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While model systems such as\n                    <jats:named-content content-type=\"genus-species\">Escherichia coli<\/jats:named-content>\n                    have shown that PBP1A is associated with side wall peptidoglycan synthesis, we show herein that\n                    <jats:named-content content-type=\"genus-species\">A. baumannii<\/jats:named-content>\n                    PBP1A directly interacts with the divisome component PBP3 to promote division, suggesting a unique role for the enzyme in this highly drug-resistant nosocomial pathogen.\n                    <jats:named-content content-type=\"genus-species\">A. baumannii<\/jats:named-content>\n                    demonstrated unanticipated resistance and tolerance to envelope-targeting antibiotics, which may be driven by rewired peptidoglycan machinery and may underlie therapeutic failure during antibiotic treatment.\n                  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