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We evaluated the early role of these processes in experimentally induced\n            <jats:named-content content-type=\"genus-species\">Plasmodium falciparum<\/jats:named-content>\n            and\n            <jats:named-content content-type=\"genus-species\">P. vivax<\/jats:named-content>\n            infection. Participants were enrolled in induced blood-stage malaria clinical trials. Plasma osteoprotegerin, angiopoietin-2, and von Willebrand Factor (vWF) levels were measured as biomarkers of endothelial activation. 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