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.shk.0000245016.78493.bb"}],"container-title":["Infection and Immunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/iai.00674-21","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/iai.00674-21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,5]],"date-time":"2023-02-05T16:52:25Z","timestamp":1675615945000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/iai.00674-21"}},"subtitle":[],"editor":[{"given":"Manuela","family":"Raffatellu","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,6,16]]},"references-count":46,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6,16]]}},"alternative-id":["10.1128\/iai.00674-21"],"URL":"https:\/\/doi.org\/10.1128\/iai.00674-21","relation":{},"ISSN":["0019-9567","1098-5522"],"issn-type":[{"value":"0019-9567","type":"print"},{"value":"1098-5522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,16]]},"assertion":[{"value":"2021-12-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00674-21"}}