{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T15:14:34Z","timestamp":1784128474517,"version":"3.55.0"},"reference-count":63,"publisher":"American Society for Microbiology","issue":"11","license":[{"start":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T00:00:00Z","timestamp":1668470400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1128\/ASMCopyrightv2"},{"start":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T00:00:00Z","timestamp":1668470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.asm.org\/non-commercial-tdm-license"}],"funder":[{"DOI":"10.13039\/100000060","name":"HHS | NIH | National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["AI091779"],"award-info":[{"award-number":["AI091779"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"HHS | NIH | National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["GM139186"],"award-info":[{"award-number":["GM139186"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"name":"DOD-SMART Scholarship"}],"content-domain":{"domain":["journals.asm.org"],"crossmark-restriction":true},"short-container-title":["J Bacteriol"],"published-print":{"date-parts":[[2022,11,15]]},"abstract":"<jats:p>\n                    <jats:named-content content-type=\"genus-species\">Streptococcus pyogenes<\/jats:named-content>\n                    causes several important human diseases. This study evaluates how the induction or disruption of a cell-cell communication system alters\n                    <jats:named-content content-type=\"genus-species\">S. pyogenes<\/jats:named-content>\n                    \u2019s gene expression and, in extreme conditions, its physiology.\n                  <\/jats:p>","DOI":"10.1128\/jb.00175-22","type":"journal-article","created":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T09:01:34Z","timestamp":1667206894000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":8,"title":["The Proteomic and Transcriptomic Landscapes Altered by Rgg2\/3 Activity in Streptococcus pyogenes"],"prefix":"10.1128","volume":"204","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3178-4269","authenticated-orcid":true,"given":"Britta E.","family":"Rued","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caleb M.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4554-543X","authenticated-orcid":true,"given":"Michael J.","family":"Federle","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-3835-4"},{"key":"e_1_3_3_3_2","unstructured":"Sims Sanyahumbi A Colquhoun S Wyber R Carapetis JF. 2016. Global disease burden of group A Streptococcus . In Ferretti JJ Stevens DL Fischetti VA (ed.) Streptococcus pyogenes : basic biology to clinical manifestations [Internet]. University of Oklahoma Health Sciences Center Oklahoma City OK."},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1873-3468.12254"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2017.01.007"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00701-17"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00169-18"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2018.02.002"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-10556-8"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.03400-20"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-genet-120116-023507"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00877-06"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2014.00127"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.13088"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1705972114"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002190"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00333-12"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.13216"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0168461"},{"key":"e_1_3_3_20_2","first-page":"202008427","article-title":"Structure\u2013function studies of Rgg binding to pheromones and target promoters reveal a model of transcription factor interplay","volume":"9","author":"Capodagli GC","year":"2020","unstructured":"Capodagli GC, Tylor KM, Kaelber JT, Petrou VI, Federle MJ. 2020. Structure\u2013function studies of Rgg binding to pheromones and target promoters reveal a model of transcription factor interplay. Proc Natl Acad Sci USA 9:202008427.","journal-title":"Proc Natl Acad Sci USA"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00464-20"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.00176-22"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.7b00701"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-0716-0467-0_9"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrg3185"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-020-0258-4"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.183.18.5376-5384.2001"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01162"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2000.02203.x"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.183.24.7354-7364.2001"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-genet-021821-025827"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.02083"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1111\/mmi.14866"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2013.11.013"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2005.01.001"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01188-18"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00917-07"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00288-08"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1803220115"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00382-13"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1722514115"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1128\/genomeA.00612-13"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.2009.06669.x"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1002\/9780471729259.mc09d03s30"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3252"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2004-5-10-r80"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz114"},{"key":"e_1_3_3_48_2","unstructured":"Morgan M Pages H Obenchain V Hayden N. 2021. Rsamtools: binary alignment (BAM) FASTA variant call (BCF) and tabix file import. 2.8.0. R package."},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp616"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gks042"},{"key":"e_1_3_3_51_2","unstructured":"Storey J Bass A Dabney A Robinson D. 2021. qvalue: Q-value estimation for false discovery rate control. 2.24.0. R package."},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-9-488"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(05)80360-2"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btq249"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.2.822-831.2001"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1006\/meth.2001.1262"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2377"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac025747h"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1511"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv007"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517-6161.1995.tb02031.x"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaa1100"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky1106"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2089"}],"container-title":["Journal of Bacteriology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jb.00175-22","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.asm.org\/doi\/pdf\/10.1128\/jb.00175-22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T09:00:59Z","timestamp":1668502859000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.asm.org\/doi\/10.1128\/jb.00175-22"}},"subtitle":[],"editor":[{"given":"Tina M.","family":"Henkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,11,15]]},"references-count":63,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11,15]]}},"alternative-id":["10.1128\/jb.00175-22"],"URL":"https:\/\/doi.org\/10.1128\/jb.00175-22","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2022.05.06.490990","asserted-by":"object"}]},"ISSN":["0021-9193","1098-5530"],"issn-type":[{"value":"0021-9193","type":"print"},{"value":"1098-5530","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,15]]},"assertion":[{"value":"2022-05-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00175-22"}}