{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T14:08:01Z","timestamp":1789740481340,"version":"4.0.1"},"reference-count":156,"publisher":"American Society for Microbiology","license":[{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Bdellovibrio bacteriovorus<\/jats:italic>\n                      is a gram-negative Proteobacterium that has evolved to use a novel, predatory, intrabacterial lifestyle. Once encountered under a microscope, in a lecture, or a textbook, it is seldom forgotten.\n                      <jats:italic toggle=\"yes\">B. bacteriovorus<\/jats:italic>\n                      speedily collides with, enters, modifies, and kills other gram-negative bacteria. Residing inside the periplasm of the dead prey for several hours, it uses prey molecules for growth and replication, only bursting out from that temporary home when its progeny are fully formed predators themselves. Rapid motility whilst hunting contrasts with sessility during prey consumption\u2014these key behaviors, studied by early researchers, have been followed by molecular studies in recent times. Genomic analysis has enabled the linkage and discovery of proteins involved in key regulatory circuits, allied to enzymology describing prey cell manipulation and deconstruction. Indeed, the prey bacterium of a\n                      <jats:italic toggle=\"yes\">B. bacteriovorus<\/jats:italic>\n                      is the natural \u201cpetri dish\u201d of suitable components for predator growth. A fascinating\n                      <jats:italic toggle=\"yes\">B. bacteriovorus<\/jats:italic>\n                      conundrum continues to be: \u201chow does a predator consume materials very similar to those from which it is built, without self-damage?\u201d. More has been discovered and is yet to be learned about these bacterial damaging enzymes: how predators use them in nature and whether they can be applied to assist human conflicts with pathogens. However, the elegance and molecular complexity, with which\n                      <jats:italic toggle=\"yes\">B. bacteriovorus<\/jats:italic>\n                      accomplishes its intrabacterial lifestyle, will continue to challenge researchers and present new biology in the 21st century. New discoveries, tools, and approaches position\n                      <jats:italic toggle=\"yes\">B. bacteriovorus<\/jats:italic>\n                      research for many more breakthroughs.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1128\/jb.00137-26","type":"journal-article","created":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T13:43:02Z","timestamp":1789738982000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":0,"title":["How\n                    <i>Bdellovibrio bacteriovorus<\/i>\n                    became a model for invasive bacterial predation"],"prefix":"10.1128","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1856-7975","authenticated-orcid":true,"given":"Andrew L.","family":"Lovering","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/03angcq70","id-type":"ROR","asserted-by":"publisher"}],"name":"School of Biosciences, University of Birmingham","place":["Birmingham, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6271-2674","authenticated-orcid":true,"given":"R. 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