{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T05:48:25Z","timestamp":1776923305973,"version":"3.51.2"},"reference-count":29,"publisher":"American Society for Microbiology","issue":"2","license":[{"start":{"date-parts":[[1998,2,1]],"date-time":"1998-02-01T00:00:00Z","timestamp":886291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["Infect Immun"],"published-print":{"date-parts":[[1998,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>\n            We previously reported important differences in resistance to\n            <jats:italic>Taenia crassiceps<\/jats:italic>\n            murine cysticercosis between BALB\/c substrains. It was suggested that resistance might correlate with expression of the nonclassic class I major histocompatibility complex (MHC) Qa-2 antigen; BALB\/cAnN is Qa-2 negative and highly susceptible to\n            <jats:italic>T. crassiceps<\/jats:italic>\n            , whereas BALB\/cJ expresses Qa-2 and is highly resistant. In this study, we investigated the role of Qa-2 in mediating resistance to cysticercosis by linkage analysis and infection of Qa-2 transgenic mice. In BALB\/cAnN \u00d7 (C57BL\/6J \u00d7 BALB\/cAnN)F\n            <jats:sub>1<\/jats:sub>\n            and BALB\/cAnN \u00d7 (BALB\/cJ \u00d7 BALB\/cAnN)F\n            <jats:sub>1<\/jats:sub>\n            backcrosses, the expression of Qa-2 antigen correlated with resistance to cysticercosis. Significantly fewer parasites were recovered from infected Qa-2 transgenic male and female mice than from nontransgenic mice of similar genetic background. These results clearly demonstrate that the Qa-2 MHC antigen is involved in resistance to\n            <jats:italic>T. crassiceps<\/jats:italic>\n            cysticercosis.\n          <\/jats:p>","DOI":"10.1128\/iai.66.2.760-764.1998","type":"journal-article","created":{"date-parts":[[2019,12,31]],"date-time":"2019-12-31T15:23:03Z","timestamp":1577805783000},"page":"760-764","update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":52,"title":["Increased Resistance to\n            <i>Taenia crassiceps<\/i>\n            Murine Cysticercosis in Qa-2 Transgenic Mice"],"prefix":"10.1128","volume":"66","author":[{"given":"Gladis","family":"Fragoso","sequence":"first","affiliation":[{"name":"<!--label omitted: 1-->Department of Immunology, Instituto de Investigaciones Biome\u0301dicas, UNAM, Me\u0301xico D.F. 04510, Me\u0301xico,1 and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edmundo","family":"Lamoyi","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Department of Immunology, Instituto de Investigaciones Biome\u0301dicas, UNAM, Me\u0301xico D.F. 04510, Me\u0301xico,1 and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Mellor","sequence":"additional","affiliation":[{"name":"<!--label omitted: 2-->Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, Georgia 309122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ciro","family":"Lomeli\u0301","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Department of Immunology, Instituto de Investigaciones Biome\u0301dicas, UNAM, Me\u0301xico D.F. 04510, Me\u0301xico,1 and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marisela","family":"Herna\u0301ndez","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Department of Immunology, Instituto de Investigaciones Biome\u0301dicas, UNAM, Me\u0301xico D.F. 04510, Me\u0301xico,1 and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edda","family":"Sciutto","sequence":"additional","affiliation":[{"name":"<!--label omitted: 1-->Department of Immunology, Instituto de Investigaciones Biome\u0301dicas, UNAM, Me\u0301xico D.F. 04510, Me\u0301xico,1 and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"235","reference":[{"key":"e_1_3_2_2_2","unstructured":"Aluja\nA.\nFrequency of porcine cysticercosis in Mexico\nCysticercosis: present state of knowledge and perspectives.\nFlisser\nA.\nWillms\nK.\nLaclette\nJ. 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