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As a vector-borne pathogen,\n            <jats:named-content content-type=\"genus-species\">Y. pestis<\/jats:named-content>\n            fluctuates between an arthropod vector (flea) and mammalian host. As such,\n            <jats:named-content content-type=\"genus-species\">Y. pestis<\/jats:named-content>\n            must recognize environmental signals encountered within each host environment and respond by appropriately regulating gene expression. PsaA is a key\n            <jats:named-content content-type=\"genus-species\">Y. pestis<\/jats:named-content>\n            mammalian virulence determinant that forms fimbriae. Our work provides evidence that\n            <jats:named-content content-type=\"genus-species\">Y. pestis<\/jats:named-content>\n            utilizes multiple posttranscriptional mechanisms to regulate the levels of two PsaA regulatory proteins in response to both temperature and pH. This study offers insight into mechanisms that bacteria utilize to sense environmental cues and regulate the expression of determinants required for mammalian disease.\n          <\/jats:p>","DOI":"10.1128\/jb.00217-19","type":"journal-article","created":{"date-parts":[[2019,5,25]],"date-time":"2019-05-25T10:36:51Z","timestamp":1558780611000},"update-policy":"https:\/\/doi.org\/10.1128\/asmj-crossmark-policy-page","source":"Crossref","is-referenced-by-count":14,"title":["Temperature Control of\n            <i>psaA<\/i>\n            Expression by PsaE and PsaF in Yersinia pestis"],"prefix":"10.1128","volume":"201","author":[{"given":"Joshua D.","family":"Quinn","sequence":"first","affiliation":[{"name":"Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric H.","family":"Weening","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taryn A.","family":"Miner","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia L.","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA"},{"name":"Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"235","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.10.1.35"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1078\/1438-4639-00259"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ento.50.071803.130337"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0509544103"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-12-147"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004587"},{"key":"e_1_3_3_8_2","first-page":"85","article-title":"A review of plague persistence with special emphasis on fleas","volume":"46","author":"Wimsatt J","year":"2009","unstructured":"Wimsatt J, Biggins DE. 2009. 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