{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T22:05:26Z","timestamp":1759961126169,"version":"3.41.2"},"reference-count":49,"publisher":"American Society for Microbiology","issue":"12","license":[{"start":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T00:00:00Z","timestamp":1574035200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/501100000265","name":"UK Research and Innovation | Medical Research Council","doi-asserted-by":"publisher","award":["MC_U142684175"],"award-info":[{"award-number":["MC_U142684175"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Infect Immun"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:p>\n            Nontypeable\n            <jats:named-content content-type=\"genus-species\">Haemophilus influenzae<\/jats:named-content>\n            (NTHi) is a major pathogen causing acute otitis media (AOM). The pathology of AOM increases during long-term infection in the middle ear (ME), but the host cellular immune response to bacterial infection in this inflamed environment is poorly understood. Using the\n            <jats:italic>Junbo<\/jats:italic>\n            mouse, a characterized NTHi infection model, we analyzed the cellular response to NTHi infection in the\n            <jats:italic>Junbo<\/jats:italic>\n            mouse middle ear fluid (MEF).\n          <\/jats:p>","DOI":"10.1128\/iai.00689-19","type":"journal-article","created":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T10:43:12Z","timestamp":1568889792000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":8,"title":["Cellular Immune Response against Nontypeable\n            <i>Haemophilus influenzae<\/i>\n            Infecting the Preinflamed Middle Ear of the\n            <i>Junbo<\/i>\n            Mouse"],"prefix":"10.1128","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1096-970X","authenticated-orcid":false,"given":"Pratik P.","family":"Vikhe","sequence":"first","affiliation":[{"name":"Mammalian Genetics Unit, MRC Harwell Institute, Oxfordshire, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"Purnell","sequence":"additional","affiliation":[{"name":"Mammalian Genetics Unit, MRC Harwell Institute, Oxfordshire, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steve D. 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